5 completed. 5 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 5 |
| Phase 2 | 1 | Completed 1 |
Follow Brain Edema: new trials by email Literature Review of Brain Edema trials Research Report on Brain Edema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| "The Effect of Trimetazidine on the Clinical Outcome of Acute Ischemic Stroke Patients" Trimetazidine - Acute Ischemic Stroke | Phase 3 | Completed | Ain Shams University | 60 | 2024-09-01 | 2025-09-08 |
| Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism Glibenclamide, Placebo - Acute Stroke | Phase 2 / Phase 3 | Completed | Nanfang Hospital, Southern Medical University | 306 | 2018-01-01 | 2023-06-12 |
| Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis 0.45% saline replacement fluid, 0.9% saline replacement fluid, 0.45% saline intravenous fluid - Cerebral Edema, Diabetic Ketoacidosis | Phase 3 | Completed | University of California, Davis | 1389 | 2010-11-01 | 2018-06-25 |
| An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies hCRF [XERECEPT (corticorelin acetate injection)] - Brain Edema, Brain Tumor | Phase 3 | Completed | Celtic Pharma Development Services | 112 | 2005-07-01 | 2012-08-31 |
| XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors hCRF, placebo hCRF - Brain Edema, Brain Tumor | Phase 3 | Completed | Celtic Pharma Development Services | 200 | 2004-05-01 | 2014-08-13 |
Astrocytoma (2) · Brain Neoplasms (2) · Edema (2) · Ischemic Stroke (2) · Diabetic Ketoacidosis (1) · Stroke (1)
Brain Diseases (5) · Central Nervous System Diseases (5) · Nervous System Diseases (5) · Cardiovascular Diseases (2) · Central Nervous System Neoplasms (2) · Cerebrovascular Disorders (2) · Glioma (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms by Site (2) · Neoplasms, Germ Cell and Embryonal (2) · Neoplasms, Glandular and Epithelial (2) · Neoplasms, Nerve Tissue (2) · Neoplasms, Neuroepithelial (2) · Nervous System Neoplasms (2)
Corticotropin-Releasing Hormone (2) · Glyburide (1) · Trimetazidine (1)
Celtic Pharma Development Services (2) · Ain Shams University (1) · Nanfang Hospital, Southern Medical University (1) · University of California, Davis (1)
United States (3) · Canada (2) · China (1) · Egypt (1)
William Shapiro, MD (2) · Nathan Kuppermann, MD, MPH (1) · Nicole S Glaser, MD (1) · Suyue Pan, M.D., Ph.D. (1)
PMID 23382470, PMID 32527232, PMID 37965431
U01HD062417 (1)