12 completed, 1 recruiting. 13 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 13 | Completed 12, Recruiting 1 |
| Phase 2 | 4 | Completed 3, Recruiting 1 |
Follow Altitude Sickness: new trials by email Literature Review of Altitude Sickness trials Research Report on Altitude Sickness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Advair HFA in Healthy and HAPE Predisposed Subjects Advair HFA, Placebo - Altitude Edema | Phase 1 / Phase 2 | Recruiting | University of Colorado, Denver | 60 | 2023-12-12 | 2025-09-22 |
| Sickness Evaluation at Altitude With Acetazolamide at Relative Doses Acetazolamide Pill - Acute Mountain Sickness | Phase 1 | Completed | Stanford University | 108 | 2019-08-09 | 2019-10-22 |
| Spectroscopic and Diffusion Weighted Analysis of the Effects of Dexamethasone on High Altitude Cerebral Oedema (HACE) Dexamethasone, Placebo - High Altitude Cerebral Edema | Phase 1 | Completed | University Hospitals Coventry and Warwickshire NHS Trust | 10 | 2019-01-14 | 2024-06-18 |
| Sickness Evaluation at Altitude With Acetazolamide at Relative Dosages Acetazolamide - Acute Mountain Sickness | Phase 1 | Completed | Stanford University | 105 | 2018-08-04 | 2018-11-20 |
| Altitude Sickness Prevention With Ibuprofen Relative to Acetazolamide and Treatment Efficacy Ibuprofen, Acetazolamide - Acute Mountain Sickness | Phase 1 | Completed | Grant S Lipman | 92 | 2017-08-12 | 2018-11-26 |
| Study of Compound Danshen Dripping Pills to Treat Acute Mountain Sickness Placebo, Compound danshen dripping pills - Acute Mountain Sickness | Phase 1 / Phase 2 | Completed | Tasly Pharmaceuticals, Inc. | 58 | 2016-06-24 | 2017-09-01 |
| Inhaled Budesonide and Acute Mountain Sickness Budesonide 200, Budesonide 800, Placebo - Acute Mountain Sickness | Phase 1 | Completed | Salzburger Landeskliniken | 51 | 2016-06-01 | 2016-10-14 |
| Effects of Non-steroidal Anti-inflammatory Drugs (NSAIDS) on Acclimatization to High Altitude Ibuprofen, Sugar pill - High Altitude | Phase 1 | Completed | University of California, San Francisco | 20 | 2014-09-01 | 2021-04-06 |
| A Study to Test the Safety of Combined Dosing With Aminophylline and Ambrisentan in Exercising Healthy Human Volunteers at Simulated High Altitude Aminophylline 400 mg, Ambrisentan 5 mg, Placebo - Acute Mountain Sickness and Fatigue | Phase 1 | Completed | Robert J Noveck, M.D. | 92 | 2013-09-01 | 2015-11-13 |
| Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru N-acetylcysteine, Acetazolamide, Placebo pills - Erythrocytosis, Mountain Sickness | Phase 1 / Phase 2 | Completed | University of Colorado, Denver | 85 | 2013-06-01 | 2015-05-15 |
| Safety Evaluation of Aminophylline and Methazolamide Aminophylline, Methazolamide, Aminophylline and Methazolamide - Mountain Sickness | Phase 1 | Completed | Poudre Valley Health System | 16 | 2011-12-01 | 2017-02-10 |
| Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia Bosentan, Bosentam TRACLEER - Hypoxia-Induced Pulmonary Artery Hypertension | Phase 1 | Completed | Assistance Publique - Hôpitaux de Paris | 20 | 2006-01-01 | 2008-10-17 |
| Prevention of High Altitude Pulmonary Edema dexamethasone 8 mg bid, tadalafil 10mg bid - High Altitude Pulmonary Edema | Phase 1 / Phase 2 | Completed | University of Zurich | 30 | 2003-07-01 | 2006-12-04 |
Hypoxia (3) · Fatigue (1) · Polycythemia (1)
Respiration Disorders (13) · Respiratory Tract Diseases (13) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Signs and Symptoms, Respiratory (3) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1)
Acetazolamide (4) · Aminophylline (2) · Dexamethasone (2) · Ibuprofen (2) · Acetylcysteine (1) · BID protein, human (1) · Bosentan (1) · Ethylenediamines (1) · Fluticasone (1) · Fluticasone-Salmeterol Drug Combination (1) · Gels (1) · Methazolamide (1) · Salmeterol Xinafoate (1) · Sugars (1) · Tadalafil (1)
Stanford University (2) · University of Colorado, Denver (2) · Assistance Publique - Hôpitaux de Paris (1) · Grant S Lipman (1) · Poudre Valley Health System (1) · Robert J Noveck, M.D. (1) · Salzburger Landeskliniken (1) · Tasly Pharmaceuticals, Inc. (1) · University Hospitals Coventry and Warwickshire NHS Trust (1) · University of California, San Francisco (1) · University of Zurich (1)
United States (7) · Austria (1) · China (1) · France (1) · Peru (1) · United Kingdom (1)
Abdias Hurtado, MD (1) · Carrie Jurkiewicz, MD (1) · Christopher Imray, PhD MBBS (1) · Claude A Piantadosi, MD (1) · Gary Luckasen, M.D. (1) · James P Maloney, MD (1) · John Feiner, MD (1) · Marc M Berger, MD (1) · Marco Maggiorini, MD (1) · Min Zhao, PhD (1) · Philip Bickler, PhD/MD (1) · Richard Fuquay, MD (1) · Richard Johnson, MD (1) · Robert J Noveck, MD, PhD (1)
PMID 10732898, PMID 17015867, PMID 22829927, PMID 28890439, PMID 30419226, PMID 31651350, PMID 32479750