7 not yet recruiting, 5 completed, 4 recruiting, 3 active not recruiting. 8 Phase 2, 7 Not applicable, 2 Phase 1.
Follow Diabetic Kidney Disease (DKD): new trials by email Literature Review of Diabetic Kidney Disease (DKD) trials Research Report on Diabetic Kidney Disease (DKD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD) Early goal-directed Cardio-Kidney-Metabolic (CKM) care, Standard care (Comparison arm) - Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM) | Not applicable | Recruiting | Sunnybrook Health Sciences Centre | 100 | 2026-08-26 | 2026-09-04 |
| The Relationship Between Psychological Well-being, Social Support, and Disease Self-management in Patients With Diabetic Nephropathy Diabetic Kidney Disease (DKD), Type 2 Diabetes | Not yet recruiting | National Taiwan University Hospital | 161 | 2026-08-07 | 2026-07-24 | |
| Mechanisms Underlying SGLT2i Kidney Effect in DKD Progression MRI - Diabetic Kidney Disease (DKD) | Not applicable | Not yet recruiting | Mario Negri Institute for Pharmacological Research | 100 | 2026-02-01 | 2025-12-08 |
| Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease ALN-ANG3, Evinacumab, Placebo - Diabetic Kidney Disease (DKD) | Phase 2 | Recruiting | Regeneron Pharmaceuticals | 195 | 2026-01-09 | 2026-10-27 |
| Finerenone for Cardiorenal Protection in Diabetic CKD: Impact on Renal Function Decline and Heart Failure Finerenone - Diabetic Kidney Disease (DKD), Heart Failure | Not applicable | Not yet recruiting | College of Physicians and Surgeons Pakistan | 120 | 2026-01-01 | 2026-01-08 |
| Mesenchymal Stem Cells for Chronic Kidney Diseases 0.9% sodium chloride, MSCs - Kidney Disease, Chronic, Diabetic Kidney Disease (DKD) | Phase 1 / Phase 2 | Not yet recruiting | The First Affiliated Hospital of Air Force Medicial University | 32 | 2026-01-01 | 2025-12-24 |
| Rubix LS Diabetic Kidney Disease (DKD) Registry Study Kidney-Protective Therapies Used in Routine Care - Diabetic Kidney Disease (DKD) | Active not recruiting | Rubix LS | 2000 | 2025-12-15 | 2026-01-16 | |
| A Study on the Safety and Clinical Efficacy of Guominkang in the Treatment of Diabetic Kidney Disease Guominkang Granules, Standard Antihypertensive, Antidiabetic, and Lipid-Lowering Regimen - Diabetic Kidney Disease (DKD), Type 2 Diabetes | Phase 2 | Active not recruiting | Beijing University of Chinese Medicine | 15 | 2025-10-20 | 2026-11-02 |
| YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study2 the traditional Chinese medicine prescription ' Shenzhuo Decoction ', basic treatment - Diabetic Kidney Disease (DKD) | Not applicable | Not yet recruiting | Liu Hongfang | 228 | 2025-08-01 | 2025-06-24 |
| YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study1 Diabetic Kidney Disease (DKD) | Not yet recruiting | Liu Hongfang | 4472 | 2025-08-01 | 2025-06-22 | |
| Safety and Efficacy of Mesenchymal Stromal Cells (Amimestrocel ) in Diabetic Kidney Disease Amimestrocel - Diabetic Kidney Disease (DKD) | Phase 2 | Recruiting | Chinese PLA General Hospital | 120 | 2025-06-09 | 2026-07-14 |
| Efficacy and Safety Study of Isuzinaxib in Subjects With DKD Isuzinaxib, Placebo - Diabetic Kidney Disease (DKD) | Phase 2 | Recruiting | Aptabio Therapeutics, Inc. | 186 | 2025-05-26 | 2025-07-18 |
| Remote Ischemic Conditioning for the Treatment of Diabetic Kidney Disease Remote ischemic conditioning, Sham remote ischemic conditioning, Standard medication therapy - Diabetic Kidney Disease (DKD) | Not applicable | Not yet recruiting | Capital Medical University | 60 | 2025-01-01 | 2024-10-23 |
| Safety and Efficacy of the Combination Therapy of Fucoidan / Fucoxanthin / L-carnitine in Patients With Diabetic Nephropathy. Oligo-fucoidan, Fucoxanthin, L-carnitine Formula, Zinc yeast (FFL) - Diabetic Kidney Disease (DKD) | Phase 2 | Completed | Taipei Medical University WanFang Hospital | 63 | 2024-11-06 | 2026-09-04 |
| Preliminary Study of CXCL3 As a Biomarker of Diabetic Kidney Disease Tests of the expression of CXCL3 in various tissues - Diabetic Kidney Disease (DKD) | Not applicable | Completed | The First Hospital of Jilin University | 120 | 2024-06-10 | 2024-10-15 |
| Autologous Dendritic Cell as Adjunct Therapy for Diabetic Kidney Disease Dendritic cell immunotherapy - Diabetic Kidney Disease (DKD) | Phase 1 / Phase 2 | Active not recruiting | PT. JES Kasih Nusantara Sejahterah | 80 | 2024-05-01 | 2025-12-05 |
| ALLOPURINOL AND LISINOPRIL FOR DIABETIC KIDNEY PROTECTION: A COMPARATIVE STUDY IN NORMOURICEMIC TYPE 2 DIABETICS Allopurinol - Diabetic Kidney Disease (DKD) | Not applicable | Completed | Narowal Medical College | 80 | 2023-05-14 | 2025-09-17 |
| Establishment of the Human Intestinal and Salivary Microbiota Biobank - Kidney Diseases Biological sample collection, Questionnaire, Medical examination - Autosomal Dominant Polycystic Kidney Disease (ADPKD), Advanced-Chronic Kidney Disease (CKD) | Completed | Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari | 150 | 2021-02-03 | 2022-08-01 | |
| Vascular Endothelial Growth Factor-B (VEGF-B) Blockade With the Monoclonal Antibody CSL346 in Subjects With Diabetic Kidney Disease CSL346, Placebo - Diabetic Kidney Disease (DKD) | Phase 2 | Completed | CSL Behring | 114 | 2020-09-14 | 2023-12-06 |
Diabetic Nephropathies (19) · Diabetes Mellitus, Type 2 (5) · Renal Insufficiency, Chronic (5) · Albuminuria (3) · Diabetes Mellitus (1) · Glomerulonephritis, IGA (1) · Heart Failure (1) · Hypertensive Nephropathy (1) · Polycystic Kidney, Autosomal Dominant (1) · Psychological Well-Being (1) · Renal Insufficiency (1)
Diabetes Complications (19) · Endocrine System Diseases (19) · Female Urogenital Diseases (19) · Female Urogenital Diseases and Pregnancy Complications (19) · Kidney Diseases (19) · Male Urogenital Diseases (19) · Urogenital Diseases (19) · Urologic Diseases (19) · Diabetes Mellitus (18) · Pathological Conditions, Signs and Symptoms (7) · Chronic Disease (5) · Disease Attributes (5) · Glucose Metabolism Disorders (5) · Metabolic Diseases (5) · Nutritional and Metabolic Diseases (5)
Allopurinol (1) · Control Groups (1) · Creatine Kinase, MM Form (1) · Hypoglycemic Agents (1) · Independent Medical Evaluation (1) · Sodium Chloride (1) · Standard of Care (1) · Surveys and Questionnaires (1) · evinacumab (1) · finerenone (1) · fucoxanthin (1) · isuzinaxib (1)
Liu Hongfang (2) · Aptabio Therapeutics, Inc. (1) · Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari (1) · Beijing University of Chinese Medicine (1) · CSL Behring (1) · Capital Medical University (1) · Chinese PLA General Hospital (1) · College of Physicians and Surgeons Pakistan (1) · Mario Negri Institute for Pharmacological Research (1) · Narowal Medical College (1) · National Taiwan University Hospital (1) · PT. JES Kasih Nusantara Sejahterah (1) · Regeneron Pharmaceuticals (1) · Rubix LS (1) · Sunnybrook Health Sciences Centre (1)
China (5) · United States (3) · Canada (2) · Italy (2) · Taiwan (2) · Australia (1) · Indonesia (1) · Israel (1) · New Zealand (1) · Pakistan (1) · Puerto Rico (1) · South Korea (1)
HongFang Liu (2) · Giuseppe Remuzzi, M.D. (1) · Loreto Gesualdo, MD (1) · Reginald Swift (1)
PMID 39150859, PMID 39727944, PMID 39727950, PMID 39727989, PMID 39852146, PMID 40903083