13 completed, 5 unknown, 2 recruiting, 1 not yet recruiting. 8 Phase 4, 6 Not applicable, 4 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 5, Unknown 3 |
| Not applicable | 6 | Completed 3, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Tropisetron: new trials by email Literature Review of Tropisetron trials Research Report on Tropisetron
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial Fibrillation Local Anesthesia With Conscious Sedation, General Anesthesia, VARIPULSE Pulsed Field Ablation System - Paroxysmal Atrial Fibrillation | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 390 | 2026-06-01 | 2026-10-26 |
| Amisulpride for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Surgery Tropisetron - PONV | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 526 | 2026-05-10 | 2026-04-28 | |
| Prevention of Delayed CINV After Autologous Transplant: Olanzapine-Containing Regimen vs. Dexamethasone-Containing Regimen Fosaprepitant, Tropisetron, Olanzapine - Multiple Myeloma | Phase 3 | Recruiting | The Affiliated People's Hospital of Ningbo University | 92 | 2025-10-31 | 2026-02-17 |
| Efficacy of Three Antiemetics in Preventing Nausea and Vomiting tropisetron, metoclopramide, dexamethasone - Nausea and Vomiting | Phase 4 | Completed | The Second Affiliated Hospital of Chongqing Medical University | 200 | 2022-09-15 | 2024-04-02 |
| Effect of Glycopyrronium in Combination With Tropisetron in Anti-postoperative Nausea and Vomiting Glycopyrronium in Combination With Tropisetron, Normal Saline in Combination With Tropisetron - Postoperative Nausea and Vomiting | Phase 4 | Completed | The Second Affiliated Hospital of Chongqing Medical University | 480 | 2022-04-21 | 2024-08-16 |
| Anti-emetic Prophylaxis With or Without Dexamethasone Fosaprepitant, tropisetron, and olanzapine-based antiemetic regimen, Fosaprepitant, tropisetron, olanzapine, and dexamethasone-based antiemetic regimen - Chemotherapy-induced Nausea and Vomiting | Phase 3 | Completed | Henan Cancer Hospital | 442 | 2022-02-01 | 2024-10-10 |
| Triple Antiemetic Regimen for Chemoradiotherapy in Cervical Cancer or Nasopharyngeal Cancer Fosaprepitant, tropisetron, Dexamethasone - Cervical Cancer, Nasopharyngeal Cancer | Phase 3 | Completed | Shantou University Medical College | 116 | 2021-07-01 | 2024-02-06 |
| Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk) NEPA (300mg netupitant/0.5mg palonosetron), Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV), Dexamethasone, 8 mg (oral) or equivalent IV dose - Chemotherapy-induced Nausea and Vomiting | Phase 4 | Completed | Helsinn Healthcare SA | 414 | 2021-02-01 | 2025-12-02 |
| A Pilot Trial Evaluating the Effect of Tropisetron on Postoperative Cognitive Dysfunction After Cardiac Surgery Tropisetron, Placebos - Postoperative Cognitive Dysfunction, Postoperative Delirium | Phase 4 | Unknown | Beijing Chao Yang Hospital | 72 | 2020-11-01 | 2022-01-05 |
| The Efficacy and Safety of Tropisetron in Preventing Emergence Delirium Tropisetron, Placebos - Emergence Delirium, Postoperative Delirium | Phase 4 | Unknown | Beijing Chao Yang Hospital | 1508 | 2019-08-01 | 2020-03-11 |
| Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email - Postoperative Nausea and Vomiting | Not applicable | Completed | Vanderbilt University | 27034 | 2016-07-01 | 2019-03-07 |
| A Study Evaluating the Efficacy and Safety of Aprepitant in Autologous Hematopoietic Stem Cell Transplantation Tropisetron, Dexamethasone, Aprepitant - Vomiting | Phase 4 | Unknown | Jun Zhu | 130 | 2015-10-01 | 2016-12-30 |
| Comparative Effect Study Between Distal-proximal Point Association and Local Distribution Point Association in Chemotherapy-induced Nausea and Vomiting only antiemetic (Ramosetron, Tropisetron and dexamethasone), Matching points ST36+CV12 plus antiemetic drug, Matching points PC6+CV12 plus antiemetic drug - Chemotherapy-induced Nausea and Vomiting | Not applicable | Unknown | Tianjin University of Traditional Chinese Medicine | 240 | 2015-06-01 | 2015-06-23 |
| Transcutaneous Electrical Acupoint Stimulation of P6 to Prevent Postoperation Nausea and Vomiting Transcutaneous electrical acupoint stimulation, Sham transcutaneous electrical acupoint stimulation, Tropisetron - Postoperative Nausea and Vomiting | Not applicable | Completed | Huashan Hospital | 157 | 2014-01-01 | 2015-10-12 |
| Acupoint Electric Stimulation Combined With Tropisetron in Preventing and Treating Nausea and Vomiting After TACE acupoint electric stimulation, tropisetron - Nausea, Vomiting | Phase 2 | Unknown | Fudan University | 74 | 2013-06-01 | 2013-07-10 |
| A Korean Study of Efficacy and Safety of Aprepitant-based Triple Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in the First Cycle of Moderately Emetogenic Chemotherapy (Non-doxorubicin Hydrochloride [Adriamycin] and Cyclophosphamide Regimens) (MK-0869-225) (KMEC) Aprepitant, Aprepitant Placebo, Ondansetron - Nausea, Vomiting | Phase 4 | Completed | Merck Sharp & Dohme LLC | 494 | 2012-12-12 | 2018-09-25 |
| Emesis Control Study in Non-Hodgkin Lymphoma Patients Receiving R-CHOP Standard anti-emetics in conjunction with R-CHOP - Lymphoma, Non-Hodgkin | Not applicable | Withdrawn | Australasian Leukaemia and Lymphoma Group | 2012-01-01 | 2024-08-07 | |
| The Central Analgesic Effects of Paracetamol on Serotonergic Pathways Paracetamol, Tropisetron, Placebo - Analgesia | Not applicable | Completed | University Hospital, Basel, Switzerland | 16 | 2009-11-01 | 2013-01-29 |
| Modulation of Central Hypersensitivity in Chronic Musculoskeletal Pain by Intravenous Tropisetron Tropisetron 2 mg, Tropisetron 5mg, Placebo - Pain, Chronic Disease | Phase 2 | Completed | Insel Gruppe AG, University Hospital Bern | 30 | 2009-03-01 | 2011-03-24 |
| Clinical Confirmation of a Pharmacodynamic Interaction Between Tropisetron and Paracetamol Tropisetron, paracetamol - Pain | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 40 | 2008-06-01 | 2010-03-29 |
Showing 20 of 22. Sign in to see all of them.
Vomiting (10) · Nausea (6) · Postoperative Nausea and Vomiting (4) · Emergence Delirium (2) · Lymphoma (2) · Pain (2) · Agnosia (1) · Atrial Fibrillation (1) · Chronic Disease (1) · Hematologic Neoplasms (1) · Hyperalgesia (1) · Liver Neoplasms (1) · Lymphoma, Non-Hodgkin (1) · Multiple Myeloma (1) · Nasopharyngeal Neoplasms (1)
Beijing Chao Yang Hospital (2) · The Second Affiliated Hospital of Chongqing Medical University (2) · Australasian Leukaemia and Lymphoma Group (1) · Baylor College of Medicine (1) · China National Center for Cardiovascular Diseases (1) · Fudan University (1) · Gary Morrow (1) · Helsinn Healthcare SA (1) · Henan Cancer Hospital (1) · Huashan Hospital (1) · Insel Gruppe AG, University Hospital Bern (1) · Jun Zhu (1) · Merck Sharp & Dohme LLC (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Shantou University Medical College (1)
China (13) · Switzerland (3) · United States (3) · Czechia (1) · France (1) · Germany (1) · Greece (1) · Spain (1) · United Kingdom (1)
Alex Molasiotis, prof. (1) · Andrew Grigg, Professor (1) · Chuangzhen Chen (1) · Gary R. Morrow, PhD, MS (1) · Guangyou Duan, MD (1) · He Huang, MD (1) · Jonathan P Wanderer, MD, MPhil (1) · Jun Zhang, MD, PhD (1) · Jun Zhu, MD (1) · Ligang Ding (1) · Michele Curatolo, Prof (1) · Peipei Ye (1) · Pickering Gisele, MCU-PH (1) · Thomas Kosten, MD (1)
PMID 12906958, PMID 22952075, PMID 26507494, PMID 27821107, PMID 27826874, PMID 28069044, PMID 33052400, PMID 33790560, PMID 37402747, PMID 37851143, PMID 40859968
U01MH079639 (1)