Breast Cancer: Clinical Trials

4445 completed, 1364 unknown, 1162 recruiting, 711 terminated. 2853 Not applicable, 2186 Phase 2, 1044 Phase 1, 858 Phase 3, 176 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	2853	Completed 1436, Recruiting 419, Unknown 404, Active not recruiting 191, Not yet recruiting 155, Terminated 142, Withdrawn 84, Enrolling by invitation 13, Suspended 9
Phase 2	2186	Completed 1002, Terminated 317, Unknown 306, Recruiting 247, Active not recruiting 134, Withdrawn 90, Not yet recruiting 85, Suspended 4, Enrolling by invitation 1
Phase 1	1044	Completed 527, Terminated 141, Recruiting 117, Unknown 94, Active not recruiting 74, Withdrawn 57, Not yet recruiting 28, Suspended 5, Enrolling by invitation 1
Phase 3	858	Completed 460, Unknown 129, Recruiting 88, Active not recruiting 63, Terminated 63, Not yet recruiting 31, Withdrawn 21, Suspended 2, Enrolling by invitation 1
Phase 4	176	Completed 86, Unknown 37, Recruiting 21, Not yet recruiting 14, Terminated 9, Withdrawn 5, Active not recruiting 4
Early Phase 1	128	Completed 69, Recruiting 17, Unknown 13, Withdrawn 12, Terminated 11, Not yet recruiting 4, Enrolling by invitation 2

Follow Breast Cancer: new trials by email Literature Review of Breast Cancer trials Research Report on Breast Cancer

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Application of Multimodal MRI-based Radiomics in Histological Grading and Prognostic Assessment of Breast Cancer DCE-MRI - Breast Cancer, Breast Cancer With Low to Intermediate HER2 Expression		Not yet recruiting	Hao Xu	400	2028-01-01	2026-02-05
Gut Microbiome Changes During Abemaciclib Therapy in Breast Cancer Resistant Potato Starch, Placebo control - Breast Cancer, HER-2 Positive Breast Cancer	Not applicable	Not yet recruiting	University of Vermont Medical Center	12	2027-10-01	2026-02-12
Developing and Testing the Efficacy of AI-Chatbot-Based AIAI-Chatbot CalmMindRecoveryJourney delivering BMS-MC therapy - Breast Cancer	Not applicable	Not yet recruiting	National Taiwan University Hospital	68	2027-08-01	2026-08-27
EmpowerHer: Hybrid Digital Intervention for Breast Cancer Survivors EmpowerHer Hybrid Program - Breast Cancer, Cancer Survivors	Not applicable	Not yet recruiting	University of Valencia	147	2027-07-01	2026-06-30
Multi-4SCAR-T Therapy Targeting Breast Cancer 4SCAR T cells - Breast Cancer	Phase 1 / Phase 2	Not yet recruiting	Shenzhen Geno-Immune Medical Institute	100	2027-06-01	2026-08-26
Early Intervention Juzo Compression Sleeve and Glove, Compression Sleeve Sensor - Breast Cancer, Breast Cancer Treatment Related Lymphedema	Not applicable	Not yet recruiting	Massachusetts General Hospital	40	2027-05-01	2026-07-13
Role of Artificial Intelligence in Breast Cancer Screening Via Mammography Transpara software - Breast Cancer	Not applicable	Not yet recruiting	Centre Antoine Lacassagne	1222	2027-01-31	2026-10-20
Assessment of Biosignature Classification of DCIS for RadioTherapy Benefit Post Lumpectomy (ABCD RT) Radiation Therapy, Standard of Care Radiation Therapy, No Intervention - Breast Cancer	Phase 3	Not yet recruiting	NRG Oncology	5270	2027-01-30	2026-09-30
Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits Sobriety Digital Intervention - Breast Cancer, Alcohol Drinking	Not applicable	Not yet recruiting	University of Miami	36	2027-01-04	2026-10-20
Remotely Supervised Exercise During Chemotherapy in Women With Breast Cancer Intervention Group - Breast Cancer	Not applicable	Not yet recruiting	Riga Stradins University	60	2027-01-01	2026-07-21
Strategies to Decentralize Breast Ultrasound in Rwanda Teleultrasound with Philips Lumify ultrasound probes and Reacts software, Asynchronous virtual feedback - Breast Cancer, Early Detection of Cancer	Not applicable	Not yet recruiting	Brigham and Women's Hospital	1792	2027-01-01	2026-06-02
Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases Trastuzumab Deruxtecan, Stereotactic Radiosurgery - Breast Cancer, HER2-positive Breast Cancer	Phase 1	Not yet recruiting	Baptist Health South Florida	20	2027-01-01	2026-10-01
SOLIS: Single-Dose Radiotherapy With Omission of Lumpectomy for Intact Small Breast Cancers Stereotactic Radiation Therapy, Endocrine Therapy - Breast Cancer, Early-Stage Breast Carcinoma	Not applicable	Not yet recruiting	Renaissance Institute of Precision Oncology and Radiosurgery	30	2027-01-01	2026-09-28
Screening and the Future of Enhanced MRI for Early Breast Cancer Detection Breast MRI Screening, Questionnaires - Breast Cancer Detection, Breast Cancer	Not applicable	Not yet recruiting	Radboud University Medical Center	2628	2027-01-01	2026-10-16
ctDNA-Guided Intraventricular Therapy for CNS Malignancies CSF ctDNA-Guided Clinical Management - Leptomeningeal Disease, Glioblastoma	Not applicable	Not yet recruiting	Alireza Mansouri	77	2027-01-01	2026-07-08
Feasibility and Effectiveness of Sentinel Lymph Node Biopsy in Inflammatory Breast Cancer Sentinel node biopsy with blue dye and radioisotope - Breast Cancer	Not applicable	Not yet recruiting	Case Comprehensive Cancer Center	20	2027-01-01	2026-10-21
Wearable Device Tracked Recovery From Autologous Breast Reconstructive Surgery Questionnaires - Breast Cancer	Not applicable	Not yet recruiting	M.D. Anderson Cancer Center	50	2026-12-31	2026-09-18
Evaluation of the Safety and Efficacy of Single-Port Robot-Assisted Endoscopic Breast-Conserving Surgery and Nipple-sparing Matectomy With Reconstruction in Early-Stage Breast Cancer Patients single-port robot-assisted surgery - Breast Cancer	Not applicable	Not yet recruiting	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	30	2026-12-30	2026-08-24
Premedication With Dexamethasone for Preventing Interstitial Lung Disease in Patients With Breast Cancer Treated With Trastuzumab Deruxtecan Dexamethasone, antiemetic premedication, T-DXd - Breast Cancer, Interstitial Lung Disease (ILD)	Phase 3	Not yet recruiting	Mario Negri Institute for Pharmacological Research	244	2026-12-20	2026-10-19
ORASIS in Breast Reconstruction Use of ORASIS Device - DIEP Flap, Breast Reconstruction	Not applicable	Not yet recruiting	Duke University	30	2026-12-01	2026-07-01

Showing 20 of 8967. Sign in to see all of them.

Narrower conditions

Breast Neoplasms (8967)  ·  Neoplasms (409)  ·  Lung Neoplasms (395)  ·  Ovarian Neoplasms (386)  ·  Prostatic Neoplasms (361)  ·  Colorectal Neoplasms (346)  ·  Neoplasm Metastasis (260)  ·  Triple Negative Breast Neoplasms (216)  ·  Carcinoma, Non-Small-Cell Lung (213)  ·  Motor Activity (210)  ·  Pancreatic Neoplasms (207)  ·  Colonic Neoplasms (201)  ·  Melanoma (175)  ·  Head and Neck Neoplasms (173)  ·  Breast Neoplasms, Male (167)

Broader conditions

Skin and Connective Tissue Diseases (8967)  ·  Skin Diseases (8962)  ·  Neoplasms by Site (8959)  ·  Breast Diseases (8919)  ·  Neoplasms (8558)  ·  Pathological Conditions, Signs and Symptoms (1165)  ·  Urogenital Diseases (814)  ·  Urogenital Neoplasms (760)  ·  Genital Diseases (742)  ·  Neoplasms by Histologic Type (730)  ·  Pathologic Processes (708)  ·  Digestive System Diseases (686)  ·  Digestive System Neoplasms (672)  ·  Gastrointestinal Diseases (623)  ·  Female Urogenital Diseases and Pregnancy Complications (598)

Interventions

Cyclophosphamide (427)  ·  Trastuzumab (394)  ·  Docetaxel (361)  ·  Paclitaxel (345)  ·  Letrozole (235)  ·  Capecitabine (234)  ·  Doxorubicin (226)  ·  Tamoxifen (189)  ·  Carboplatin (183)  ·  Radiotherapy (165)  ·  Epirubicin (162)  ·  Anastrozole (158)  ·  Fulvestrant (157)  ·  Bevacizumab (125)  ·  Surveys and Questionnaires (116)

Sponsors

Memorial Sloan Kettering Cancer Center (213)  ·  Fudan University (155)  ·  M.D. Anderson Cancer Center (142)  ·  Hoffmann-La Roche (135)  ·  Dana-Farber Cancer Institute (118)  ·  AstraZeneca (115)  ·  National Cancer Institute (NCI) (109)  ·  Mayo Clinic (76)  ·  Alliance for Clinical Trials in Oncology (73)  ·  Novartis Pharmaceuticals (72)  ·  UNC Lineberger Comprehensive Cancer Center (67)  ·  Case Comprehensive Cancer Center (57)  ·  Stanford University (56)  ·  Massachusetts General Hospital (52)  ·  Pfizer (51)

Countries

United States (3817)  ·  China (1013)  ·  France (707)  ·  Canada (549)  ·  Italy (502)  ·  Spain (457)  ·  United Kingdom (440)  ·  Germany (335)  ·  South Korea (303)  ·  Belgium (292)  ·  Netherlands (244)  ·  Turkey (Türkiye) (233)  ·  Australia (214)  ·  Brazil (191)  ·  Taiwan (183)

Top investigators

Norman Wolmark, MD (30)  ·  Edith A. Perez, MD (18)  ·  Biyun Wang, Professor (15)  ·  Dimitris Mavrudis, MD (15)  ·  James N. Ingle, MD (14)  ·  Dawn Hershman, MD (13)  ·  Mothaffar Rimawi, MD (13)  ·  Carol J Fabian, MD (11)

Results publications

PMID 38979716, PMID 34037241, PMID 29522361, PMID 22508812, PMID 39606939, PMID 40207789, PMID 40443562, PMID 18355913, PMID 22649152, PMID 25071111, PMID 26348120, PMID 26438146, PMID 27432417, PMID 28898379, PMID 41170811, PMID 15894097, PMID 21796368, PMID 21880792, PMID 22198468, PMID 23871490, PMID 25439688, PMID 26101239, PMID 30207593, PMID 30711522, PMID 32101663, PMID 32580883, PMID 32840419, PMID 33326894, PMID 33736679, PMID 33853037, PMID 33856137, PMID 35594464, PMID 37302395, PMID 37338729, PMID 38153568, PMID 38335467, PMID 38598571, PMID 40421669, PMID 12165639, PMID 12393820, PMID 12473512, PMID 15172146, PMID 16157940, PMID 16360786, PMID 16546506, PMID 16598749, PMID 16758122, PMID 16783576, PMID 17236771, PMID 17273752

NIH funding

2023 (37), 2008 (32), P30CA043703 (27), 2005 (26), 2014 (26), 2025 (26), P30CA033572 (24), 2016 (23), U10CA032102 (23), 2015 (22), 2017 (21), 2019 (21), 2018 (20), P30CA068485 (19), 2009 (18)