90 completed, 26 terminated, 5 withdrawn, 4 unknown. 52 Phase 2, 37 Phase 1, 19 Not applicable, 15 Phase 3, 2 Early Phase 1.
Follow Chronic Myeloproliferative Disorders: new trials by email Literature Review of Chronic Myeloproliferative Disorders trials Research Report on Chronic Myeloproliferative Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Pulmonary Hypertension in Patients With Chronic Myeloproliferative Disorders at Sohag University Hospital Echocardiography - Chronic Myeloproliferative Disorders | Unknown | Sohag University | 150 | 2021-05-01 | 2021-04-15 | |
| Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies Fludarabine, Cyclophosphamide, Total body irradiation - Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 117 | 2015-12-01 | 2022-11-03 |
| Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease anti-thymocyte globulin, sargramostim, therapeutic allogeneic lymphocytes - Chronic Myeloproliferative Disorders, Leukemia | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 71 | 2011-01-07 | 2017-05-30 |
| INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease ruxolitinib phosphate, laboratory biomarker analysis, pharmacological study - Chronic Myeloproliferative Disorders, Leukemia | Phase 1 | Completed | Children's Oncology Group | 49 | 2010-09-01 | 2014-10-23 |
| Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation anti-thymocyte globulin, rituximab, sirolimus - Chronic Myeloproliferative Disorders, Graft Versus Host Disease | Phase 2 | Terminated | Barbara Ann Karmanos Cancer Institute | 4 | 2010-08-01 | 2019-03-26 |
| Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome Lactobacillus rhamnosus GG - Breast Cancer, Chronic Myeloproliferative Disorders | Not applicable | Terminated | Rutgers, The State University of New Jersey | 30 | 2010-03-01 | 2017-02-03 |
| Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell Transplant DNA analysis, polymerase chain reaction, flow cytometry - Cancer Survivor, Chronic Myeloproliferative Disorders | Terminated | Vanderbilt University | 24 | 2010-02-01 | 2014-12-10 | |
| Registry of Older Patients With Cancer Chronic Myeloproliferative Disorders, Cognitive/Functional Effects | Recruiting | UNC Lineberger Comprehensive Cancer Center | 3000 | 2009-09-01 | 2026-06-29 | |
| 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer 3'-deoxy-3'-[18F]fluorothymidine - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Active not recruiting | Barbara Ann Karmanos Cancer Institute | 2009-09-01 | 2026-08-10 | ||
| Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer biologic sample preservation procedure, cytology specimen collection procedure - Chronic Myeloproliferative Disorders, Leukemia | Recruiting | UNC Lineberger Comprehensive Cancer Center | 15000 | 2009-07-01 | 2025-10-27 | |
| Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer methadone hydrochloride, morphine sulfate, oxycodone hydrochloride - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Not applicable | Terminated | M.D. Anderson Cancer Center | 1 | 2009-03-01 | 2020-09-24 |
| Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer donor natural killer cell infusion - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Phase 1 / Phase 2 | Completed | Asan Medical Center | 47 | 2009-01-01 | 2013-02-20 |
| Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone chemotherapy, dapsone, medical chart review - Chronic Myeloproliferative Disorders, Leukemia | Completed | Vanderbilt University | 41 | 2009-01-01 | 2017-04-17 | |
| Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment fludarabine phosphate, melphalan, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Chronic Myeloproliferative Disorders, Leukemia | Phase 1 | Terminated | City of Hope Medical Center | 6 | 2008-11-01 | 2015-06-08 |
| Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers cytology specimen collection procedure, fluorescent antibody technique, assessment of therapy complications - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Not applicable | Terminated | City of Hope Medical Center | 9 | 2008-11-01 | 2015-06-08 |
| American Ginseng in Treating Patients With Fatigue Caused by Cancer American ginseng, placebo - Chronic Myeloproliferative Disorders, Fatigue | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 364 | 2008-10-01 | 2017-02-09 |
| Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorder cyclosporine ophthalmic emulsion, placebo - Chronic Myeloproliferative Disorders, Graft Versus Host Disease | Phase 3 | Completed | Vanderbilt-Ingram Cancer Center | 164 | 2008-10-01 | 2017-03-07 |
| Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer cyclosporine, mycophenolate mofetil, pentostatin - Chronic Myeloproliferative Disorders, Leukemia | Phase 1 / Phase 2 | Withdrawn | University of Nebraska | 2008-09-01 | 2023-08-14 | |
| Blood Samples From Patients on a Clinical Trial to CINV During HSCT immunoenzyme technique, laboratory biomarker analysis, medical chart review - Breast Cancer, Chronic Myeloproliferative Disorders | Terminated | OHSU Knight Cancer Institute | 9 | 2008-08-01 | 2017-05-09 | |
| Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases immunosuppressive therapy, immunological diagnostic method, allogeneic hematopoietic stem cell transplantation - Chronic Myeloproliferative Disorders, Graft Versus Host Disease | Terminated | City of Hope Medical Center | 60 | 2008-06-01 | 2011-03-07 |
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Myeloproliferative Disorders (129) · Primary Myelofibrosis (119) · Leukemia (118) · Myelodysplastic Syndromes (111) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (105) · Lymphoma (103) · Leukemia, Lymphocytic, Chronic, B-Cell (102) · Multiple Myeloma (101) · Neoplasms, Plasma Cell (97) · Burkitt Lymphoma (96) · Leukemia, Myeloid, Acute (96) · Lymphoma, Follicular (95) · Lymphoma, Mantle-Cell (94) · Lymphoma, Large B-Cell, Diffuse (93) · Lymphoma, Large-Cell, Immunoblastic (93)
Bone Marrow Diseases (129) · Hematologic Diseases (129) · Hemic and Lymphatic Diseases (129) · Neoplasms (121) · Neoplasms by Histologic Type (121) · Hemorrhagic Disorders (120) · Pathological Conditions, Signs and Symptoms (116) · Chronic Disease (115) · Disease Attributes (115) · Immune System Diseases (115) · Pathologic Processes (115) · Immunoproliferative Disorders (113) · Leukemia, Myeloid (113) · Lymphatic Diseases (111) · Leukemia, Lymphoid (106)
Cyclophosphamide (35) · Peripheral Blood Stem Cell Transplantation (31) · fludarabine phosphate (28) · Busulfan (24) · Tacrolimus (21) · Antilymphocyte Serum (18) · Cyclosporine (17) · Methotrexate (17) · Filgrastim (16) · Mycophenolic Acid (13) · Methylprednisolone (12) · Radiotherapy (12) · Etoposide (11) · Whole-Body Irradiation (10) · Melphalan (8)
Fred Hutchinson Cancer Center (12) · City of Hope Medical Center (8) · Case Comprehensive Cancer Center (7) · OHSU Knight Cancer Institute (7) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (6) · Alliance for Clinical Trials in Oncology (5) · Mayo Clinic (5) · Barbara Ann Karmanos Cancer Institute (4) · H. Lee Moffitt Cancer Center and Research Institute (4) · National Institutes of Health Clinical Center (CC) (4) · Northwestern University (4) · UNC Lineberger Comprehensive Cancer Center (4) · Vanderbilt-Ingram Cancer Center (4) · Memorial Sloan Kettering Cancer Center (3) · National Cancer Institute (NCI) (3)
United States (116) · Canada (3) · France (3) · Australia (1) · Belgium (1) · Germany (1) · Israel (1) · Italy (1) · New Zealand (1) · Saudi Arabia (1) · Slovakia (1) · South Korea (1) · Switzerland (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Ruben A. Mesa, MD (4) · Brian J. Bolwell, MD (3) · Philip L. McCarthy, MD (3) · Charles A. Linker, MD (2) · Debra Barton, RN, PhD, AOCN, FAAN (2) · H. Joachim Deeg, MD (2) · Joseph Bubalo, PharmD, BCPS, BCOP (2) · Madan Jagasia, MD (2) · Richard K. Burt, MD (2) · Richard Maziarz, MD (2) · Roger Strair, MD, PhD (2) · Steven C. Goldstein, MD (2) · Teresa Field, MD, PhD (2) · Thomas C. Shea, MD (2) · Thomas G. Martin, MD (2)
PMID 11468154, PMID 15466923, PMID 15570084, PMID 17397698, PMID 17562873, PMID 20124511, PMID 20496177, PMID 21479990, PMID 21719601, PMID 22157574, PMID 23358983, PMID 24530972, PMID 26175532, PMID 26210442, PMID 26700120, PMID 26700123, PMID 28935847, PMID 30205939, PMID 36999619, PMID 9326205
P30CA033572 (9), P30CA068485 (6), P30CA006973 (5), P30CA015083 (5), P30CA043703 (5), P01CA015396 (4), P30CA016086 (4), P30CA022453 (4), P30CA072720 (4), P30CA016058 (2), P30CA069533 (2), P01HL048546 (1), P30CA014520 (1), P30CA016087 (1), P30CA023074 (1)