14 completed, 5 unknown, 2 recruiting, 2 terminated. 7 Not applicable, 3 Phase 4, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Unknown 2 |
| Phase 4 | 3 | Completed 1, Enrolling by invitation 1, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Drug Resistance: new trials by email Literature Review of Drug Resistance trials Research Report on Drug Resistance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor Rifaximin - ACS - Acute Coronary Syndrome, Ticagrelor | Phase 4 | Not yet recruiting | Collegium Medicum w Bydgoszczy | 50 | 2026-01-01 | 2025-10-02 |
| Epidemiology of Antimicrobial-use and Antimicrobial-resistant Infections in Four Hospitals in Thailand Drug Resistance, Bacterial | Active not recruiting | University of Oxford | 108000 | 2025-12-01 | 2026-08-14 | |
| Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Malignant Solid Tumors Low-dose radiotherapy to the intestine (ILDR), PD-1/PD-L1 monoclonal antibodies - Radiotherapy, Metastatic Solid Cancers | Phase 2 | Recruiting | Chuangzhen Chen | 48 | 2025-09-26 | 2025-11-20 |
| Artemisinin Partial Resistance in Ethiopian Plasmodium Falciparum: A Multisite Clinical, Molecular and In Vitro Study Artemether-Lumefantrine Tab 20-120mg - Malaria (Plasmodium Falciparum), Drug Resistance | Not applicable | Completed | Didier Menard | 277 | 2024-05-01 | 2026-04-14 |
| B-free Multistage Trial DOR/DTG/3TC - HIV, Drug Resistance | Phase 4 | Enrolling by invitation | Insel Gruppe AG, University Hospital Bern | 210 | 2023-11-13 | 2024-12-04 |
| Real-World Study of Post-Resistance Treatment Strategies in Advanced Breast Cancer Following CDK4/6i, PIK3CA Inhibitors, or T-DXd Metastatic Breast Cancer, Drug Resistance | Recruiting | Hunan Cancer Hospital | 200 | 2023-01-01 | 2025-07-18 | |
| HRD and Resistance to PAPPi in EOC Patients Testing of homologous recombination deficiency - Epithelial Ovarian Cancer, Homologous Recombination Deficiency | Unknown | Lei Li | 400 | 2022-03-26 | 2022-04-04 | |
| Mechanisms fo Clopidogrel Resistance in Older Adults (CEPAGE) additional blood sample - Drug Resistance | Completed | Rennes University Hospital | 37 | 2021-07-12 | 2026-03-31 | |
| Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae Combined antibiotic regimens, Standard antibiotic regimens - Drug Resistance, Carbapenem-Resistant Enterobacteriaceae Infection | Not applicable | Unknown | Phramongkutklao College of Medicine and Hospital | 102 | 2020-09-01 | 2020-08-26 |
| Human Soil Transmitted Helminths (STH) Resistance to Benzimidazole in School Aged Children Living in Gabon Benzimidazole Anthelmintic - Helminths Infection, Drug Resistance | Phase 4 | Completed | Centre de Recherche Médicale de Lambaréné | 255 | 2019-11-11 | 2021-08-02 |
| The Relationship Between Renal Functions and Multi Drug Resistant Organisms Chronic Kidney Disease, Glomerular Filtration Rate | Completed | Konya Numune Hospital | 133 | 2019-08-01 | 2024-03-12 | |
| The Emergence of RAS Mutations in Metastatic Colorectal Cancer Patients Receiving Cetuximab Treatment Cetuximab, liquid biopsy - Colorectal Cancer, Drug Resistance | Unknown | National Health Research Institutes, Taiwan | 120 | 2018-01-01 | 2018-01-17 | |
| Comparison of Bismuth Containing Quadruple Therapy and Based Tailored Therapy for H. Pylori Infection Helicobacter pylori PCR test, CLO test - Helicobacter Pylori Infection, Compliance, Patient | Not applicable | Unknown | Inha University Hospital | 300 | 2017-12-30 | 2017-12-12 |
| Pharmacogenetics Anomaly Research in Children and Adolescents With Pharmacological Resistance to Psychotropic Drugs gene abnormalities - Drug Resistance, Psychotropic Drugs | Not applicable | Completed | Fondation Lenval | 22 | 2016-12-07 | 2019-02-26 |
| Bacterial Transmission Dynamics Study Longitudinal surveillance study - Bacterial Transmission Surveillance, Neonatal Intensive Care Unit | Completed | University of Oxford | 97 | 2015-02-01 | 2019-09-11 | |
| Clinical Characteristics for the Critical Ill Patients With Klebsiella Pneumoniae Infection Drug Resistance | Completed | Fujian Provincial Hospital | 546 | 2015-01-01 | 2020-05-27 | |
| (18F)FCWAY and the Blood-Brain Barrier Drug Resistance | Completed | National Institute of Mental Health (NIMH) | 18 | 2011-06-15 | 2018-07-05 | |
| Aspirin and Clopidogrel Resistance Study Drug Resistance | Completed | University Hospital, Basel, Switzerland | 82 | 2010-05-01 | 2012-02-09 | |
| Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar First line antimalarial in Myanmar (artemether-lumefrantrine, dihydroartemisinin-piperaquine, and artesunate-mefloquine) - Drug Resistance, Plasmodium Falciparum Malaria | Completed | Department of Medical Research, Lower Myanmar | 550 | 2009-06-01 | 2016-06-08 | |
| Effect of Ceftobiprole on Human Intestinal Microflora Ceftobiprole - Antimicrobial Agent, Cephalosporins | Phase 1 | Completed | Basilea Pharmaceutica | 12 | 2009-04-01 | 2012-07-30 |
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Coronary Artery Disease (2) · Malaria, Falciparum (2) · Acute Coronary Syndrome (1) · Bacteremia (1) · Breast Neoplasms (1) · Carcinoma, Ovarian Epithelial (1) · Colorectal Neoplasms (1) · Critical Illness (1) · Diabetes Mellitus (1) · Dysbiosis (1) · Esophageal Neoplasms (1) · Infections (1) · Kidney Failure, Chronic (1) · Lung Neoplasms (1) · Medication Adherence (1)
Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Infections (4) · Neoplasms (4) · Neoplasms by Site (4) · Cardiovascular Diseases (3) · Disease Attributes (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Heart Diseases (3) · Myocardial Ischemia (3) · Urogenital Diseases (3) · Vascular Diseases (3) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2)
Aspirin (2) · Albendazole (1) · Artemether, Lumefantrine Drug Combination (1) · Cetuximab (1) · Eosinophil Peroxidase (1) · Erythropoietin (1) · Lamivudine (1) · Liquid Biopsy (1) · Mebendazole (1) · Pyrantel (1) · Rifaximin (1) · ceftobiprole (1) · dolutegravir (1) · doravirine (1)
University Heart Center Freiburg - Bad Krozingen (2) · University of Aarhus (2) · University of Oxford (2) · Basilea Pharmaceutica (1) · Centre de Recherche Médicale de Lambaréné (1) · Chuangzhen Chen (1) · Collegium Medicum w Bydgoszczy (1) · Department of Medical Research, Lower Myanmar (1) · Didier Menard (1) · Fondation Lenval (1) · Fujian Provincial Hospital (1) · Hunan Cancer Hospital (1) · Inha University Hospital (1) · Insel Gruppe AG, University Hospital Bern (1) · Konya Numune Hospital (1)
China (3) · Thailand (3) · Canada (2) · Denmark (2) · France (2) · Germany (2) · Switzerland (2) · Burma (1) · Ethiopia (1) · Gabon (1) · Poland (1) · South Korea (1) · Taiwan (1) · Turkey (Türkiye) (1) · United States (1)
Franz-Josef Neumann, MD (2) · Ben Cooper, Dr. (1) · Didier Menard, Professor (1) · Dimitrios Tsakiris, MD (1) · Direk Limmathurotsakul, MD, PhD (1) · Erik L Grove, MD (1) · Gilles Wandeler, Prof (1) · Jacek Kubica, Prof. (1)
PMID 17084243, PMID 18482659, PMID 20510210, PMID 20926263, PMID 21685174, PMID 24175592, PMID 25127973, PMID 25737147, PMID 26903338, PMID 27080992, PMID 28013264, PMID 28442293, PMID 28806957, PMID 29276050, PMID 29349545, PMID 29444952, PMID 30761114, PMID 31253124, PMID 31765385, PMID 32747827, PMID 34551228, PMID 37488448, PMID 37640962, PMID 37754284, PMID 38563751, PMID 39578038, PMID 40808656, PMID 41364144, PMID 41525016, PMID 42551453