13 completed, 2 not yet recruiting, 1 active not recruiting, 1 recruiting. 14 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 11, Active not recruiting 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Completed 2 |
Follow Delayed Onset Muscle Soreness (DOMS): new trials by email Literature Review of Delayed Onset Muscle Soreness (DOMS) trials Research Report on Delayed Onset Muscle Soreness (DOMS)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Real-world Evidence of Cannabinoid for Observed Pain Relief Chronic Musculoskeletal Pain, Delayed Onset Muscle Soreness (DOMS) | Not yet recruiting | Associação Pan-Americana Multidisciplinar de Endocanabinologia | 60 | 2027-01-01 | 2026-07-30 | |
| Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise Pulsed Low-Intensity Therapeutic Ultrasound, Placebo Therapeutic Ultrasound - Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS) | Not applicable | Not yet recruiting | Universidade Federal de Santa Maria | 30 | 2026-11-01 | 2026-10-13 |
| Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women Curcumin, Ibuprofen, Placebo - Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | University of Valladolid | 36 | 2026-08-22 | 2026-09-23 |
| Effectiveness of Instrument-Assisted Soft Tissue Mobilization (IASTM) and Myofascial Release in Reducing Delayed Onset Muscle Soreness (DOMS) in the Cervicothoracic Region IASTM, MFR - Delayed Onset Muscle Soreness (DOMS), Muscle Soreness | Not applicable | Completed | Green International University | 58 | 2026-04-06 | 2026-05-27 |
| Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness Lactobacillus casei, Placebo Capsule(s) - Exercise Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS) | Not applicable | Recruiting | University of Minnesota | 24 | 2026-02-05 | 2026-05-04 |
| Isometric Exercise for Delayed Onset Muscle Soreness Isometric Exercise, Sham Exercise - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Istanbul Nisantasi University | 40 | 2025-04-01 | 2026-06-16 |
| Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion Cold Therapy with Axanova Cold Hot Pearls Maxi Pack - Delayed Onset Muscle Soreness (DOMS), Inflammation | Not applicable | Completed | University of Applied Sciences and Arts of Southern Switzerland | 48 | 2025-03-17 | 2026-03-04 |
| A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults SpecioTea, MitraPlex, Placebo - Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness | Phase 2 | Completed | Traditional Naturals Research Inc. | 100 | 2025-02-05 | 2026-09-09 |
| Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise Eccentric resistance exercise - Exercise Induced Muscle Damage, Physical Activity | Not applicable | Active not recruiting | University of Toronto | 16 | 2025-01-24 | 2025-02-05 |
| PNF Versus Cryotherapy in Delayed Onset Muscle Soreness Proprioceptive Neuromuscular Facilitation, Local Cryotherapy, Placebo: Water With Sugar - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Universidad Pontificia de Salamanca | 29 | 2025-01-01 | 2026-06-16 |
| The Effect of Percussion Massage Therapy on the Recovery of DOMS in Physically Active Young Men Delayed Onset Muscle Soreness = DOMS Static stretching, Fascia gun ( Short-time PMT ), Fascia gun ( Long-time PMT ) - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Shanxi Normal University | 30 | 2024-07-01 | 2024-09-25 |
| Comparison of the Effects of Kinesio Taping and Graston Application in Individuals With Delayed Onset Muscle Soreness kinesio taping, Graston Technique - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Gazi University | 36 | 2024-06-20 | 2026-08-13 |
| Effects of Sports Massage and Thai Massage on Delayed-Onset Muscle Soreness and Recovery Sports Massage, Traditional Thai Massage, Passive Recovery - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Akdeniz University | 35 | 2023-12-11 | 2026-10-23 |
| Vibrating and Non-Vibrating Foam-Rolling on DOMS Vibrating Foam Rolling, Non-Vibrating Foam Rolling - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Hacettepe University | 30 | 2023-01-01 | 2026-10-20 |
| Posterior Chain Responses to Gastrocnemius DOMS Gastrocnemius DOMS Induction Protocol - Delayed Onset Muscle Soreness (DOMS), Healthy | Not applicable | Completed | Ebru Aloğlu Çiftçi | 14 | 2022-12-20 | 2026-01-07 |
| Photobiomodulation on NMES-Induced Muscle Fatigue and Damage Photobiomodulation Therapy (PBMT), Sham Photobiomodulation - Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Federal University of Rio Grande do Sul | 12 | 2022-11-01 | 2026-08-31 |
| Study to Assess the Safety, Tolerability, and Effects of CHI-202 to Support Recovery From Physical Activity CHI-202, CHI-101 - Delayed Onset Muscle Soreness (DOMS) | Phase 2 | Completed | Canopy Growth Corporation | 40 | 2021-12-13 | 2022-02-16 |
Inflammation (4) · Myalgia (3) · Pain (2) · Motor Activity (1)
Pathological Conditions, Signs and Symptoms (7) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Pathologic Processes (4) · Muscular Diseases (3) · Musculoskeletal Diseases (3) · Musculoskeletal Pain (3) · Nervous System Diseases (3) · Neuromuscular Diseases (3) · Pain (3) · Behavior (1)
Muscle Stretching Exercises (2) · Cryotherapy (1) · Curcumin (1) · Exercise (1) · Ibuprofen (1) · Low-Level Light Therapy (1) · Medicine, Thai Traditional (1) · Sugars (1) · turmeric extract (1)
Akdeniz University (1) · Associação Pan-Americana Multidisciplinar de Endocanabinologia (1) · Canopy Growth Corporation (1) · Ebru Aloğlu Çiftçi (1) · Federal University of Rio Grande do Sul (1) · Gazi University (1) · Green International University (1) · Hacettepe University (1) · Istanbul Nisantasi University (1) · Shanxi Normal University (1) · Traditional Naturals Research Inc. (1) · Universidad Pontificia de Salamanca (1) · Universidade Federal de Santa Maria (1) · University of Applied Sciences and Arts of Southern Switzerland (1) · University of Minnesota (1)
Turkey (Türkiye) (5) · Brazil (2) · Canada (2) · Spain (2) · United States (2) · China (1) · Pakistan (1) · Switzerland (1)
Erica Peters, PhD (1) · Gulcan Harput (1) · Marco A Vaz, PhD (1) · Mary Stenson (1) · Ron Clijsen, Prof. Dr. (1)
PMID 29373060, PMID 30865998, PMID 32396966, PMID 33768777, PMID 40206177, PMID 42512191