3 completed, 2 recruiting, 1 active not recruiting, 1 no longer available. 4 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Recruiting 2 |
| Phase 3 | 2 | Active not recruiting 1, Completed 1 |
Follow apitegromab: new trials by email Literature Review of apitegromab trials Research Report on apitegromab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD Apitegromab, Placebo - Facioscapulohumeral Muscular Dystrophy, FSHD | Phase 2 | Recruiting | Scholar Rock, Inc. | 60 | 2026-07-30 | 2026-09-02 |
| A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy Apitegromab, Nusinersen, Risdiplam - Spinal Muscular Atrophy, SMA | Phase 2 | Recruiting | Scholar Rock, Inc. | 52 | 2025-09-15 | 2026-10-02 |
| Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese Apitegromab, Placebo, Tirzepatide - Overweight and Obesity | Phase 2 | Completed | Scholar Rock, Inc. | 102 | 2024-05-21 | 2026-01-23 |
| Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab Apitegromab - Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3 | Phase 3 | Active not recruiting | Scholar Rock, Inc. | 238 | 2023-04-17 | 2026-09-01 |
| Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam Apitegromab, Placebo - Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3 | Phase 3 | Completed | Scholar Rock, Inc. | 188 | 2022-04-14 | 2026-01-22 |
| An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy SRK-015 - Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3 | Phase 2 | Completed | Scholar Rock, Inc. | 58 | 2019-04-22 | 2024-12-02 |
| EAP of Apitegromab for Patients With Spinal Muscular Atrophy Apitegromab - SMA | No longer available | Scholar Rock, Inc. | 2026-04-28 |
Muscular Atrophy, Spinal (4) · Neuromuscular Manifestations (4) · Spinal Muscular Atrophies of Childhood (4) · Atrophy (3) · Muscular Atrophy (3) · Neuromuscular Diseases (3) · Muscular Dystrophy, Facioscapulohumeral (1) · Obesity (1) · Overweight (1)
United States (6) · Italy (4) · Netherlands (4) · Spain (4) · Belgium (3) · France (3) · United Kingdom (3) · Germany (2) · Poland (2)