7 completed, 2 terminated, 1 recruiting, 1 unknown. 4 Not applicable, 3 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Terminated 1, Unknown 1 |
| Phase 2 | 3 | Completed 3 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Articular Cartilage Disorder of Knee: new trials by email Literature Review of Articular Cartilage Disorder of Knee trials Research Report on Articular Cartilage Disorder of Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prednisolone Urinary Excretion Kinetics Prednisolone - Articular Cartilage Disorder of Knee | Withdrawn | University Hospital, Strasbourg, France | 2023-05-01 | 2024-03-20 | ||
| Evaluation of Treatment of Osteoarthritis of the Knee in the Form of Chondromalacia of the Articular Cartilage Treated in the Arthroscopic Technique With the Use of:Autogenous Transplantation of Fragmented Adipose Tissue,PRP GF,Mesenchymal Cells,Hyaluronic Acid-low Molecular Weight and Cross-linked Autogenous transplant of fragmented adipose tissue taken from abdominal integuments, PRP GF (platelet-rich plasma with growth factors), Mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest - Osteoarthritis, Knee, Chondral Defect | Not applicable | Completed | eMKa MED Medical Center | 150 | 2022-12-12 | 2025-08-07 |
| Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage microfracture surgery + HST003 - Articular Cartilage Disorder of Knee, Cartilage Damage | Phase 1 | Terminated | Histogen | 1 | 2021-11-15 | 2023-01-19 |
| A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea, JointRep®, Microfracture - Chondral Defect, Articular Cartilage Defect | Not applicable | Unknown | Oligo Medic Pty Ltd | 185 | 2021-09-22 | 2024-03-20 |
| The Clinical Outcome of BiCRI in the Treatment of Chondral and Osteochondral Lesions Biphasic Cartilage Repair Implant (BiCRI) - Articular Cartilage Disorder of Knee | Not applicable | Completed | BioGend Therapeutics Co.Ltd | 11 | 2019-05-20 | 2025-09-25 |
| Radiofrequency-Based Debridement vs. Mechanical Debridement for the Treatment of Articular Cartilage Lesions Radiofrequency-Based Debridement, Mechanical Debridement - Articular Cartilage Disorder of Knee | Not applicable | Terminated | Christopher Kaeding | 6 | 2018-11-08 | 2021-09-30 |
| A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee MACI, microfracture - Chondral Defect, Osteochondritis Dissecans (OCD) | Phase 3 | Recruiting | Vericel Corporation | 45 | 2018-10-24 | 2026-10-13 |
| Efficacy and Safety Study of Intra-Articular Injections of Autologous Peripheral Blood Stem Cells Following Subchondral Drilling Surgery for the Treatment of Articular Cartilage Injury in the Knee Autologous peripheral blood stem cells and hyaluronic acid, Hyaluronic acid - Articular Cartilage Disorder of Knee, Articular Cartilage; Degeneration | Phase 2 | Completed | KLSMC Stem Cells, Inc. | 120 | 2015-12-01 | 2022-08-16 |
| Mesenchymal Stem Cells in Knee Cartilage Injuries Autologous Mesenchymal Stem Cells - Articular Cartilage Disorder of Knee, Osteoarthritis, Knee | Phase 2 | Completed | University of Jordan | 13 | 2014-01-01 | 2016-02-24 |
| the Safety and Efficacy Evaluation of Chondron Compared With Mircrofracture of Knee Defect of Articular Cartilage, Articular Cartilage Disorder of Knee | Completed | Cellontech Co., Ltd. | 21 | 2012-01-01 | 2026-04-07 | |
| Effect of Autologous Peripheral Blood Stem Cell Treatment on Articular Cartilage Regeneration Peripheral blood stem cells and hyaluronic acid injections, Hyaluronic Acid - Articular Cartilage Disorder of Knee | Phase 2 | Completed | Kuala Lumpur Sports Medicine Centre | 50 | 2009-10-01 | 2015-03-17 |
| Serum Cartilage Oligomeric Matrix Protein Levels After 12 Weeks of Different Exercises Running exercise, Cycling exercise, Swimming Exercise - Osteoarthritis, Articular Cartilage Disorder of Knee | Early Phase 1 | Completed | Middle East Technical University | 48 | 2008-01-01 | 2015-06-10 |
Fractures, Stress (3) · Osteoarthritis, Knee (2) · Cartilage Diseases (1) · Osteoarthritis (1) · Osteochondritis Dissecans (1) · Tooth, Impacted (1)
Musculoskeletal Diseases (4) · Arthritis (3) · Fractures, Bone (3) · Joint Diseases (3) · Rheumatic Diseases (3) · Wounds and Injuries (3) · Osteoarthritis (2) · Bone Diseases (1) · Connective Tissue Diseases (1) · Osteochondritis (1) · Skin and Connective Tissue Diseases (1) · Stomatognathic Diseases (1) · Tooth Diseases (1)
Arthroplasty, Subchondral (2) · Hyaluronic Acid (2) · Intercellular Signaling Peptides and Proteins (1) · Prednisolone (1)
BioGend Therapeutics Co.Ltd (1) · Cellontech Co., Ltd. (1) · Christopher Kaeding (1) · Histogen (1) · KLSMC Stem Cells, Inc. (1) · Kuala Lumpur Sports Medicine Centre (1) · Middle East Technical University (1) · Oligo Medic Pty Ltd (1) · University Hospital, Strasbourg, France (1) · University of Jordan (1) · Vericel Corporation (1) · eMKa MED Medical Center (1)
United States (4) · Malaysia (2) · Australia (1) · Canada (1) · France (1) · Jordan (1) · Poland (1) · South Korea (1) · Taiwan (1) · Turkey (Türkiye) (1)
Abdallah Awidi, MD (1) · Bruce Caldwell, MBBS, FRACS (1) · Christopher Kaeding, M.D. (1) · Feza Korkusuz, PhD (1) · Gwen Chang (1) · Hiba Khalil, PhD (1) · Jonathan Hopper, BSc (Hons), MB ChB, FRCSEd (1) · Khay-Yong Saw, Dr. (1) · Mahasen S Najjar, MD (1) · Mark A Hubka (1) · Myung Goo Kim, MD (1) · Ozgur Celik, PhD (1)