13 completed, 6 terminated, 1 withdrawn. 9 Phase 1, 7 Phase 2, 5 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 7, Terminated 2 |
| Phase 2 | 7 | Completed 7 |
| Not applicable | 5 | Terminated 4, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Adult Oligodendroglioma: new trials by email Literature Review of Adult Oligodendroglioma trials Research Report on Adult Oligodendroglioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas Hyperfractionated radiation therapy, Stereotactic radiosurgery, Alisertib - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 17 | 2015-01-30 | 2025-04-30 |
| 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas 18F-fluoro-dihydroxyphenylalanine, Positron emission tomography (PET), Computed tomography (CT) - Adult Anaplastic Ependymoma, Adult Anaplastic Oligodendroglioma | Not applicable | Terminated | Erik Mittra | 2 | 2014-12-01 | 2017-03-20 |
| Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors gallium Ga 68-edotreotide, positron emission tomography, computed tomography - Acoustic Schwannoma, Adult Anaplastic Astrocytoma | Not applicable | Withdrawn | Sue O'Dorisio | 2013-09-01 | 2017-04-28 | |
| Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma tumor lysate-pulsed autologous dendritic cell vaccine, laboratory biomarker analysis - Adult Diffuse Astrocytoma, Adult Mixed Glioma | Phase 2 | Completed | Jonsson Comprehensive Cancer Center | 5 | 2012-01-10 | 2020-11-04 |
| Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Gadobenate Dimeglumine, Gadobutrol - Adult Anaplastic (Malignant) Meningioma, Adult Anaplastic Astrocytoma | Not applicable | Terminated | University of Southern California | 14 | 2011-12-14 | 2017-03-27 |
| Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery cognitive assessment, magnetic resonance imaging, laboratory biomarker analysis - Adult Diffuse Astrocytoma, Adult Mixed Glioma | Completed | Radiation Therapy Oncology Group | 82 | 2011-10-01 | 2015-03-18 | |
| Yoga Therapy in Treating Patients With Malignant Brain Tumors yoga therapy, questionnaire administration, quality-of-life assessment - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Not applicable | Terminated | Wake Forest University Health Sciences | 9 | 2010-12-01 | 2018-07-03 |
| Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma biopsy, computed tomography, therapeutic conventional surgery - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Early Phase 1 | Completed | Mayo Clinic | 24 | 2010-07-26 | 2025-09-02 |
| RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma 3-Dimensional Conformal Radiation Therapy, Gamma-Secretase Inhibitor RO4929097, Intensity-Modulated Radiation Therapy - Acoustic Schwannoma, Adult Anaplastic (Malignant) Meningioma | Phase 1 | Completed | National Cancer Institute (NCI) | 22 | 2010-05-01 | 2015-09-29 |
| Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma erlotinib hydrochloride, isotretinoin, laboratory biomarker analysis - Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma | Phase 1 | Terminated | Wake Forest University Health Sciences | 5 | 2010-05-01 | 2018-08-01 |
| Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma Laboratory Biomarker Analysis, Perifosine, Temsirolimus - Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 36 | 2010-01-27 | 2021-07-19 |
| Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas proton beam radiation therapy, quality-of-life assessment, questionnaire administration - Adult Brain Tumor, Adult Brain Stem Glioma | Phase 1 / Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 23 | 2009-12-17 | 2020-12-10 |
| Everolimus in Treating Patients With Recurrent Low-Grade Glioma Everolimus, Archival Tissue Analysis - Adult Diffuse Astrocytoma, Adult Mixed Glioma | Phase 2 | Completed | Susan Chang | 58 | 2009-01-23 | 2020-07-28 |
| Sunitinib in Treating Patients With Recurrent Malignant Gliomas sunitinib malate, pharmacological study - Adult Anaplastic Astrocytoma, Adult Diffuse Astrocytoma | Phase 2 | Completed | National Cancer Institute (NCI) | 31 | 2007-06-01 | 2016-02-29 |
| Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer bevacizumab, placebo, magnetic resonance imaging - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2007-06-01 | 2014-05-09 |
| Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors EF5, conventional surgery, positron emission tomography - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 46 | 2005-06-01 | 2013-01-16 |
| Imatinib Mesylate in Treating Patients With Recurrent Brain Tumor Imatinib Mesylate, Laboratory Biomarker Analysis, Pharmacological Study - Adult Anaplastic Oligodendroglioma, Adult Mixed Glioma | Phase 1 / Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 64 | 2003-06-01 | 2019-10-21 |
| Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction erlotinib hydrochloride, laboratory biomarker analysis - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 1 | Completed | National Cancer Institute (NCI) | 75 | 2001-12-01 | 2013-01-16 |
| Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma etanidazole, conventional surgery, pharmacological study - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Not applicable | Terminated | National Cancer Institute (NCI) | 48 | 2001-07-01 | 2013-01-16 |
| Stereotactic Radiosurgery in Treating Patients With Brain Tumors Sterotactic radiosurgery - Adult Central Nervous System Germ Cell Tumor, Adult Malignant Meningioma | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 1998-11-01 | 2023-10-31 |
Glioma (20) · Oligodendroglioma (20) · Astrocytoma (18) · Brain Neoplasms (14) · Ependymoma (13) · Glioblastoma (13) · Gliosarcoma (13) · Pinealoma (8) · Meningioma (7) · Choroid Plexus Neoplasms (6) · Glioma, Subependymal (6) · Medulloblastoma (6) · Neuroectodermal Tumors, Primitive (6) · Craniopharyngioma (4) · Esthesioneuroblastoma, Olfactory (2)
Neoplasms by Histologic Type (20) · Neoplasms, Germ Cell and Embryonal (20) · Neoplasms, Glandular and Epithelial (20) · Neoplasms, Nerve Tissue (20) · Neuroectodermal Tumors (20) · Neoplasms (18) · Neoplasms, Neuroepithelial (18) · Nervous System Diseases (17) · Brain Diseases (16) · Central Nervous System Diseases (16) · Neoplasms by Site (16) · Nervous System Neoplasms (16) · Central Nervous System Neoplasms (15) · Meningeal Neoplasms (7) · Neoplasms, Vascular Tissue (7)
Magnetic Resonance Spectroscopy (6) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (4) · Congresses as Topic (2) · Erlotinib Hydrochloride (2) · Surgical Procedures, Operative (2) · fluorodopa F 18 (2) · 2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1) · Bevacizumab (1) · Biopsy (1) · Etanidazole (1) · Everolimus (1) · Gadolinium DTPA (1) · Imatinib Mesylate (1) · Isotretinoin (1) · MLN 8237 (1)
National Cancer Institute (NCI) (7) · Wake Forest University Health Sciences (2) · Abramson Cancer Center at Penn Medicine (1) · Alliance for Clinical Trials in Oncology (1) · Erik Mittra (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · National Institutes of Health Clinical Center (CC) (1) · Radiation Therapy Oncology Group (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · Sue O'Dorisio (1) · Susan Chang (1) · University of Southern California (1)
United States (20) · Canada (1)
Ali Choucair (1) · Antonio Omuro (1) · Antonius Miller (1) · Brian G. Fuller (1) · Erik Mittra, MD, PhD (1) · Glenn Lesser (1) · Kevin Judy (1) · Kurt Jaeckle, MD (1) · M. Sue O'Dorisio, MD, PhD (1) · Meng Law (1) · Monica Loghin (1) · Nadia N. Laack, M.D. (1) · Robert Cavaliere (1) · Robert Lustig (1) · Robert Prins (1)
P30CA008748 (2), U01CA069856 (2), N01CM62202 (1), N01CM62203 (1), N01CM62206 (1), N01CM62207 (1), P30CA014089 (1), P30CA016058 (1), P30CA016672 (1), P30CA086862 (1), P30CA124435 (1), R21CA093007 (1), U10CA025224 (1), U10CA031946 (1), U10CA037422 (1)