27 completed, 8 recruiting, 7 unknown, 5 active not recruiting. 28 Not applicable, 7 Phase 3, 3 Phase 1, 2 Phase 2, 2 Phase 4.
Follow End Stage Kidney Disease: new trials by email Literature Review of End Stage Kidney Disease trials Research Report on End Stage Kidney Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease Standard Table Salt, Salt Substitute - End Stage Kidney Disease | Not applicable | Not yet recruiting | NYU Langone Health | 20 | 2027-01-15 | 2026-03-12 |
| Virtual Reality in End Stage Kidney Disease Social Virtual Reality, Individual Virtual Reality - End Stage Kidney Disease | Not applicable | Completed | University of Pennsylvania | 54 | 2026-03-30 | 2026-10-07 |
| A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function LY3841136 - Kidney Disease, Renal Insufficiency Chronic | Phase 1 | Active not recruiting | Eli Lilly and Company | 28 | 2026-02-24 | 2026-08-19 |
| Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants Moda-flx Hemodialysis System™ - End Stage Kidney Disease | Not applicable | Recruiting | Diality Inc. | 50 | 2025-10-06 | 2026-07-06 |
| The Reducing Adverse Outcomes in Dialysis by Adjusting the pRescription for Dialysate Potassium Trial PKRxHD, Dialysis - End Stage Kidney Disease | Not applicable | Not yet recruiting | NYU Langone Health | 120 | 2025-08-01 | 2025-07-04 |
| An Observational Study of Patients With Chronic Kidney Disease Observational - Kidney Disease, Chronic, End Stage Kidney Disease | Withdrawn | Target PharmaSolutions, Inc. | 2025-04-01 | 2025-12-17 | ||
| First Evaluation of the Moda-Flx Hemodialysis System™ in Real World Clinical Settings Moda-flx Hemodialysis System - End Stage Renal Disease, End Stage Renal Disease on Dialysis | Not applicable | Completed | Diality Inc. | 12 | 2024-12-09 | 2025-06-22 |
| meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis Empagliflozin 25 MG - Peritoneal Dialysis Complication, End Stage Kidney Disease | Phase 3 | Recruiting | University Health Network, Toronto | 20 | 2024-09-01 | 2026-05-01 |
| Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD) CSL300, Placebo - End Stage Kidney Disease | Phase 2 / Phase 3 | Recruiting | CSL Behring | 3110 | 2024-04-27 | 2026-09-21 |
| Alio WEAR Study: Long-term Wear of the Alio Platform Alio platform - End Stage Kidney Disease | Not applicable | Unknown | Alio, Inc. | 250 | 2023-10-09 | 2023-10-11 |
| Immunological Tolerance in Patients With Mismatched Kidney Transplants Donor CD34+, CD3+. and belumosudil - End Stage Kidney Disease, Immunological Tolerance | Phase 1 | Active not recruiting | University of California, Los Angeles | 16 | 2023-07-07 | 2025-11-26 |
| Symptom Monitoring in Hemodialysis Symptom Monitoring on Renal Replacement Therapy - Hemodialysis (SMaRRT-HD), Usual Care - End Stage Kidney Disease | Not applicable | Recruiting | University of Pennsylvania | 2400 | 2023-06-24 | 2025-11-24 |
| Virtual Reality in Hemodialysis to Improve Psychological Well-being Joviality(TM), Inert Virtual Reality - End Stage Kidney Disease, Depressive Symptoms | Not applicable | Active not recruiting | University of Illinois at Urbana-Champaign | 61 | 2023-06-22 | 2026-02-18 |
| Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2 PLS240, Placebo, Open-Label Extension PLS240 - Secondary Hyperparathyroidism, End Stage Kidney Disease | Phase 3 | Completed | Pathalys Pharma | 412 | 2023-05-15 | 2025-09-09 |
| Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants Conditioning and Stem cell infusion - End Stage Kidney Disease, Immunological Tolerance | Phase 1 | Recruiting | University of California, Los Angeles | 10 | 2022-12-21 | 2025-11-26 |
| Hemodynamics in Chronic Hemodialysis Patients Undergoing Isolated Ultrafiltration Compared to Conventional Hemodialysis isolated Ultrafiltration (iso-UF) - End Stage Kidney Disease | Not applicable | Recruiting | Medical University of Graz | 32 | 2022-11-02 | 2026-10-08 |
| Pain Reduction Using NEurostimulation Study Active tDCS, Sham tDCS - End Stage Kidney Disease, Chronic Pain | Not applicable | Active not recruiting | Weill Medical College of Cornell University | 125 | 2022-10-24 | 2026-05-15 |
| A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery Sirolimus - Complication of Renal Dialysis, End Stage Renal Disease | Phase 3 | Completed | Vascular Therapies, Inc. | 136 | 2022-08-26 | 2026-10-06 |
| Continuous Glucose Monitoring in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes Continuous glucose monitoring (CGM) - End Stage Kidney Disease | Not applicable | Completed | Emory University | 40 | 2022-08-10 | 2024-04-05 |
| Effect of Low Versus Standard Dialysate Sodium on 48h Ambulatory BP in Patients With Intradialytic Hypertension dialysis with low dialysate sodium concentration, dialysis with standard dialysate sodium concentration - Intradialytic Hypertension, End Stage Kidney Disease | Not applicable | Completed | Aristotle University Of Thessaloniki | 30 | 2022-06-01 | 2024-10-16 |
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Kidney Failure, Chronic (53) · Renal Insufficiency, Chronic (12) · Arteriovenous Fistula (6) · Renal Insufficiency (6) · Kidney Diseases (3) · Motor Activity (3) · Acute Kidney Injury (2) · COVID-19 (2) · Cardiovascular Diseases (2) · Depression (2) · Fistula (2) · Hyperparathyroidism, Secondary (2) · Myocardial Infarction (2) · Rejection, Psychology (2) · Acute Coronary Syndrome (1)
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Diality Inc. (2) · NYU Langone Health (2) · Satellite Healthcare (2) · University of California, Los Angeles (2) · University of Leicester (2) · University of Pennsylvania (2) · Vascular Therapies, Inc. (2) · A.C. Abrahams (1) · Alio, Inc. (1) · Aristotle University Of Thessaloniki (1) · C. R. Bard (1) · CSL Behring (1) · Columbia University (1) · Duke University (1) · Eli Lilly and Company (1)
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PMID 21388319, PMID 26444846, PMID 28151412, PMID 28767349, PMID 29424935, PMID 30723975, PMID 31299919, PMID 31672793, PMID 32450917, PMID 32528722, PMID 34548369, PMID 35042554, PMID 35190440, PMID 35383044, PMID 36801430, PMID 37092011, PMID 37322595, PMID 37327026, PMID 37343576, PMID 38085705, PMID 38710537, PMID 38796655, PMID 38881397, PMID 39498822, PMID 40101671, PMID 40889553
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