2 completed, 2 recruiting, 1 active not recruiting, 1 terminated. 5 Phase 1, 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 2, Active not recruiting 1, Recruiting 1, Terminated 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow CD3 Complex: new trials by email Literature Review of CD3 Complex trials Research Report on CD3 Complex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors ONC-783 - Advanced Solid Tumor | Phase 1 | Recruiting | OncoC4, Inc. | 20 | 2026-08-10 | 2026-09-08 |
| Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma Obinutuzumab, Glofitamab, Pirtobrutinib - Mantle Cell Lymphoma | Phase 2 | Recruiting | University of California, San Francisco | 30 | 2024-06-11 | 2026-10-01 |
| Immunological Tolerance in Patients With Mismatched Kidney Transplants Donor CD34+, CD3+. and belumosudil - End Stage Kidney Disease, Immunological Tolerance | Phase 1 | Active not recruiting | University of California, Los Angeles | 16 | 2023-07-07 | 2025-11-26 |
| The Expression of Immune Checkpoint CD28 rs1980422-related Single-nucleotide Polymorphisms in the Primary Immune Thrombocytopenia Genotyping of rs1980422-related single-nucleotide polymorphisms by real time PCR - Immune Thrombocytopenia | Not applicable | Unknown | Sohag University | 100 | 2022-09-01 | 2022-07-21 |
| MCLA-117 in Acute Myelogenous Leukemia MCLA-117 bispecific antibody - Acute Myelogenous Leukemia, Acute Myeloid Leukemia | Phase 1 | Terminated | Merus B.V. | 80 | 2016-04-01 | 2025-04-06 |
| ABR-217620 in Combination With Docetaxel in Patients With Advanced Non-small Cell Lung Cancer ABR-217620, docetaxel - Carcinoma, Non-Small-Cell Lung | Phase 1 | Completed | Active Biotech AB | 13 | 2005-11-01 | 2014-08-27 |
| ABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic Cancer ABR-217620 - Non-Small-Cell Lung Carcinoma, Renal Cell Carcinoma | Phase 1 | Completed | Active Biotech AB | 44 | 2003-04-01 | 2014-08-27 |
Carcinoma, Non-Small-Cell Lung (2) · Carcinoma, Renal Cell (1) · Kidney Failure, Chronic (1) · Leukemia, Myeloid, Acute (1) · Lymphoma, Mantle-Cell (1) · Neoplasm, Residual (1) · Pancreatic Neoplasms (1) · Purpura, Thrombocytopenic, Idiopathic (1) · Recurrence (1) · Rejection, Psychology (1) · Renal Insufficiency, Chronic (1)
Active Biotech AB (2) · Merus B.V. (1) · OncoC4, Inc. (1) · Sohag University (1) · University of California, Los Angeles (1) · University of California, San Francisco (1)
United States (6) · Belgium (1) · Denmark (1) · Egypt (1) · France (1) · Italy (1) · Netherlands (1) · Norway (1) · Russia (1) · United Kingdom (1)
Suzanne Kilany (2) · Jorge Cortes, MD, PhD (1) · Madhav Seshadri, MD (1) · Ruth He, MD, PhD (1)
2015 (1)