14 active not recruiting. 14 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Active not recruiting 14 |
| Phase 1 | 3 | Active not recruiting 3 |
Follow Advanced Cancer: new trials by email Literature Review of Advanced Cancer trials Research Report on Advanced Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psilocybin in Cancer Pain Study Psilocybin - Opioid-Related Disorders, Pain Management | Phase 2 | Active not recruiting | Yvan Beaussant, MD, MSci | 15 | 2024-09-23 | 2026-10-27 |
| Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer Psilocybin - Advanced Cancer, Stage IV Solid Tumor Cancer | Phase 2 | Active not recruiting | University Health Network, Toronto | 15 | 2024-06-06 | 2026-06-22 |
| Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21) Adagrasib - Advanced Cancer, Metastatic Cancer | Phase 2 | Active not recruiting | Mirati Therapeutics Inc. | 200 | 2024-02-01 | 2026-08-14 |
| A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors TST001, Oxaliplatin, Capecitabine - Advanced Cancer | Phase 1 / Phase 2 | Active not recruiting | Transcenta Therapeutics (Hangzhou) Co., Ltd. | 320 | 2020-08-13 | 2026-09-29 |
| A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors TST001, Nivolumab Injection [Opdivo], mFOLFOX6 - Advanced Cancer, Gastric Cancer | Phase 1 / Phase 2 | Active not recruiting | Transcenta Therapeutics (Hangzhou) Co., Ltd. | 150 | 2020-05-28 | 2026-09-29 |
| Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) Osimertinib, Ramucirumab - Non Small Cell Lung Cancer, EGFR Gene Mutation | Phase 2 | Active not recruiting | Xiuning Le | 160 | 2019-07-25 | 2026-04-17 |
| TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation No Further Treatment, TSR-042 - Cervical Cancer, Advanced Cancer | Phase 2 | Active not recruiting | Grupo Español de Investigación en Cáncer de Ovario | 134 | 2019-06-28 | 2026-06-17 |
| Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1 MRTX849, Pembrolizumab, Cetuximab - Advanced Cancer, Metastatic Cancer | Phase 1 / Phase 2 | Active not recruiting | Mirati Therapeutics Inc. | 731 | 2019-01-15 | 2026-07-29 |
| A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy Avelumab, Best Supportive Care - Penile Cancer, Advanced Cancer | Phase 2 | Active not recruiting | University Health Network, Toronto | 25 | 2018-08-15 | 2026-07-06 |
| Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer Pembrolizumab, DPX-Survivac, Cyclophosphamide - Advanced Cancer, Ovarian Cancer | Phase 2 | Active not recruiting | University Health Network, Toronto | 47 | 2018-02-12 | 2025-09-19 |
| A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer Ramucirumab, Merestinib, Cisplatin - Biliary Tract Cancer, Metastatic Cancer | Phase 2 | Active not recruiting | Eli Lilly and Company | 309 | 2016-05-19 | 2026-07-22 |
| Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) pembrolizumab - Advanced Cancer, Anal Carcinoma | Phase 2 | Active not recruiting | Merck Sharp & Dohme LLC | 1609 | 2015-12-18 | 2025-09-22 |
| Intrapleural Catheter Daily Versus Three Times a Week Drainage Intrapleural catheter (IPC) drained, IPC Placement, Chest X-Ray - Advanced Cancer, Pleural Effusion | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 257 | 2008-08-22 | 2026-10-13 |
| Effects of Mirtazapine on Appetite in Advanced Cancer Patients Mirtazapine, Placebo - Advanced Cancer, Anorexia | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 98 | 2007-01-08 | 2026-06-12 |
Neoplasm Metastasis (5) · Biliary Tract Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Colorectal Neoplasms (2) · Pancreatic Neoplasms (2) · Uterine Cervical Neoplasms (2) · Agnosia (1) · Anorexia (1) · Anus Neoplasms (1) · Bile Duct Neoplasms (1) · Carcinoid Tumor (1) · Cholangiocarcinoma (1) · Colonic Neoplasms (1) · Endocrine Gland Neoplasms (1) · Endometrial Neoplasms (1)
Neoplasms by Site (11) · Neoplasms (10) · Pathological Conditions, Signs and Symptoms (8) · Pathologic Processes (6) · Endocrine System Diseases (5) · Neoplastic Processes (5) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Endocrine Gland Neoplasms (4) · Genital Diseases (4) · Respiratory Tract Diseases (4) · Respiratory Tract Neoplasms (4) · Thoracic Neoplasms (4) · Urogenital Diseases (4) · Urogenital Neoplasms (4)
Gemcitabine (3) · pembrolizumab (3) · Cisplatin (2) · Nivolumab (2) · Psilocybin (2) · Ramucirumab (2) · adagrasib (2) · Afatinib (1) · Albumin-Bound Paclitaxel (1) · Capecitabine (1) · Cetuximab (1) · Cyclophosphamide (1) · Mirtazapine (1) · Oxaliplatin (1) · Paclitaxel (1)
University Health Network, Toronto (3) · M.D. Anderson Cancer Center (2) · Mirati Therapeutics Inc. (2) · Transcenta Therapeutics (Hangzhou) Co., Ltd. (2) · Eli Lilly and Company (1) · Grupo Español de Investigación en Cáncer de Ovario (1) · Merck Sharp & Dohme LLC (1) · Xiuning Le (1) · Yvan Beaussant, MD, MSci (1)
United States (8) · Canada (3) · Spain (3) · Turkey (Türkiye) (3) · France (2) · Mexico (2) · South Korea (2) · Taiwan (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · China (1) · Croatia (1)
Amit Oza, M.D. (1) · Ana Oaknin, PhD (1) · Carlos A. Jimenez, MD (1) · Charlie Qi, MD (1) · Sarah Hales, MD (1) · Shalini Dalal, MD (1) · Srikala Sridhar, M.D. (1) · Xiuning Le, MD PhD (1) · Yvan Beaussant, MD (1)
PMID 30943124, PMID 31682550, PMID 31980466, PMID 32359091, PMID 32919526, PMID 33836153, PMID 34161704, PMID 34592180, PMID 34990208, PMID 35114169, PMID 35167329, PMID 35361487, PMID 35404402, PMID 35444013, PMID 35588692, PMID 35658005, PMID 35680043, PMID 35777186, PMID 35835611, PMID 36546659, PMID 36748723, PMID 36999619, PMID 37099736, PMID 37327468, PMID 39378386, PMID 39979665, PMID 40121391, PMID 41152967, PMID 41920388, PMID 42129168
2015 (2), 2023 (2), 2018 (1)