61 completed, 19 unknown, 8 terminated, 5 recruiting. 33 Not applicable, 12 Phase 4, 8 Phase 2, 8 Phase 3, 3 Phase 1.
Follow ESRD: new trials by email Literature Review of ESRD trials Research Report on ESRD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ultrasound Guidance Intercostobrachial Nerve Block in AVF Superficialization Distal Intercostobrachial Nerve Block, Supraclavicular Plexus Block Procedure (SCPB) - Supraclavicular Plexus Block Procedure (SCPB), ESRD | Not applicable | Not yet recruiting | Assiut University | 76 | 2026-10-01 | 2026-10-07 |
| Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis Canagliflozin 300 MG - ESRD, CKD (Chronic Kidney Disease) Stage 5D | Phase 2 | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 30 | 2026-02-01 | 2026-03-16 |
| Adding Urea to the Final Dialysis Fluid Urea in the dialysate - Dysequilibrium Syndrome, ESRD | Phase 1 / Phase 2 | Recruiting | University of California, San Francisco | 20 | 2025-09-16 | 2026-02-12 |
| Repletion of Ergothioneine in Patients With Kidney Failure Ergothioneine, Placebo - Esrd | Not applicable | Recruiting | Stanford University | 28 | 2025-04-01 | 2026-04-01 |
| Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis Fexofenadine, Gabapentin - Uremic Pruritus, Chronic Kidney Disease-associated Pruritus | Phase 4 | Completed | Tanta University | 60 | 2024-07-01 | 2025-04-27 |
| Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision Kidney Offer Shared Decision Making - End Stage Renal Disease, End-Stage Kidney Disease | Not applicable | Completed | Hennepin Healthcare Research Institute | 100 | 2024-04-03 | 2026-04-13 |
| Safety and Efficacy Assessments of NeoKidney® in ESRD Patients Treated With Short Daily Hemodialysis NeoKidney - End Stage Renal Disease, ESRD | Not applicable | Completed | Nextkidney S.A. | 5 | 2024-03-11 | 2026-10-30 |
| Early Feasibility Study to Evaluate the Safety and Efficacy of PAK HD in ESRD Patients PAK HD Sorbent Therapy - End Stage Renal Disease, ESRD | Not applicable | Completed | Nextkidney S.A. | 3 | 2024-02-22 | 2025-04-01 |
| SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study SelfWrap Bioabsorbable Perivascular Wrap, Untreated AVF Control - Chronic Kidney Diseases, End Stage Renal Disease | Not applicable | Recruiting | VenoStent | 600 | 2024-01-03 | 2026-02-17 |
| A Post-Market Clinical Performance and Safety Evaluation of GamCath HighFlow Dolphin Protect Catheter Vascular access catheter to support dialysis or CRRT - AKI - Acute Kidney Injury, Acute Renal Failure | Completed | Vantive Health LLC | 76 | 2023-12-07 | 2025-03-13 | |
| SAfety of Regional Citrate Anticoagulation (SARCA Study) Dialysis - Acute Kidney Injury, ESRD | Phase 3 | Completed | Fresenius Medical Care North America | 32 | 2023-10-17 | 2026-09-11 |
| Impact Of Mindfulness Meditation On Pain, Quality Of Sleep, Self-Esteem Mindfulness meditation - ESRD | Not applicable | Completed | Jordan University of Science and Technology | 60 | 2023-04-01 | 2023-10-03 |
| The Evaluation of the DIMI RRT System In-Center to Demonstrate Safety and Usability in the Home Environment The DIMI Renal Replacement Therapy (RRT) System - ESRD, Hemodialysis | Not applicable | Withdrawn | Dialco Medical Inc. | 2023-01-01 | 2024-03-22 | |
| TESTING -ON Post-Trial ObservatioNal Cohort Study IgA Nephropathy, ESRD | Completed | The George Institute | 211 | 2022-12-07 | 2026-07-09 | |
| Safety and Efficacy of Canagliflozin in Advanced CKD Invokana 300 mg and 100 mg tablet - ESRD, CKD Stage 4 | Phase 4 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 34 | 2022-11-24 | 2026-07-13 |
| A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery Sirolimus - Complication of Renal Dialysis, End Stage Renal Disease | Phase 3 | Completed | Vascular Therapies, Inc. | 136 | 2022-08-26 | 2026-10-06 |
| Long Term Hemodialysis Catheters (LTHD) Post Market Clinical Follow up (PMCF) Long term hemodialysis catheter - CKD, ESRD | Withdrawn | Medical Components, Inc dba MedComp | 2022-03-30 | 2024-01-10 | ||
| A Single-center Pilot Study Evaluating a Preemptive Short Course of Glecaprevir/Pibrentasvir in Hepatitis C Positive to Negative Kidney Transplantation Glecaprevir/pibrentasvir - ESRD | Early Phase 1 | Completed | NYU Langone Health | 20 | 2022-03-20 | 2024-06-25 |
| Evaluate Serious Illness Treatment Preferences and Outcomes in the Patients Receiving Peritoneal Dialysis integrated palliative care - ESRD, Peritoneal Dialysis | Not applicable | Unknown | National Taiwan University Hospital | 500 | 2022-02-01 | 2022-01-28 |
| StatStrip A Glucose/Creatinine Meter System Lay User Study Evaluation Glucose, Creatinine - Diabete Mellitus, CKD | Completed | Nova Biomedical | 175 | 2021-10-28 | 2022-09-28 |
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Kidney Failure, Chronic (97) · Renal Insufficiency (9) · Renal Insufficiency, Chronic (8) · Kidney Diseases (7) · Hyperphosphatemia (6) · Arteriovenous Fistula (5) · Diabetes Mellitus (4) · Cardiovascular Diseases (3) · Acute Kidney Injury (2) · Fabry Disease (2) · Hyperkalemia (2) · Hypertension (2) · Malnutrition (2) · Phosphorus Metabolism Disorders (2) · Pulmonary Disease, Chronic Obstructive (2)
Chronic Disease (97) · Disease Attributes (97) · Female Urogenital Diseases (97) · Female Urogenital Diseases and Pregnancy Complications (97) · Male Urogenital Diseases (97) · Pathologic Processes (97) · Pathological Conditions, Signs and Symptoms (97) · Urogenital Diseases (97) · Urologic Diseases (96) · Kidney Diseases (90) · Renal Insufficiency, Chronic (89) · Renal Insufficiency (88) · Nutritional and Metabolic Diseases (19) · Metabolic Diseases (16) · Cardiovascular Diseases (10)
ferric citrate (4) · Surveys and Questionnaires (3) · Acetylcysteine (2) · Canagliflozin (2) · Icodextrin (2) · Kidney Transplantation (2) · Nutrineal (2) · Pioglitazone (2) · Renal Dialysis (2) · Sevelamer (2) · Sirolimus (2) · Antigens, Surface (1) · Baths (1) · Blood Vessel Prosthesis (1) · Citric Acid (1)
Satellite Healthcare (6) · Assiut University (4) · Fresenius Medical Care North America (3) · Vantive Health LLC (3) · Assaf-Harofeh Medical Center (2) · Central Hospital, Nancy, France (2) · Johns Hopkins University (2) · Laminate Medical Technologies (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · National Taiwan University Hospital (2) · Nextkidney S.A. (2) · Panion & BF Biotech Inc. (2) · Renal Research Institute (2) · Stanford University (2) · University of California, San Francisco (2)
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Wael F Hussein, MBBS (5) · Leonid S Feldman, MD (2) · Noam Zilberman (2) · Sriram Iyer, MD (2) · Aarti Mathur, MD, PhD (1) · Ahmed F Elkeraie, MD (1) · Ahmed M Hussein, PhD (1) · Alex Gold, MD (1) · Alp Ikizler, M.D. (1) · Anne Zanchi, MD (1) · Antanole Bearabe, MD (1) · Bo Feldt-Rasmussen, MD DMSc (1) · Bo Shen, MD (1) · Bonnie Lonze, MD, PhD (1)
PMID 40576086, PMID 12138146, PMID 15492943, PMID 19738091, PMID 20805263, PMID 21613795, PMID 21940484, PMID 21996389, PMID 22067309, PMID 24840781, PMID 25330088, PMID 26510186, PMID 27348271, PMID 27769897, PMID 28213388, PMID 28348181, PMID 29027352, PMID 29994980, PMID 30102825, PMID 31034642, PMID 31080776, PMID 31707860, PMID 32282660, PMID 32750456, PMID 32800660, PMID 32883245, PMID 33037746, PMID 33355235, PMID 33559851, PMID 33835939, PMID 34432869, PMID 34559944, PMID 35018639, PMID 35524363, PMID 35659156, PMID 37651553, PMID 37928754, PMID 38046912, PMID 38178557, PMID 38227032, PMID 38384289, PMID 39430196, PMID 39761595, PMID 40952584
2015 (1), 2025 (1), P01HL075462 (1), P30AG048773 (1), R01DK114074 (1), R01DK134482 (1), R44HL064462 (1), UH2AG050311 (1)