3 recruiting, 2 completed, 1 unknown, 1 withdrawn. 3 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Recruiting 2, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Antibiotic Allergy: new trials by email Literature Review of Antibiotic Allergy trials Research Report on Antibiotic Allergy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing, Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge, Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge - Drug Allergy, Cephalosporin Allergy | Phase 2 | Recruiting | Massachusetts General Hospital | 300 | 2025-05-05 | 2026-09-04 |
| Support Tool for Antibiotic Allergy deLabeling EPR search - Antibiotic Allergy | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 3000 | 2025-03-10 | 2025-12-16 |
| Repertoire and Properties of Anti-drug Antibodies Involved in Immediate Hypersensitivity in the Operating Room IgG group, IgE group, IgG group + IgE group - Hypersensitivity, Immediate, Peri-operative Injury | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 40 | 2023-04-12 | 2024-09-19 |
| Penicillin Allergy Risk-Stratification and Delabeling of Low-Risk Patients Physician-targeted CDS tool for PCN allergy delabeling - Antibiotic Allergy | Not applicable | Withdrawn | Vanderbilt University Medical Center | 2022-12-01 | 2024-03-08 | |
| Topical Antibiotic Prophylaxis for Eyelids Topical Antibiotic Product, Topical Non-Antibiotic Ointment - Antibiotic Side Effect, Eyelid; Wound | Phase 4 | Completed | University of California, San Francisco | 401 | 2017-10-02 | 2020-07-21 |
| Improved Basophil Activation Test (BAT) in the Diagnostics of Drug Allergy Drug Allergy, Antibiotic Allergy | Unknown | The Republican Research and Practical Center for Epidemiology and Microbiology | 45 | 2017-01-03 | 2018-12-17 | |
| Drug Challenges Without Prior Skin Testing Placebo-Controlled Graded Drug Challenge - Drug Hypersensitivity, Penicillin Allergy | Phase 1 | Completed | Montefiore Medical Center | 166 | 2016-01-13 | 2021-11-16 |
Drug Hypersensitivity (4) · Hypersensitivity (3) · Anaphylaxis (2) · Epilepsy, Idiopathic Generalized (1) · Eyelid Diseases (1) · Hypersensitivity, Immediate (1) · Surgical Wound (1) · Surgical Wound Infection (1) · Wounds and Injuries (1)
Chemically-Induced Disorders (4) · Drug-Related Side Effects and Adverse Reactions (4) · Immune System Diseases (3) · Eye Diseases (1) · Hypersensitivity, Immediate (1) · Infections (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Postoperative Complications (1) · Wound Infection (1)
Ampicillin (1) · Bacitracin (1) · Cefaclor (1) · Cefadroxil (1) · Cefazolin (1) · Cefdinir (1) · Cefepime (1) · Cefixime (1) · Cefotaxime (1) · Cefpodoxime (1) · Ceftazidime (1) · Ceftriaxone (1) · Cefuroxime (1) · Cephalexin (1) · Erythromycin (1)
Assistance Publique - Hôpitaux de Paris (1) · Massachusetts General Hospital (1) · Montefiore Medical Center (1) · The Republican Research and Practical Center for Epidemiology and Microbiology (1) · Universitaire Ziekenhuizen KU Leuven (1) · University of California, San Francisco (1) · Vanderbilt University Medical Center (1)
United States (4) · Belarus (1) · Belgium (1) · France (1)
Andrei Hancharou, Dr (1) · Aurelie Gouel, MD, PhD (1) · David A Khan, MD (1) · Elina Jerschow, MD, MSc (1) · Iryna U Ramanava (1) · James Antoon, MD, PhD (1) · Kimberly G Blumenthal, MD, MSc (1) · Rik Schrijvers, MD, PhD (1) · Robert Kersten, MD (1)
U01AI184071 (1)