3 completed, 1 active not recruiting, 1 recruiting, 1 unknown. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 3, Active not recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Eye Manifestations: new trials by email Literature Review of Eye Manifestations trials Research Report on Eye Manifestations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess Safety, Tolerability, and Pharmacokinetics of Ascending Concentrations of Topical Ocular BL1332 in Healthy Volunteers BL1332 ophthalmic solution, BL1332 ophthalmic vehicle - Ocular Pain | Phase 1 | Active not recruiting | Bausch & Lomb Incorporated | 24 | 2025-07-29 | 2026-01-27 |
| Efficacy and Safety of Topical Cyclosporine 0.05% and Lifitgrast on the Ocular Surface Symptom After Photorefractive Keratectomy in Feiz Hospital, Isfahan, 2024 Group 1 drug, Group 2: Drug and placebo, Group 3: Drug and palcebo - Ocular Surface Symptom, Ocular Surface Disease | Phase 1 | Unknown | Mohsen Pourazizi | 150 | 2024-10-30 | 2024-10-03 |
| Safety and Tolerability of EO2002 EO2002, Sham injection - Cataract, Endothelial Cell Loss, Corneal | Phase 1 | Recruiting | Asociación para Evitar la Ceguera en México | 32 | 2022-08-30 | 2025-12-08 |
| Evaluation of the Safety, Systemic Pharmacokinetics, and Tolerability Loteprednol Etabonate Ophthalmic Gel - Eye Pain | Phase 1 | Completed | Bausch Health Americas, Inc. | 15 | 2015-02-01 | 2017-02-24 |
| Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain SYL1001, Placebo - Ocular Pain, Dry Eye Syndrome | Phase 1 / Phase 2 | Completed | Sylentis, S.A. | 60 | 2012-11-01 | 2015-05-25 |
| Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers SYL1001 - Ocular Pain, Dry Eye | Phase 1 | Completed | Sylentis, S.A. | 30 | 2011-07-01 | 2012-07-17 |
Eye Pain (5) · Dry Eye Syndromes (2) · Cataract (1) · Corneal Endothelial Cell Loss (1) · Endophthalmitis (1)
Eye Diseases (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Neurologic Manifestations (5) · Pain (5) · Lacrimal Apparatus Diseases (2) · Corneal Diseases (1) · Eye Infections (1) · Infections (1) · Lens Diseases (1) · Pathologic Processes (1) · Postoperative Complications (1)
Pharmaceutical Preparations (1) · salicylhydroxamic acid (1)
Sylentis, S.A. (2) · Asociación para Evitar la Ceguera en México (1) · Bausch & Lomb Incorporated (1) · Bausch Health Americas, Inc. (1) · Mohsen Pourazizi (1)
Spain (2) · United States (2) · Iran (1) · Mexico (1)
Belen Sadaba, MD, PhD (1) · Denise Ramjit (1) · Valeria Sanchez Huerta, MD (1)