5 completed, 4 not yet recruiting, 3 recruiting, 2 unknown. 7 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 3, Not yet recruiting 3, Recruiting 1 |
Follow Deterioration, Clinical: new trials by email Literature Review of Deterioration, Clinical trials Research Report on Deterioration, Clinical
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration Training Generative AI-integrated Blended Simulation, High Fidelity Simulation - Clinical Reasoning in Nursing Education, Virtual Simulation | Not applicable | Not yet recruiting | National University of Singapore | 200 | 2026-10-12 | 2026-10-21 |
| Hospital-Onset Sepsis Systematic Detection and Structured Interventions Algorithm-triggered sepsis alert with structured critical care team activation - Sepsis, Deterioration, Clinical | Not applicable | Not yet recruiting | Patricks Lyons | 3700 | 2026-10-01 | 2026-09-04 |
| Cognitive Outcomes in BAD-related Stroke END exposure - Branch Atheromatous Disease, Cognitive | Not yet recruiting | Peking Union Medical College Hospital | 60 | 2026-09-01 | 2026-08-12 | |
| Optimized Novel Wireless Assessment of Respiratory and Circulatory Dirstress - Alarm Validation Continuous vital sign monitoring - Postoperative Care, Deterioration, Clinical | Not applicable | Not yet recruiting | Eske Kvanner Aasvang | 100 | 2026-05-28 | 2026-06-16 |
| Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission Home-based Clinical Assessment and Treatment - Nursing Homes Residents, Deterioration, Clinical | Not applicable | Recruiting | Copenhagen University Hospital at Herlev | 9000 | 2026-02-01 | 2026-09-02 |
| VitalThings Guardian Contactless Monitoring Vitalthings Guardian M10 fixed and M10 mobile - Respiratory Depression, Respiratory Failure | Completed | VitalThings | 41 | 2023-11-15 | 2023-12-05 | |
| Observational Study of Early Postoperative Deterioration and Complications Postoperative Complications, Deterioration, Clinical | Completed | Copenhagen University Hospital, Hvidovre | 240 | 2023-10-03 | 2026-01-21 | |
| Feasibility and Initial Clinical Impressions of Predictive Monitoring Integrated With the RACE Team Visensia Safety Index (VSI) - Deterioration, Clinical | Not applicable | Completed | Ottawa Hospital Research Institute | 41 | 2023-09-19 | 2026-09-08 |
| vHDU Phase 5: Impact of an Ambulatory Monitoring System on Deterioration Detection and Clinical Outcomes Ambulatory monitoring system, Active alerting system - Surgery, Deterioration, Clinical | Not applicable | Completed | University of Oxford | 240 | 2022-07-28 | 2026-02-23 |
| Automated Alerts of Patient Deterioration vs. Routine Monitoring of High-risk Patients Admitted to Medical Wards real time alarm of deviating vital signs - Alert Fatigue, Health Personnel, Deterioration, Clinical | Not applicable | Completed | University Hospital Bispebjerg and Frederiksberg | 300 | 2022-01-07 | 2025-04-11 |
| A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using CTPA. Pulmonary Embolism and Thrombosis, Deterioration, Clinical | Recruiting | Shengjing Hospital | 300 | 2021-01-18 | 2026-03-11 | |
| Outcomes of Digital Alerting Systems in Secondary Care SensiumVitals wearable patch sensor - Sepsis, Deterioration, Clinical | Unknown | Imperial College London | 650 | 2017-10-01 | 2020-11-20 | |
| Early Neurological Deterioration in Recent Small Subcortical Infarction no intervention - Cerebral Infarction, Subcortical Infarction | Unknown | Yuan Gao | 1000 | 2015-01-01 | 2023-09-01 | |
| Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography no intervention - Pulmonary Embolism and Thrombosis, Deterioration, Clinical | Recruiting | Shengjing Hospital | 2000 | 2011-01-01 | 2026-03-11 | |
| An Observational Study About Adverse Outcomes in Acute Pulmonary Embolism Patients retrospective observational study - Pulmonary Embolism and Thrombosis, Deterioration, Clinical | Active not recruiting | Shengjing Hospital | 2000 | 2011-01-01 | 2026-03-11 |
Clinical Deterioration (15) · Pulmonary Embolism (3) · Thrombosis (3) · Sepsis (2) · Agnosia (1) · Alert Fatigue, Health Personnel (1) · Cerebral Infarction (1) · Critical Illness (1) · Dehydration (1) · Disease Progression (1) · Infections (1) · Postoperative Complications (1) · Respiratory Insufficiency (1)
Disease Attributes (15) · Pathologic Processes (15) · Pathological Conditions, Signs and Symptoms (15) · Disease Progression (14) · Cardiovascular Diseases (4) · Respiratory Tract Diseases (4) · Vascular Diseases (4) · Embolism (3) · Embolism and Thrombosis (3) · Lung Diseases (3) · Infections (2) · Inflammation (2) · Nervous System Diseases (2) · Signs and Symptoms (2) · Systemic Inflammatory Response Syndrome (2)
Therapeutics (1)
Shengjing Hospital (3) · Copenhagen University Hospital at Herlev (1) · Copenhagen University Hospital, Hvidovre (1) · Eske Kvanner Aasvang (1) · Imperial College London (1) · National University of Singapore (1) · Ottawa Hospital Research Institute (1) · Patricks Lyons (1) · Peking Union Medical College Hospital (1) · University Hospital Bispebjerg and Frederiksberg (1) · University of Oxford (1) · VitalThings (1) · Yuan Gao (1)
China (5) · Denmark (4) · United Kingdom (2) · Canada (1) · Norway (1) · United States (1)
Andrew JE Seely, MD, PhD, FRCSC (1) · Eske K Aasvang, MD,Med.Sc.D. (1) · Kasper K Iversen, MD, Professor (1) · Lea B Hvidberg, RN, Ms.c. (1) · Line Pedersen, MD, Phd (1) · Martin G Tolsgaard, MD,Med.Sc.D. (1) · Meera Joshi, MRCS, PhD (1) · Nicolai B Foss, MD,Med.Sc.D. (1) · Peter Watkinson, MD (1) · Shengde Li, MD (1) · Yuan Gao, doctor (1)
PMID 33944790, PMID 35794669, PMID 35832414, PMID 39665054, PMID 40576035, PMID 40742731, PMID 41174707, PMID 41804675