46 completed, 14 recruiting, 13 unknown, 5 terminated. 34 Not applicable, 24 Phase 2, 9 Phase 1, 8 Phase 3, 3 Phase 4.
Follow Bone Cysts: new trials by email Literature Review of Bone Cysts trials Research Report on Bone Cysts
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Osteogenic Potential of Topical Metformin Gel on Cystic Jaw Defects For the Experimental Arm: 1% Metformin Gel, For the Comparator / Control Arm: Placebo Gel - Jaw Cysts, Metformin | Not applicable | Not yet recruiting | Fayoum University | 32 | 2026-10-30 | 2026-10-14 |
| Eggshell-Derived Hydroxyapatite With Platelet-Rich Fibrin for Bone Regeneration After Jaw Cyst Removal Eggshell-Derived Hydroxyapatite With Platelet-Rich Fibrin Grafting, Eggshell-Derived Hydroxyapatite Grafting Alone - Jaw Cysts, Alveolar Bone Defects | Not applicable | Recruiting | Ahmed Nasser Ali Mabkhout | 30 | 2026-09-14 | 2026-11-12 |
| Low-Intensity Pulsed Ultrasound as an Adjunctive Therapy for Bone Regeneration Following Jaw Cyst Enucleation Low-Intensity Pulsed Ultrasound - Jaw Cysts, Curettage | Phase 3 | Not yet recruiting | Sadam Elayah | 29 | 2025-10-22 | 2025-10-07 |
| Detection of Disease Marker Factors in Cyst Fluid cyst fluid examination - Biomarkers | Recruiting | Harran University | 25 | 2025-08-25 | 2025-09-12 | |
| Bone Reconstruction With Autologous Bone Marrow Mesenchymal Stem Cells in Vitro to Repair Long Tubular Bone Defects tissue-engineered bone - Defective Composite Restorations, Bone Cysts | Not applicable | Recruiting | The First Affiliated Hospital of Xinxiang Medical College | 30 | 2025-08-07 | 2026-01-02 |
| Bone Regeneration Using PRF After Cyst Enucleation Autologous Platelet-Rich Fibrin (PRF), Conventional Surgical Management - Odontogenic Cyst, Jaw Cysts | Not applicable | Recruiting | Sana'a University | 20 | 2025-05-19 | 2026-02-20 |
| Clinical and Radiographic Characteristics and Outcomes of Guided Apicoectomy With Retrograde Mineral Trioxide Aggregate Filling for Periapical Cysts Guided Apicoectomy With Retrograde Mineral Trioxide Aggregate Filling - Periapical Cyst | Not applicable | Completed | Can Tho University of Medicine and Pharmacy | 42 | 2025-05-03 | 2026-07-24 |
| Role of Platelet Rich Plasma in Bone Regeneration After Enucleation of Odontogenic Jaw Cysts PRP & bone regeneration - PRP & Jaw Cysts | Not applicable | Not yet recruiting | Assiut University | 42 | 2024-12-01 | 2024-12-06 |
| Patient Specific Implants (PSIs) for the Decompression of Odontogenic Cysts Preoperative Cone Beam Computed Tomography (CBCT) scan, Cystostomy, Histology to confirm the initial diagnosis - Odontogenic Cysts, Odontogenic Keratocyst | Recruiting | Semmelweis University | 20 | 2024-11-26 | 2026-04-24 | |
| Using of Bone Marrow Stem Cell Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Reconstruction of Upper Jaw Bony Cystic Defects, Comparing with Platelet Rich Fibrin with Bone Graft Bone marrow stem cells concentrate , platelet rich fibrin , bone graft, platelet rich fibrin and bone graft - Maxillary Cyst | Phase 3 | Not yet recruiting | Cairo University | 22 | 2024-10-26 | 2024-10-29 |
| Treatment of Mandibular Bone Cyst by Navigation and Endoscopy Navigation and endoscopy - Jaw Cysts | Not applicable | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 122 | 2024-08-20 | 2024-08-22 |
| Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery PBM treatment, PBM sham treatment, EMS - Apical Periodontitis, Endodontically Treated Teeth | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 90 | 2024-08-20 | 2026-08-17 |
| Effect of Targeted Endodontic Microsurgery on Quality of Life and Healing on Mandibular Molars Targeted Endodontic Microsurgery Using 3d Printed surgical guide using the patient's CBCT data, Conventional Endodontic Microsurgery with a free hand procedure using bur and CBCT analysis - Periapical Diseases, Periapical Periodontitis | Not applicable | Completed | Postgraduate Institute of Dental Sciences Rohtak | 62 | 2024-07-01 | 2026-09-17 |
| Examining the Effect of Different Filling Techniques on Healing in Lesional Teeth retrograde and orthograde root canal filling - Apical Cyst | Not applicable | Completed | TC Erciyes University | 60 | 2024-05-08 | 2026-09-30 |
| Bone Defects Reconstruction After Dentigerous Cyst Enucleation With Autogenous Demineralized Dentin Matrix- ADDM and Advanced Platelet-Rich Fibrin- A-PRF. Impacted third molar extraction, Advanced Platelet-Rich Fibrin (A-PRF), Mandibular dentigerous cyst enucleation - Impact Molar, Mandible Cyst | Not applicable | Active not recruiting | Jagiellonian University | 35 | 2024-04-04 | 2026-06-23 |
| Marrow Cellution™ vs. Traditional BMA Harvest Project Bone Marrow Collection - Hip Arthropathy, Avascular Necrosis of Bone | Not applicable | Recruiting | Ohio State University | 6 | 2024-03-25 | 2026-04-01 |
| Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome Patidegib Topical Gel, Patidegib Topical Gel with no active patidegib - Gorlin Syndrome | Phase 3 | Completed | Sol-Gel Technologies, Ltd. | 113 | 2024-03-17 | 2026-09-18 |
| Volumetric Changes in Large Cystic Lesions Using Active Decompression and Distraction Sugosteogenesis vs Passive Decompression Active decompression - Odontogenic Cysts | Not applicable | Unknown | Radwa Hydar Ragab | 10 | 2024-03-01 | 2024-02-16 |
| Intravenous Dexamethasone on Postoperative Pain and Complications in Jaw Surgery Dexamethasone - Tooth Extraction Status Nos, Cysts Dental | Phase 4 | Completed | Selcuk University | 60 | 2024-01-01 | 2026-06-29 |
| Reproductive Options in Inherited Skin Diseases Ichthyosis, Palmoplantar Keratoses | Enrolling by invitation | Maastricht University Medical Center | 650 | 2024-01-01 | 2025-05-18 |
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Basal Cell Nevus Syndrome (35) · Carcinoma, Basal Cell (23) · Odontogenic Cysts (16) · Jaw Cysts (11) · Radicular Cyst (11) · Bone Cysts, Aneurysmal (5) · Periapical Diseases (4) · Periapical Periodontitis (4) · Skin Neoplasms (4) · Neoplasms (3) · Periapical Granuloma (3) · Tuberous Sclerosis (3) · Xeroderma Pigmentosum (3) · Albinism (2)
Cysts (91) · Musculoskeletal Diseases (91) · Neoplasms (88) · Stomatognathic Diseases (72) · Jaw Diseases (71) · Jaw Cysts (59) · Bone Diseases (54) · Odontogenic Cysts (46) · Neoplasms by Histologic Type (37) · Bone Diseases, Developmental (36) · Abnormalities, Multiple (35) · Congenital Abnormalities (35) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (35) · Genetic Diseases, Inborn (35)
HhAntag691 (5) · sonidegib (4) · Eye Enucleation (3) · IPI-926 (3) · gusacitinib (3) · 1-phenyl-3,3-dimethyltriazene (2) · Aminolevulinic Acid (2) · Apicoectomy (2) · Cystostomy (2) · Decompression (2) · Denosumab (2) · Drug Evaluation (2) · Photochemotherapy (2) · Radionuclide Imaging (2) · tazarotene (2)
UCSF Benioff Children's Hospital Oakland (6) · Novartis Pharmaceuticals (4) · Sol-Gel Technologies, Ltd. (4) · Ascend Biopharmaceuticals Ltd (3) · Maastricht University Medical Center (3) · Semmelweis University (3) · Ain Shams University (2) · Assiut University (2) · Cairo University (2) · Fayoum University (2) · PellePharm, Inc. (2) · Tanta University (2) · The Hospital for Sick Children (2) · Ahmed Nasser Ali Mabkhout (1) · Akdeniz University (1)
United States (26) · Egypt (10) · France (8) · Canada (7) · Netherlands (7) · United Kingdom (7) · Germany (6) · Italy (6) · Belgium (5) · Turkey (Türkiye) (5) · Australia (4) · Spain (4) · Austria (3) · China (3) · Hungary (3)
Ervin Epstein, MD (5) · Antoni Gostynski, MD, PhD (2) · David R. Bickers, MD (2) · Edward V. Maytin, MD, PhD (2) · Gregory Siller (2) · Mohamed K Allam, Ass prof (2) · AJ Gelderblom, Prof (1) · Abdalla Awidi (1) · Adam Anz (1) · Ahmad Vosough, MD (1) · Alexey Y. Drobyshev, MD,PhD,Prof. (1) · Allen E. Bale, MD (1) · Andrew Howard, MD (1)
PMID 21194990, PMID 26250795, PMID 31735221, PMID 11873920, PMID 12424446, PMID 12796876, PMID 15170272, PMID 18038077, PMID 18801672, PMID 22211085, PMID 22670904, PMID 24441673, PMID 24576437, PMID 24623282, PMID 25631867, PMID 26428611, PMID 26612576, PMID 26692930, PMID 27025231, PMID 27838224, PMID 28193444, PMID 28377093, PMID 28700034, PMID 28809378, PMID 28953676, PMID 29175429, PMID 30128061, PMID 30573706, PMID 30758760, PMID 3127567, PMID 31786170, PMID 32145206, PMID 33663899, PMID 34324108, PMID 34510239, PMID 34703121, PMID 34749963, PMID 35165005, PMID 35407667, PMID 36116543, PMID 37449658, PMID 39204985, PMID 39548448, PMID 40083317, PMID 40340767, PMID 41176605
R01CA109584 (2), 2015 (1), 2023 (1), P30CA124435 (1), U10CA098543 (1), U10CA180886 (1), U19CA081888 (1)