9 recruiting, 6 completed, 2 not yet recruiting, 2 terminated. 10 Not applicable, 3 Phase 2, 3 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Androgen Deprivation Therapy: new trials by email Literature Review of Androgen Deprivation Therapy trials Research Report on Androgen Deprivation Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autonomic and Renal Contributions to Hypertension With ADT Gonadotropin Releasing Hormone Agonists (GNRH), Androgen receptor (AR) inhibitor, Placebo - Androgen Deprivation Therapy, Prostate Cancer | Phase 4 | Recruiting | Virginia Commonwealth University | 50 | 2026-08-01 | 2026-09-30 |
| Effects of Combined Training in Prostate Cancer Patients Combined training - Prostate Cancer Patients, Androgen Deprivation Therapy | Not applicable | Not yet recruiting | Universidade Federal de Santa Catarina | 46 | 2026-06-15 | 2026-07-02 |
| Radiotherapy After Prostatectomy for Node Positive Prostate Cancer Androgen Deprivation Therapy (ADT), radiotherapy - Prostate Cancer (Post Prostatectomy), Radiotherapy; Image-Guided | Phase 3 | Recruiting | Sun Yat-sen University | 372 | 2026-03-20 | 2026-06-16 |
| Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy fezolinetant - reference formulation, Placebo - Prostate Cancer, Prostate Cancer (Adenocarcinoma) | Phase 2 | Recruiting | Shehzad Basaria, M.D. | 60 | 2026-01-14 | 2026-08-17 |
| Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture Acupuncture, Lifestyle Management - Hot Flashes, Acupuncture Therapy | Not applicable | Recruiting | Inova Health Care Services | 24 | 2026-01-08 | 2026-02-04 |
| Fezolinetant for Treating Hot Flashes in Men With Prostate Cancer Fezolinetant - Prostate CA, Androgen Deprivation Therapy | Phase 2 | Recruiting | University of Vermont | 32 | 2025-12-18 | 2026-02-05 |
| Identifying Fundamental Mechanisms of Skeletal Muscle Ageing in Older Men Undergoing Androgen Deprivation Therapy: a Feasibility Study Sarcopenia, Prostate Cancer | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 20 | 2025-09-01 | 2025-08-21 | |
| Impact of Multimodal Telerehabilitation in Rural Patients With Metastatic Prostate Cancer Telerehabilitation Intervention - Prostate Cancer, Metastatic Prostate Cancer | Not applicable | Recruiting | University of Utah | 74 | 2025-05-27 | 2025-08-01 |
| Relugolix + Enzalutamide Study in High-Risk Prostate Cancer Relugolix and Enzalutamide - Androgen Deprivation Therapy, Locally Advanced Prostate Cancer | Phase 1 | Recruiting | University of Oklahoma | 46 | 2024-12-26 | 2026-03-05 |
| Contributions to Hypertension With Androgen Deprivation Therapy Gonadotropin Releasing Hormone Agonists (GNRH), Androgen receptor (AR) inhibitor, Placebo - Androgen Deprivation Therapy, Prostate Cancer | Phase 4 | Terminated | University of Colorado, Denver | 10 | 2023-09-20 | 2026-09-02 |
| Short Versus Long-term Androgen Deprivation Therapy With Salvage Radiotherapy in Prostate Cancer. URONCOR 0624 triptorelin, goserelin, leuprorelin - Prostate Cancer, Salvage Radiotherapy | Phase 3 | Recruiting | Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic | 534 | 2023-03-14 | 2023-11-18 |
| EvaluatioN of HIFU Hemiablation and Short Term AndrogeN Deprivation Therapy Combination to Enhance Prostate Cancer Control. HIFU hemi-ablation combined with ADT. - Prostate Cancer, Androgen Deprivation Therapy | Phase 2 | Completed | Institut Mutualiste Montsouris | 19 | 2023-03-07 | 2026-10-02 |
| Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy Aerobic and resistance exercise, Usual Care - Androgen Deprivation Therapy, Prostate Cancer | Not applicable | Recruiting | Dana-Farber Cancer Institute | 62 | 2022-08-11 | 2026-07-29 |
| Feasibility and Safety of Physical Exercise in Men With Prostate Cancer PE Intervention - Prostate Cancer, Androgen Deprivation Therapy | Not applicable | Completed | Azienda USL Reggio Emilia - IRCCS | 5 | 2020-04-14 | 2022-10-19 |
| RegisterPROS - A Registry for Prostate Cancers PROSTest - Prostate Cancer (Adenocarcinoma), Prostate Biopsy | Enrolling by invitation | Wren Laboratories LLC | 1000 | 2020-01-15 | 2026-08-21 | |
| Walking Football as a Supportive Medicine for Patients With Prostate Cancer Walking football training - Prostate Cancer, Androgen Deprivation Therapy | Not applicable | Unknown | Associacao de Investigacao de Cuidados de Suporte em Oncologia | 50 | 2019-07-11 | 2020-01-13 |
| Intramuscular Mechanisms of Androgen Deprivation-related Sarcopenia GnRH agonist - Metastatic Prostate Cancer, Androgen Deprivation Therapy | Completed | Seattle Institute for Biomedical and Clinical Research | 60 | 2018-12-07 | 2024-09-04 | |
| Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose Zoladex - Prostate Cancer, Resistance Exercise | Not applicable | Terminated | Norwegian School of Sport Sciences | 23 | 2018-09-21 | 2023-03-27 |
| Home-based Exercise Intervention for Patients With Metastatic Prostate Cancer Home-based exercise - Castration-resistant Prostate Cancer, Androgen Deprivation Therapy | Not applicable | Completed | UNC Lineberger Comprehensive Cancer Center | 22 | 2017-04-01 | 2021-04-20 |
| Supervised Group Based Exercise for Men With Prostate Cancer on Androgen Deprivation Therapy Group based exercise - Prostatic Neoplasms, Exercise Therapy | Not applicable | Completed | Herlev Hospital | 200 | 2014-08-01 | 2019-08-30 |
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Prostatic Neoplasms (20) · Motor Activity (5) · Hot Flashes (3) · Adenocarcinoma (2) · Hypertension (2) · Kidney Diseases (2) · Primary Dysautonomias (2) · Sarcopenia (2) · Multiple Endocrine Neoplasia Type 1 (1) · Muscular Atrophy (1) · Neoplasm, Residual (1) · Osteoporosis (1) · Pathologic Complete Response (1)
Neoplasms (21) · Genital Diseases (20) · Genital Diseases, Male (20) · Genital Neoplasms, Male (20) · Male Urogenital Diseases (20) · Neoplasms by Site (20) · Prostatic Diseases (20) · Urogenital Diseases (20) · Urogenital Neoplasms (20) · Pathological Conditions, Signs and Symptoms (6) · Behavior (5) · Signs and Symptoms (5) · Nervous System Diseases (4) · Atrophy (2) · Autonomic Nervous System Diseases (2)
Goserelin (4) · Androgen Antagonists (3) · Leuprolide (3) · Flutamide (2) · Receptors, Androgen (2) · bicalutamide (2) · enzalutamide (2) · Absorptiometry, Photon (1) · Acupuncture Therapy (1) · Blood Specimen Collection (1) · Exercise (1) · Gonadotropin-Releasing Hormone (1) · Radiotherapy (1) · Triptorelin Pamoate (1) · fezolinetant (1)
Associacao de Investigacao de Cuidados de Suporte em Oncologia (1) · Azienda USL Reggio Emilia - IRCCS (1) · Dana-Farber Cancer Institute (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Herlev Hospital (1) · Inova Health Care Services (1) · Institut Mutualiste Montsouris (1) · Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic (1) · Norwegian School of Sport Sciences (1) · Odense University Hospital (1) · Seattle Institute for Biomedical and Clinical Research (1) · Shehzad Basaria, M.D. (1) · Sun Yat-sen University (1) · UNC Lineberger Comprehensive Cancer Center (1) · Universidade Federal de Santa Catarina (1)
United States (10) · Denmark (3) · China (1) · France (1) · Germany (1) · Italy (1) · Norway (1) · Portugal (1) · Spain (1)
Matthew Babcock, PhD (2) · Abdel Halim, PhD, PharmD (1) · Andreia Capela, MD (1) · Bo Abrahamsen, MD, PhD, Professor (1) · Christina C Dieli-Conwright, PhD, MPH (1) · Claus Dahl, MD (1) · Erik D Hanson, PhD (1) · Jeanny Aragon-Ching, MD (1) · Jose M Garcia, MD, PhD (1) · Kambiz Rahbar, MD (1) · Kim Brixen, MD, PhD, Professor (1) · Liru He, PhD (1) · Mads H Poulsen, MD (1) · Manish Kohli, MD (1)
PMID 20559064, PMID 24330570, PMID 24344218, PMID 24944128, PMID 24944134, PMID 24944135, PMID 26572756, PMID 26620651, PMID 26632144, PMID 27357198, PMID 28263373, PMID 29514170, PMID 35292485, PMID 37025594, PMID 39041411, PMID 40451460, PMID 40640763, PMID 42031503
K01HL164978 (1)