7 terminated, 5 completed, 1 unknown, 1 withdrawn. 12 Phase 2, 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Terminated 6, Completed 5, Unknown 1 |
| Phase 1 | 5 | Terminated 3, Unknown 1, Withdrawn 1 |
Follow pidilizumab: new trials by email Literature Review of pidilizumab trials Research Report on pidilizumab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pidilizumab in Treating Patients With Stage III-IV Diffuse Large B-Cell Lymphoma Following First Remission Laboratory Biomarker Analysis, Pidilizumab - Stage III Diffuse Large B-Cell Lymphoma, Stage IV Diffuse Large B-Cell Lymphoma | Phase 2 | Terminated | Northwestern University | 4 | 2015-09-01 | 2018-03-19 |
| Lenalidomide and Pidilizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma lenalidomide, pidilizumab, pharmacological study - Multiple Myeloma | Phase 1 | Terminated | Ohio State University Comprehensive Cancer Center | 20 | 2014-03-03 | 2023-01-27 |
| Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma MDV9300 - DIPG | Phase 1 / Phase 2 | Unknown | Hadassah Medical Organization | 50 | 2014-02-01 | 2016-09-13 |
| Sipuleucel-T, CT-011, and Cyclophosphamide for Advanced Prostate Cancer CT-011 (Anti-PD1 Antibody), Sipuleucel-T (Provenge), Cyclophosphamide - Prostatic Neoplasms | Phase 2 | Terminated | Augusta University | 7 | 2012-09-01 | 2019-07-10 |
| Gemcitabine and CT-011 for Resected Pancreatic Cancer CT-011, Gemcitabine - Pancreatic Neoplasms, Cancer of the Pancreas | Phase 2 | Terminated | Augusta University | 2 | 2012-09-01 | 2019-07-10 |
| Safety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic Melanoma CT-011 - Melanoma, Malignant Melanoma | Phase 2 | Completed | Medivation, Inc. | 103 | 2011-11-01 | 2016-01-21 |
| PD-1 Alone or With Dendritic Cell/Renal Cell Carcinoma Fusion Cell Vaccine CT-011, DC/RCC fusion vaccine - Renal Cell Carcinoma | Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 11 | 2011-11-01 | 2017-02-08 |
| CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors p53: 264-272 peptide, CT-011 - Breast Cancer, Colon Cancer | Phase 1 | Withdrawn | National Cancer Institute (NCI) | 2011-06-15 | 2017-07-02 | |
| Blockade of PD-1 in Conjunction With the Dendritic Cell/Myeloma Vaccines Following Stem Cell Transplantation CT-011, Dendritic Cell Fusion Vaccine - Multiple Myeloma | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 35 | 2010-03-01 | 2026-04-06 |
| Monoclonal Antibody CT-011 in Combination With Rituximab in Patients With Relapsed Follicular Lymphoma CT-011, Rituximab - Lymphoma | Phase 2 | Completed | M.D. Anderson Cancer Center | 32 | 2010-01-01 | 2016-06-03 |
| Safety and Tolerability Study of the Monoclonal Antibody CT-011 in Patients With Hepatocellular Carcinoma CT-011 - Primary Hepatocellular Carcinoma | Phase 1 / Phase 2 | Terminated | CureTech Ltd | 2 | 2009-10-01 | 2012-10-23 |
| Safety and Tolerability Study of the Monoclonal Antibody CT-011 in Patients With Chronic Hepatitis C Genotype I Infection CT-011 - Chronic Hepatitis C | Phase 1 / Phase 2 | Terminated | CureTech Ltd | 13 | 2009-09-01 | 2014-08-29 |
| Study to Evaluate the Safety, Tolerability and Efficacy of FOLFOX + CT-011 Versus FOLFOX Alone CT-011, FOLFOX - Metastatic Colorectal Cancer | Phase 2 | Completed | Medivation, Inc. | 171 | 2009-05-01 | 2015-07-08 |
| CT-011 MAb in DLBCL Patients Following ASCT CT-011 - Lymphoma, Large Cell, Diffuse, Lymphoma, Mixed Cell, Diffuse | Phase 2 | Completed | CureTech Ltd | 72 | 2007-10-01 | 2014-09-12 |
Lymphoma, Large B-Cell, Diffuse (2) · Multiple Myeloma (2) · Pancreatic Neoplasms (2) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Hepatitis C, Chronic (1) · Liver Diseases (1) · Lymphoma (1) · Lymphoma, Follicular (1) · Lymphoma, Non-Hodgkin (1) · Melanoma (1) · Neoplasm Metastasis (1)
CureTech Ltd (3) · Augusta University (2) · Beth Israel Deaconess Medical Center (2) · Medivation, Inc. (2) · Hadassah Medical Organization (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1) · Northwestern University (1) · Ohio State University Comprehensive Cancer Center (1)
United States (11) · Israel (6) · India (2) · Bulgaria (1) · Peru (1) · Puerto Rico (1) · Romania (1)
David Avigan, MD (2) · Samir N. Khleif, MD (2) · Yaron Ilan, MD (2) · Arnon Nagler, MD (1) · Jane Winter, MD (1) · Leo I Gordon, MD (1) · Leonard B Saltz, MD (1) · Michael B. Atkins, M.D. (1) · Sattva S. Neelapu, MD (1) · Yvonne Efebera (1)
2009 (1), P30CA060553 (1), P50CA101942 (1)