7 completed, 3 unknown, 2 recruiting, 2 terminated. 7 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 4, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Chromosome Abnormality: new trials by email Literature Review of Chromosome Abnormality trials Research Report on Chromosome Abnormality
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies Fludarabine, Busulfan, Melphalan - Hematologic Malignancy, Acute Leukemia | Phase 2 | Recruiting | Masonic Cancer Center, University of Minnesota | 70 | 2023-05-11 | 2026-04-06 |
| Biocollection in MyeloDysplastic Syndrome (P-MDS) description of MDS pzatient cohort - Myelodysplastic Syndromes, Myelodysplastic Anemia | Not applicable | Recruiting | University Hospital, Brest | 150 | 2022-10-19 | 2026-06-25 |
| Invasive PGT-A Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection embryo selection - Infertility, Aneuploidy | Unknown | Assisting Nature | 200 | 2022-10-01 | 2022-09-21 | |
| Time Lapse Assisted Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection embryo selection - Infertility, Aneuploidy | Unknown | Assisting Nature | 200 | 2022-10-01 | 2022-09-28 | |
| RCT Study to Validate niPGT-A Clinical Benefit. niPGT-A, Morphology criteria - Aneuploidy, Chromosome Abnormality | Not applicable | Terminated | Igenomix | 296 | 2020-06-29 | 2025-10-01 |
| Embryo Selection by Noninvasive Preimplantation Genetic Test Non-invasive chromosome screening（NICS） - Infertility, Chromosome Abnormality | Not applicable | Completed | Peking University Third Hospital | 1152 | 2020-04-16 | 2025-12-11 |
| Structural Chromosome Rearrangements and Brain Disorders Rare Diseases, Genetic Disease | Enrolling by invitation | Karolinska Institutet | 10000 | 2019-12-20 | 2025-09-04 | |
| Validation of a NICS Method Using the Culture Medium Noninvasive chromosome screening - Chromosome Abnormality, Abnormality | Completed | Instituto Bernabeu | 50 | 2019-02-01 | 2020-08-10 | |
| North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 Pre-visit prep, usual care + exome seq - Epilepsy; Seizure, Neuromuscular Diseases | Not applicable | Completed | University of North Carolina, Chapel Hill | 548 | 2018-09-28 | 2025-05-13 |
| Clinical Value of Mosaicism Diagnosis on the Trophectoderm Biopsies PGT-A - Aneuploidy, Chromosome Abnormality | Completed | Igenomix | 783 | 2018-09-03 | 2020-10-19 | |
| Multi-center Study to Validate niPGT-A PGT-A, niPGT-A - Aneuploidy, Chromosome Abnormality | Completed | Igenomix | 2586 | 2018-04-27 | 2023-05-24 | |
| Efficacy of Counseling for Prenatal Screening and Diagnostic Tests on Pregnant Women: Randomised Controlled Study Prenatal Genetic Counseling - Decision Making, Chromosome Abnormality | Not applicable | Completed | Saglik Bilimleri Universitesi Gulhane Tip Fakultesi | 260 | 2017-06-10 | 2019-02-01 |
| Post-operative Lite Run Study Lite Run Gait Trainer, Usual Treatments - Cerebral Palsy, Neurologic Disorder | Not applicable | Completed | Gillette Children's Specialty Healthcare | 10 | 2017-05-15 | 2021-02-21 |
| Prenatal Screening, Diagnosis and Intrauterine Intervention of Fetal Abnormal Chromosome and Structure in Twins Pregnancy Fetal Selective Reduction Technology, Potassium Chloride - Chromosome Abnormality, Twin Pregnancy With Antenatal Problem | Not applicable | Unknown | Shanghai First Maternity and Infant Hospital | 1300 | 2017-01-01 | 2016-12-05 |
| Chromosome Abnormalities in Chronic Myeloid Leukemia (CML) on Imatinib. GIST Patients on Imatinib bone marrow aspiration - Chronic Myeloid Leukemia, Gastrointestinal Stromal Cell Tumors | Phase 4 | Terminated | University Health Network, Toronto | 68 | 2005-02-01 | 2009-02-13 |
Chromosome Aberrations (15) · Aneuploidy (5) · Infertility (5) · Congenital Abnormalities (2) · Genetic Diseases, Inborn (2) · Abortion, Spontaneous (1) · Anemia, Refractory, with Excess of Blasts (1) · Anxiety Disorders (1) · Autism Spectrum Disorder (1) · Behavior (1) · Cerebral Palsy (1) · Chromosome 5q Deletion Syndrome (1) · Chromosome 7, monosomy (1) · Disease (1) · Epilepsy (1)
Pathologic Processes (15) · Pathological Conditions, Signs and Symptoms (15) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Genital Diseases (5) · Urogenital Diseases (5) · Bone Marrow Diseases (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Disease Attributes (2) · Leukemia (2) · Leukemia, Myeloid (2) · Mental Disorders (2) · Neoplasms (2)
Busulfan (1) · Counseling (1) · Cyclophosphamide (1) · Genetic Counseling (1) · Levetiracetam (1) · Melphalan (1) · Potassium Chloride (1) · Rituximab (1) · fludarabine (1) · thymoglobulin (1)
Igenomix (3) · Assisting Nature (2) · Gillette Children's Specialty Healthcare (1) · Instituto Bernabeu (1) · Karolinska Institutet (1) · Masonic Cancer Center, University of Minnesota (1) · Peking University Third Hospital (1) · Saglik Bilimleri Universitesi Gulhane Tip Fakultesi (1) · Shanghai First Maternity and Infant Hospital (1) · University Health Network, Toronto (1) · University Hospital, Brest (1) · University of North Carolina, Chapel Hill (1)
United States (4) · Italy (3) · Spain (3) · Argentina (2) · Brazil (2) · France (2) · Greece (2) · Turkey (Türkiye) (2) · Canada (1) · China (1) · Mexico (1) · Peru (1) · Sweden (1)
Antonio Capalbo, BSc PhD (1) · Carmen Rubio, BSc PhD (1) · Carmen Rubio, PhD (1) · Doug Johnson (1) · Evangelos Papanikolaou, MD,PhD (1) · Jeannette T Bensen, Ph.D (1) · Jeff Lipton, MD (1) · Jie Qiao (1) · John Hauck (1) · Jonathan S Berg, MD, PhD (1) · Joyce Trost, PT (1) · Margaret MacMillan (1)
PMID 29067542, PMID 34127041, PMID 34798051, PMID 35896299, PMID 39059790, PMID 39315524, PMID 42074534, PMID 42850238
2019 (1), U01HG006487 (1)