9 completed, 3 recruiting, 2 active not recruiting, 2 terminated. 5 Not applicable, 3 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Active not recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Withdrawn 1 |
| Phase 3 | 2 | Terminated 2 |
| Phase 1 | 1 | Completed 1 |
Follow Bone Neoplasm: new trials by email Literature Review of Bone Neoplasm trials Research Report on Bone Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root Involvement Intraoperative Nerve Monitoring, Surgical Procedure, Survey Administration - Bone Neoplasm, Metastatic Malignant Neoplasm in the Bone | Not applicable | Recruiting | City of Hope Medical Center | 50 | 2027-01-10 | 2026-11-10 |
| Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor. Bone Neoplasm, Rehabilitation | Completed | Istituto Ortopedico Rizzoli | 100 | 2024-04-10 | 2026-02-03 | |
| Safety and Efficacy of Non-Setting Paste in Bone Defect Reconstruction Non-setting paste - Bone Diseases, Bone Cysts | Not applicable | Completed | Biovico Sp. z o.o. | 29 | 2023-02-28 | 2026-01-30 |
| Early Recovery After "Wedge Resection" Surgery to Remove Lung Mestastasis Secondary to Bone Cancer. assessment of the early recovery after wedge resection surgery - Metastasis Lung, Bone Neoplasm | Completed | Istituto Ortopedico Rizzoli | 75 | 2022-01-08 | 2025-02-18 | |
| Multicentric Bone Tumor Imaging Report and Data System Radiographs - Bone Neoplasm | Completed | Central Hospital, Nancy, France | 1100 | 2021-05-01 | 2026-06-17 | |
| Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery Coronavirus Infection, Orthopedic Disorder | Completed | Istituto Ortopedico Rizzoli | 40 | 2020-07-18 | 2023-05-31 | |
| Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II MR imaging - Soft Tissue Neoplasm, Bone Neoplasm | Recruiting | Central Hospital, Nancy, France | 740 | 2020-06-01 | 2020-07-21 | |
| Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases External beam radiotherapy, MR-HIFU - Bone Metastases, Bone Neoplasm | Not applicable | Active not recruiting | UMC Utrecht | 216 | 2020-03-10 | 2026-03-05 |
| Cross Cultural Validation of the Italian Version of the Bt-DUX Quality of Life, Bone Neoplasm | Completed | Istituto Ortopedico Rizzoli | 51 | 2019-08-20 | 2021-05-12 | |
| Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis combined radiotherapy and MR-HIFU - Bone Metastases, Bone Neoplasm | Phase 1 / Phase 2 | Completed | UMC Utrecht | 10 | 2019-04-11 | 2024-02-07 |
| 9-ING-41 in Patients With Advanced Cancers 9-ING-41, Gemcitabine - 21 day cycle, Doxorubicin. - Cancer, Pancreatic Cancer | Phase 2 | Active not recruiting | Actuate Therapeutics Inc. | 350 | 2019-01-04 | 2026-04-03 |
| Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas Toronto Extremity Salvage Score, Musculoskeletal Tumor Society Score, Timed Get Up and Go Test - Bone Sarcoma, Osteosarcoma | Recruiting | Memorial Sloan Kettering Cancer Center | 300 | 2018-02-14 | 2026-04-17 | |
| Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery near-infrared light nasal endoscope used with ICG - Skull Base Neoplasms, Skull Neoplasms | Not applicable | Completed | Ohio State University | 23 | 2017-11-06 | 2021-04-26 |
| MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases Thermal ablation of bone metastasis with MR-HIFU device Philips Sonalleve coupled with Philips Ingenia 3.0T, Varian Truebeam Radiotherapy System - Bone Metastases, Bone Neoplasm | Not applicable | Unknown | Turku University Hospital | 30 | 2017-05-15 | 2017-04-24 |
| Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle allograft arthrodesis of ankle - Bone Neoplasm | Unknown | Patricia Bonilla | 20 | 2014-05-20 | 2019-02-21 | |
| Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute Bioactive glass, Beta-tricalcium phosphate (ChronOs), Autograft - Bone Neoplasm | Completed | Turku University Hospital | 120 | 2009-03-01 | 2021-03-16 | |
| A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease. ibandronate [Bondronat] - Pain, Bone Neoplasm | Phase 2 | Withdrawn | Hoffmann-La Roche | 2007-06-01 | 2017-08-16 | |
| A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain ibandronate [Bondronat], zoledronic acid - Pain, Bone Neoplasm | Phase 3 | Terminated | Hoffmann-La Roche | 96 | 2005-08-01 | 2017-08-16 |
| A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease ibandronate [Bondronat], zoledronic acid - Pain, Bone Neoplasm | Phase 3 | Terminated | Hoffmann-La Roche | 163 | 2005-07-01 | 2017-08-16 |
Bone Neoplasms (19) · Neoplasm Metastasis (6) · Neoplasms (5) · Pain (5) · Bone Diseases (2) · Musculoskeletal Diseases (2) · Bone Cysts (1) · Breast Neoplasms (1) · COVID-19 (1) · Chondrosarcoma (1) · Colorectal Neoplasms (1) · Coronavirus Infections (1) · Enchondromatosis (1) · Fractures, Bone (1) · Glioma (1)
Neoplasms by Site (19) · Bone Diseases (17) · Musculoskeletal Diseases (17) · Neoplasms (14) · Neoplastic Processes (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Lung Diseases (2) · Neoplasms by Histologic Type (2) · Neoplasms, Connective and Soft Tissue (2) · Respiratory Tract Diseases (2) · Wounds and Injuries (2) · Bone Diseases, Developmental (1)
Ibandronic Acid (3) · Zoledronic Acid (2) · 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-(1,3)dioxolo(4,5-f)indol-7-yl)-pyrrole-2,5-dione (1) · Albumin-Bound Paclitaxel (1) · Carboplatin (1) · Diagnostic Imaging (1) · Doxorubicin (1) · Gemcitabine (1) · Intraoperative Neurophysiological Monitoring (1) · Irinotecan (1) · Lomustine (1) · Magnetic Resonance Imaging (1) · Paclitaxel (1) · Range of Motion, Articular (1) · Surgical Procedures, Operative (1)
Istituto Ortopedico Rizzoli (4) · Hoffmann-La Roche (3) · Central Hospital, Nancy, France (2) · Turku University Hospital (2) · UMC Utrecht (2) · Actuate Therapeutics Inc. (1) · Biovico Sp. z o.o. (1) · City of Hope Medical Center (1) · Memorial Sloan Kettering Cancer Center (1) · Ohio State University (1) · Patricia Bonilla (1)
Italy (7) · United States (6) · France (4) · Germany (3) · Netherlands (3) · Panama (3) · Poland (3) · Argentina (2) · Australia (2) · Belgium (2) · Canada (2) · Chile (2) · Finland (2) · Greece (2) · Guatemala (2)
Alana M Munger (1) · Cristiana Forni (1) · Daniel Prevedello, MD (1) · Daniel Prince, MD (1) · Gaber Komar, PhD, MD (1) · Hannu T Aro, MD, PhD (1) · Heikki Minn, Professor, MD (1) · Helena M Verkooijen, MD, PhD (1) · Mira Huhtala, MD, PhD student (1) · Stefano Bonarelli, MD (1) · Teija O Sainio, MSc, PhD Student (1)
PMID 24327518, PMID 27424289, PMID 28053024, PMID 28672195, PMID 29383130, PMID 29846250, PMID 30405781, PMID 30975030, PMID 31101621, PMID 31401903, PMID 31533931, PMID 31831767, PMID 31882719, PMID 31894292, PMID 35815408, PMID 36582001, PMID 40261174, PMID 41593389, PMID 41981308
P30CA033572 (1)