79 completed, 21 unknown, 5 terminated, 4 recruiting. 37 Phase 3, 28 Not applicable, 27 Phase 2, 9 Phase 1, 7 Phase 4.
Follow Chemotherapy-induced Nausea and Vomiting: new trials by email Literature Review of Chemotherapy-induced Nausea and Vomiting trials Research Report on Chemotherapy-induced Nausea and Vomiting
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Auricular Acupressure for Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients Receiving Highly Emetogenic Chemotherapy Auricular Acupressure, Sham Auricular Acupressure - Chemotherapy-induced Nausea and Vomiting | Not applicable | Not yet recruiting | China Medical University, China | 332 | 2026-09-01 | 2026-08-12 |
| Effect of Foot Reflexology On Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients Foot Reflexology - Chemotherapy-induced Nausea and Vomiting | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 50 | 2026-06-01 | 2026-04-30 |
| The Effect of Stress Ball on Nausea, Anxiety, and Fatigue in Patients With Stomach Cancer A device/tool called a stress ball - Stomach Cancer, Chemotherapy-induced Nausea and Vomiting | Not applicable | Completed | Yuzuncu Yil University | 52 | 2026-03-20 | 2026-07-07 |
| An Exploratory Study on Efficacy and Safety of Fosaprepitant and Palonosetron Hydrochloride for Injection in Preventing CINV From Multi-Agent HEC Fosrolapitant and Palonosetron Hydrochloride for Injection, Dexamethasone, Olanzapine - Chemotherapy-induced Nausea and Vomiting | Phase 4 | Recruiting | Shanghai 6th People's Hospital | 200 | 2026-03-10 | 2026-04-30 |
| To Evaluate the Efficacy and Safety of QLM2010 for Prevention of Chemotherapy-induced Nausea and Vomiting After Highly Emetogenic Chemotherapy. QLM2010 for injection;dexamethasone, fosaprepitant dimeglumine for injection;palonosetron hydrochloride injection;dexamethasone - Chemotherapy-Induced Nausea and Vomiting | Phase 3 | Completed | Qilu Pharmaceutical Co., Ltd. | 665 | 2025-01-03 | 2025-11-18 |
| NEPA Combined With Olanzapine, Dexamethasone-sparing for the Effect of CINV in Patients Receiving HEC Regimens Netupitant / Palonosetron Oral Capsule [Akynzeo], Olanzapine, Dexamethasone Oral - Chemotherapy-induced Nausea and Vomiting, Highly Emetogenic Chemotherapy | Phase 3 | Completed | Fudan University | 644 | 2024-05-01 | 2026-04-09 |
| Effect of Guided Imagery on Chemotherapy-related Nausea and Vomiting guided imagery - Chemotherapy-induced Nausea and Vomiting, Pediatric Cancer | Not applicable | Recruiting | Baskent University | 40 | 2023-11-10 | 2026-05-01 |
| Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic Cancer Thalidomide, Nab paclitaxel, Gemcitabine - Pancreatic Cancer Stage IV, Chemotherapy-induced Nausea and Vomiting | Phase 3 | Recruiting | Fudan University | 100 | 2023-11-01 | 2023-11-24 |
| Efficacy of Ear Acupuncture in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Press needle acupuncture, Plesterin - Pediatric Cancer, Chemotherapy-induced Nausea and Vomiting | Not applicable | Completed | Universitas Indonesia | 64 | 2023-10-16 | 2024-05-23 |
| Effectiveness of Laserpuncture and Standard Antiemetic on RINVR Scores in Adolescent Patients Undergoing Chemotherapy laserpuncture, Sham Laserpuncture - Chemotherapy-induced Nausea and Vomiting | Not applicable | Completed | Universitas Indonesia | 58 | 2023-10-02 | 2024-01-29 |
| Efficacy and Safety of Intravenous Versus Oral 5-HT3 Antagonists Combined With NK-1 Receptor Antagonists for the Prevention of CINV in Breast Cancer Aprepitant, Palonosetron, Fosaprepitant - Breast Cancer, Chemotherapy-induced Nausea and Vomiting | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 1028 | 2023-07-01 | 2023-05-03 |
| Serious Gaming for Chemotherapy-induced Nausea and Vomiting eSSET-CINV - Neoplasms, Chemotherapy-induced Nausea and Vomiting | Not applicable | Recruiting | University of Central Florida | 610 | 2023-06-09 | 2026-05-01 |
| Olanzapine and 5-HT3 With or Without Dexamethasone to Prevent CINV 5HT3RA+Olanzapine, 5HT3RA+Olanzapine+Dexamethasone - Chemotherapy-induced Nausea and Vomiting | Phase 3 | Completed | Xingchen Peng | 275 | 2023-04-15 | 2025-06-04 |
| Steroid-sparing Therapy (Olanzapine) Versus Dexamethasone-based Therapy for Chemotherapy-induced Nausea and Vomiting OLA group: Olanzapine, DEX group: Dexamethasone - Chemotherapy-induced Nausea and Vomiting | Phase 4 | Terminated | The Guthrie Clinic | 23 | 2022-12-07 | 2026-09-02 |
| The Effect of Mandala Technique on Acute Nausea-vomiting and Comfort Level in Cancer Patients MANDALA TECHNIQUE - Chemotherapy-induced Nausea and Vomiting, Nursing Caries | Not applicable | Completed | Ege University | 38 | 2022-12-01 | 2024-12-02 |
| Aromatherapy for Chemotherapy-induced Nausea and Vomiting (CINV) Standard of Care Treatment for Chemotherapy Induced Nausea and Vomiting (CINV), Aromatherapy Care - Chemotherapy-induced Nausea and Vomiting | Phase 2 | Completed | University of Miami | 100 | 2022-08-01 | 2025-04-17 |
| Low Dose Olanzapine to the Prophylaxis of Nausea and Vomiting Induced by Chemotherapy in Children and Adolescents Ondansetron, Dexamethasone, Aprepitant - Chemotherapy-induced Nausea and Vomiting | Phase 3 | Unknown | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 210 | 2022-04-01 | 2022-07-28 |
| Use of Aromatherapy to Reduce Symptom Burden Essential oils, Placebo - Anxiety, Chemotherapy-induced Nausea and Vomiting | Phase 2 | Completed | Indiana University | 92 | 2022-03-07 | 2024-05-16 |
| Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC Palonosetron HCl Buccal Film 0.5 mg, IV Palonosetron 0.25 mg - Chemotherapy-induced Nausea and Vomiting | Phase 3 | Unknown | Xiamen LP Pharmaceutical Co., Ltd | 328 | 2022-03-01 | 2023-01-20 |
| The Effect of Breathing Exercise on Chemotherapy-induced Nausea and Vomiting in With Autologous Hematopoietic Stem Cell Transplantation Patients Breathing exercise group, Control group - Chemotherapy-induced Nausea and Vomiting | Not applicable | Completed | Istanbul University - Cerrahpasa | 70 | 2022-02-01 | 2024-03-06 |
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Vomiting (115) · Nausea (29) · Neoplasms (15) · Breast Neoplasms (6) · Lung Neoplasms (4) · Anxiety Disorders (2) · Colorectal Neoplasms (2) · Fatigue (2) · Gastrointestinal Neoplasms (2) · Ovarian Neoplasms (2) · Pancreatic Neoplasms (2) · Uterine Cervical Neoplasms (2) · Astrocytoma (1) · Carcinoma, Renal Cell (1) · Central Nervous System Neoplasms (1)
Pathological Conditions, Signs and Symptoms (115) · Signs and Symptoms (115) · Signs and Symptoms, Digestive (114) · Neoplasms by Site (23) · Neoplasms (22) · Urogenital Diseases (8) · Urogenital Neoplasms (8) · Digestive System Diseases (7) · Digestive System Neoplasms (7) · Neoplasms by Histologic Type (7) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Breast Diseases (6) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6)
Dexamethasone (36) · Palonosetron (24) · Aprepitant (20) · Ondansetron (17) · fosaprepitant (13) · Olanzapine (12) · Granisetron (10) · netupitant, palosentron drug combination (10) · rolapitant (6) · Calcium Dobesilate (5) · Serotonin 5-HT3 Receptor Antagonists (4) · Tropisetron (4) · netupitant (3) · Dosage Forms (2) · Dronabinol (2)
Merck Sharp & Dohme LLC (10) · Helsinn Healthcare SA (8) · Tesaro, Inc. (6) · M.D. Anderson Cancer Center (4) · Tianjin University of Traditional Chinese Medicine (3) · Beijing University of Chinese Medicine (2) · Consorzio Oncotech (2) · Fudan University (2) · GlaxoSmithKline (2) · Henan Cancer Hospital (2) · Sun Yat-sen University (2) · The Hospital for Sick Children (2) · Universitas Indonesia (2) · University of Central Florida (2) · Acacia Pharma Ltd (1)
United States (38) · China (28) · Russia (9) · Germany (8) · Canada (7) · Hungary (7) · Poland (7) · India (6) · Bulgaria (5) · Czechia (5) · Italy (5) · Ukraine (5) · Argentina (4) · Austria (4) · Croatia (4)
Dennis Vargo, MD (6) · Victoria Loerzel, PhD (2) · Alex Molasiotis, prof. (1) · Amal I. Melhem-Bertrandt, MD (1) · Anna E Efverman, PhD (1) · Antje Koller (1) · Byoungyong Shim, M.D., Ph.D. (1) · Catherine Prady, Md (1) · Christina H. Ruhlmann, MD, PhD (1) · Chuangzhen Chen (1)
PMID 19775450, PMID 22141732, PMID 26272769, PMID 28285236, PMID 30968588, PMID 11030465, PMID 12736106, PMID 15856335, PMID 17103197, PMID 18985740, PMID 19135415, PMID 19568773, PMID 19834961, PMID 20532923, PMID 20736848, PMID 20835873, PMID 22024310, PMID 23062719, PMID 23598819, PMID 24276953, PMID 24337621, PMID 24911369, PMID 25770814, PMID 25948677, PMID 26272768, PMID 26795844, PMID 26838019, PMID 26997579, PMID 27121336, PMID 27410922, PMID 27664248, PMID 27821107, PMID 28194109, PMID 28393417, PMID 28427442, PMID 28503222, PMID 28856448, PMID 29029639, PMID 29722791, PMID 30755109, PMID 30900392, PMID 31694495, PMID 32188417, PMID 32891289, PMID 32931400, PMID 33835174, PMID 34677609, PMID 35747189, PMID 35999527, PMID 36527702
2014 (1), 2018 (1), R01NR020003 (1), U10CA081920 (1)