2 not yet recruiting, 1 completed. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Not yet recruiting 2, Completed 1 |
Follow Aortic Valve, Calcification of: new trials by email Literature Review of Aortic Valve, Calcification of trials Research Report on Aortic Valve, Calcification of
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Pioglitazone in Calcific Aortic Valve Disease Drug: Pioglitazone Oral Tablet, Placebo - Calcification of Aortic Valve, Aortic Valve Stenosis | Phase 2 | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 100 | 2023-07-01 | 2023-05-25 |
| Folic Acid Supplementation in Calcific Aortic Valve Disease Folic Acid Oral Tablet, Placebo - Calcification of Aortic Valve, Aortic Valve Stenosis | Phase 2 | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 100 | 2023-07-01 | 2023-05-17 |
| Study Investigating the Effect of Drugs Used to Treat Osteoporosis on the Progression of Calcific Aortic Stenosis. Denosumab, Alendronic Acid, Denosumab Placebo - Calcific Aortic Stenosis | Phase 2 | Completed | University of Edinburgh | 152 | 2014-11-12 | 2021-10-14 |
Aortic Valve Stenosis (3) · Osteoporosis (1)
Aortic Valve Disease (3) · Cardiovascular Diseases (3) · Heart Diseases (3) · Heart Valve Diseases (3) · Ventricular Outflow Obstruction (3) · Bone Diseases (1) · Bone Diseases, Metabolic (1) · Metabolic Diseases (1) · Musculoskeletal Diseases (1) · Nutritional and Metabolic Diseases (1)
Alendronate (1) · Denosumab (1) · Folic Acid (1) · Pioglitazone (1)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · University of Edinburgh (1)
United Kingdom (1)
David E Newby, BA BSc PhD BM DM FRCP DSc FRSE (1) · Rong Bing, MbChB (1)
PMID 25882205, PMID 26227196, PMID 27733431, PMID 29555836, PMID 33913339, PMID 39248270, PMID 40050004, PMID 41473954