10 terminated. 10 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Terminated 10 |
| Phase 2 | 3 | Terminated 3 |
Follow Dwarfism: new trials by email Literature Review of Dwarfism trials Research Report on Dwarfism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Long-Term Safety Study of Somavaratan in Japanese Children With Growth Hormone Deficiency Somavaratan - Growth Hormone Deficiency | Phase 3 | Terminated | Versartis Inc. | 21 | 2017-03-31 | 2018-03-09 |
| Study of TV-1106 in Growth Hormone-Deficient Adults TV-1106, Placebo - Growth Hormone Deficiency | Phase 3 | Terminated | Teva Branded Pharmaceutical Products R&D, Inc. | 14 | 2015-04-30 | 2022-01-24 |
| Study to Assess Safety and Tolerability in Adults With Growth Hormone-Deficiency (GHD) TV-1106, dGH - Growth Hormone Deficiency | Phase 3 | Terminated | Teva Branded Pharmaceutical Products R&D, Inc. | 34 | 2015-04-30 | 2021-12-10 |
| Versartis Long-Term Safety Study of Somavaratan somavaratan - Pediatric Growth Hormone Deficiency | Phase 2 / Phase 3 | Terminated | Versartis Inc. | 385 | 2014-03-03 | 2018-03-09 |
| A Phase 3, Multicenter Study To Evaluate The Efficacy And Safety Of MOD-4023 In Adults With Growth Hormone Deficiency MOD-4023, Placebo - Adult Growth Hormone Deficiency | Phase 3 | Terminated | OPKO Health, Inc. | 202 | 2013-06-01 | 2022-08-12 |
| Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study Saizen® - Growth Hormone Deficiency (GHD) | Phase 3 | Terminated | EMD Serono | 59 | 2010-10-01 | 2013-08-07 |
| Clinical Trial of Growth Hormone in MPS I, II, and VI Somatropin (DNA origin) - Mucopolysaccharidosis I, Mucopolysaccharidosis II | Phase 2 / Phase 3 | Terminated | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 2 | 2008-11-01 | 2018-09-05 |
| Efficacy of Somatropin in Adult Patients With Isolated Growth Hormone Deficiency Placebo, Somatropin - Growth Hormone Deficiency | Phase 3 | Terminated | Pfizer | 9 | 2008-05-01 | 2013-03-04 |
| Growth Hormone in Children With Juvenile Rheumatoid Arthritis (JRA) and With Crohn's Disease somatropin [rDNA origin] for injection - Arthritis, Juvenile Rheumatoid, Crohn Disease | Phase 2 / Phase 3 | Terminated | Nationwide Children's Hospital | 10 | 2007-08-01 | 2018-04-12 |
| Treatment of Children and Adolescents With Growth Failure Associated With Primary IGF-1 Deficiency rh IGF-1 (mecasermin) - Growth Disorders | Phase 3 | Terminated | Ipsen | 114 | 2005-11-01 | 2020-08-14 |
Dwarfism, Pituitary (7) · Growth Disorders (2) · Arthritis, Juvenile (1) · Chronic Disease (1) · Crohn Disease (1) · Failure to Thrive (1) · Mucopolysaccharidosis I (1) · Mucopolysaccharidosis II (1) · Mucopolysaccharidosis VI (1) · Sudden Infant Death (1)
Bone Diseases (10) · Bone Diseases, Developmental (10) · Endocrine System Diseases (10) · Musculoskeletal Diseases (10) · Nervous System Diseases (8) · Bone Diseases, Endocrine (7) · Brain Diseases (7) · Central Nervous System Diseases (7) · Hypopituitarism (7) · Hypothalamic Diseases (7) · Pituitary Diseases (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Pathologic Processes (4)
Human Growth Hormone (5) · albusomatropin (2) · Growth Hormone (1) · MOD-4023 (1) · WW Domain-Containing Oxidoreductase (1) · mecasermin (1)
Teva Branded Pharmaceutical Products R&D, Inc. (2) · Versartis Inc. (2) · EMD Serono (1) · Ipsen (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Nationwide Children's Hospital (1) · OPKO Health, Inc. (1) · Pfizer (1)
United States (6) · Austria (2) · Czechia (2) · Greece (2) · Hungary (2) · Italy (2) · France (1) · Germany (1) · Israel (1) · Russia (1) · Slovakia (1) · Spain (1)
Will Charlton, MD (2) · Dana S Hardin, MD (1) · Lynda E Polgreen, M.D. (1) · Sr Vice President, Clinical Development and Medical Affairs (1)
2014 (1), 2019 (1)