3 recruiting, 1 active not recruiting, 1 terminated, 1 unknown. 6 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Recruiting 3, Active not recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 3 | Active not recruiting 1, Recruiting 1, Unknown 1 |
Follow DIPG: new trials by email Literature Review of DIPG trials Research Report on DIPG
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). BCB-276 - Diffuse Intrinsic Pontine Glioma, DIPG | Phase 2 | Recruiting | BrainChild Bio, Inc | 75 | 2026-09-04 | 2026-10-28 |
| Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). Olaparib; 177Lu-DOTATATE - Solid Tumor Cancer, Medulloblastoma | Phase 1 / Phase 2 | Recruiting | Fundación de investigación HM | 25 | 2024-09-20 | 2026-06-04 |
| A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma Bevacizumab Injection, Ultra-low-dose RT - DIPG | Phase 2 | Recruiting | Tata Memorial Centre | 40 | 2020-02-04 | 2025-04-11 |
| Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma Doxorubicin - Glioblastoma (GBM), DIPG | Phase 2 | Terminated | Meyer Children's Hospital IRCCS | 21 | 2016-02-01 | 2021-02-09 |
| Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma MDV9300 - DIPG | Phase 1 / Phase 2 | Unknown | Hadassah Medical Organization | 50 | 2014-02-01 | 2016-09-13 |
| A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas Mebendazole, Vincristine, Carboplatin - Pilomyxoid Astrocytoma, Pilocytic Astrocytoma | Phase 1 / Phase 2 | Active not recruiting | Julie Krystal | 10 | 2013-10-22 | 2026-08-06 |
Diffuse Intrinsic Pontine Glioma (3) · Glioblastoma (3) · Glioma (3) · Astrocytoma (2) · Adrenal Cortex Neoplasms (1) · Adrenal Gland Neoplasms (1) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Ependymoma (1) · Esthesioneuroblastoma, Olfactory (1) · Gliosarcoma (1) · Medulloblastoma (1) · Meningioma (1) · Neoplasms (1) · Neoplasms, Neuroepithelial (1)
Neoplasms by Histologic Type (4) · Neoplasms by Site (4) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Neuroectodermal Tumors (4) · Brain Diseases (3) · Brain Stem Neoplasms (3) · Central Nervous System Diseases (3) · Central Nervous System Neoplasms (3) · Infratentorial Neoplasms (3) · Neoplasms (3) · Neoplasms, Neuroepithelial (3)
Bevacizumab (2) · Carboplatin (1) · Doxorubicin (1) · Irinotecan (1) · Mebendazole (1) · Temozolomide (1) · Vincristine (1) · lutetium Lu 177 dotatate (1) · olaparib (1) · pidilizumab (1)
BrainChild Bio, Inc (1) · Fundación de investigación HM (1) · Hadassah Medical Organization (1) · Julie Krystal (1) · Meyer Children's Hospital IRCCS (1) · Tata Memorial Centre (1)
United States (2) · India (1) · Israel (1) · Italy (1) · Spain (1)
Cori Abikoff, MD (1) · Julie Krystal, MD (1) · Marta Osuna Marco, PhD (1) · Rahul Krishnatry, Dr (1)
2015 (1)