12 completed, 4 recruiting, 2 active not recruiting, 2 unknown. 22 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 22 | Completed 12, Recruiting 4, Active not recruiting 2, Unknown 2, Not yet recruiting 1, Withdrawn 1 |
Follow Ankyloglossia: new trials by email Literature Review of Ankyloglossia trials Research Report on Ankyloglossia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectivity of P1821, a Novel Tongue Strengthening and Endurance Enhancing Speech Flow Exercise P1821 - Ankyloglossia, Impairment of Speech | Not applicable | Recruiting | Dream Video LLC | 100 | 2026-11-01 | 2026-11-04 |
| SNIP follow-on Case Series Using v3 Device Frenectomy of anterior ankylogossia using the novel device - Ankyloglossia | Not applicable | Not yet recruiting | Europa Life Sciences Limited | 6 | 2026-10-01 | 2026-09-04 |
| Case Series of Infants With Anterior Ankyloglossia Being Treated by the Sublingual Neonatal Incision Platform Device Frenectomy of anterior ankylogossia using the novel device - Ankyloglossia | Not applicable | Active not recruiting | Europa Life Sciences Limited | 6 | 2026-03-10 | 2026-06-18 |
| The Impact of Post-Frenotomy Massages on Ankyloglossia Recurrence and Feeding Outcomes Post-frenotomy massage - Ankyloglossia | Not applicable | Recruiting | Isaac Elijah | 150 | 2025-01-27 | 2026-08-03 |
| Post-Procedural Manual Manipulation for Infant Ankyloglossia Post-frenotomy manual manipulation - Ankyloglossia, Breastfeeding Support | Not applicable | Recruiting | Georgetown University | 110 | 2024-10-15 | 2025-02-17 |
| Healing Efficacy of Diode Laser in Lingual Frenectomy Lingual Frenectomy using 940nm Diode Laser, Lingual Frenectomy using High-frequency Electrosurgery - Ankyloglossia, Tongue-tie | Not applicable | Recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 53 | 2024-10-01 | 2026-04-30 |
| Frenuloplasty for Speech and Myofunctional Outcomes Lingual frenuloplasty - Ankyloglossia, Speech Delay | Not applicable | Unknown | The Oregon Clinic | 50 | 2024-07-01 | 2024-04-03 |
| Breastfeeding Duration and Tongue-tie in Neonates. Frenotomy - Infant Nutrition Disorders | Not applicable | Completed | Hvidovre University Hospital | 100 | 2023-11-17 | 2025-09-19 |
| Use of Inhaled Colostrum to Control Pain in Neonatal Frenotomy and Comparison to Inhaled Lavender Essential Oil Colostrum - Pain, Ankyloglossia | Not applicable | Completed | Parc de Salut Mar | 142 | 2023-09-18 | 2025-03-11 |
| Physiotherapy in the Treatment of Breastfeeding Difficulties Myofunctional therapy - Breastfeeding, Ankyloglossia | Not applicable | Completed | Universidad de Almeria | 200 | 2023-07-01 | 2024-07-31 |
| Lingual Frenulum in Newborn Infants (LINNE) Frenotomy, Oral physiotherapy - Tongue Tie, Frenulum Breve | Not applicable | Active not recruiting | University of Oulu | 300 | 2022-10-03 | 2026-01-08 |
| The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day Surgeries ibuprofen suppository - Ankyloglossia, Oral Mucoceles | Not applicable | Completed | The Children's Hospital of Zhejiang University School of Medicine | 120 | 2022-09-01 | 2023-05-26 |
| Dedicated Lactation Support in Infants With Tongue - Tie; a Randomised Control Trial phrenectomy, Increased lactation support - Ankyloglossia, Breast Feeding, Exclusive | Not applicable | Withdrawn | Princess Anna Mazowiecka Hospital, Warsaw, Poland | 2022-03-08 | 2022-07-21 | |
| The Use of Lavender vs Vanilla Essential Oil as Complementary Analgesia for Frenotomy in Healthy Newborns Case (use of inhaled vanilla essential oil), Control (use of inhaled lavender essential oil) - Ankyloglossia | Not applicable | Unknown | Parc de Salut Mar | 142 | 2021-05-10 | 2021-04-30 |
| Analgesia in Lingual Frenulotomy in the Newborn Sugar and water solution, Sterile water - Frenulum Breve | Not applicable | Completed | IRCCS Burlo Garofolo | 72 | 2020-09-18 | 2025-05-07 |
| Analgesic Effect of Inhaled Lavender Essential Oil for Clipping of Tongue-ties Lavender essential oil - Ankyloglossia | Not applicable | Completed | Parc de Salut Mar | 142 | 2020-08-18 | 2022-01-28 |
| The Impact of Lingual Frenotomy on Bottle Feeding Mechanics Lingual frenotomy - Ankyloglossia, Feeding, Bottle | Not applicable | Completed | The Oregon Clinic | 47 | 2019-08-01 | 2021-09-14 |
| Prospective Evaluation of Lingual Frenotomy in Newborns With Simultaneous Lip Tie for the Relief of Breastfeeding Pain. Lingual Frenotomy, Labial Frenotomy, Sham Procedure - Ankyloglossia, Breast Feeding | Not applicable | Completed | University of South Florida | 120 | 2015-05-01 | 2019-06-12 |
| Breastfeeding Improvement Following Tongue-tie and Lip-tie Release Lingual Frenotomy and/or maxillary labial frenectomy - Ankyloglossia, Breastfeeding | Not applicable | Completed | The Oregon Clinic | 237 | 2014-06-01 | 2015-12-30 |
| Anterior Lingual Frenectomy is Inadequate in Improving Breastfeeding Outcomes: a Prospective Cohort Study Lingual frenotomy and/or maxillary labial frenectomy - Ankyloglossia, Breastfeeding | Not applicable | Completed | The Oregon Clinic | 55 | 2014-06-01 | 2017-09-20 |
Showing 20 of 22. Sign in to see all of them.
Breast Feeding (9) · Pain (3) · Pain, Postoperative (2) · Bottle Feeding (1) · Dentofacial Deformities (1) · Hyperthermia (1) · Infant Nutrition Disorders (1) · Lactation Disorders (1) · Language Development Disorders (1) · Motor Activity (1) · Tooth, Supernumerary (1) · lip tie (1)
Stomatognathic Diseases (22) · Behavior (10) · Feeding Behavior (10) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Pain (2) · Pathologic Processes (2) · Postoperative Complications (2) · Stomatognathic System Abnormalities (2) · Body Temperature Changes (1) · Breast Diseases (1) · Communication Disorders (1)
Oral Frenectomy (2) · Therapeutics (2) · Lasers, Semiconductor (1) · Myofunctional Therapy (1) · Physical Therapy Modalities (1) · Sugars (1) · lavender oil (1)
The Oregon Clinic (4) · Parc de Salut Mar (3) · Europa Life Sciences Limited (2) · Dream Video LLC (1) · Georgetown University (1) · Hvidovre University Hospital (1) · IRCCS Burlo Garofolo (1) · Isaac Elijah (1) · Princess Anna Mazowiecka Hospital, Warsaw, Poland (1) · The Children's Hospital of Zhejiang University School of Medicine (1) · United States Naval Medical Center, Portsmouth (1) · Universidad de Almeria (1) · University of Medicine and Pharmacy at Ho Chi Minh City (1) · University of Oulu (1) · University of South Florida (1)
United States (6) · Spain (3) · United Kingdom (2) · China (1) · Denmark (1) · Finland (1) · Italy (1) · Poland (1) · South Korea (1) · Vietnam (1)
Aung Soe (1) · Aung Soe, MBChB MSc FRCPCH AFHEA (1) · Bobak A Ghaheri, MD (1) · Bobak Ghaheri, MD (1) · Chiara Navarra, DDS MSc PhD (1) · Diana Skaaning (1) · Earl H Harley, MD (1) · Fangqi Gong, doctor (1) · Maddalena Chermetz, DDS MSc (1) · Milena Cadenaro, DDS MSc PhD (1) · Outi Aikio, MD, PhD (1) · Pat Ricalde, MD (1)
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2023 (1)