107 completed, 49 unknown, 15 terminated, 13 withdrawn. 198 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 198 | Completed 107, Unknown 49, Terminated 15, Withdrawn 13, Recruiting 5, Active not recruiting 4, Not yet recruiting 4, Suspended 1 |
Follow Adnexal Diseases: new trials by email Literature Review of Adnexal Diseases trials Research Report on Adnexal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CYTALUX Dose Extension Study CYTALUX (pafolacianine) injection - Cancer in the Lung, Ovarian Cancer | Phase 4 | Not yet recruiting | On Target Laboratories, LLC | 106 | 2026-08-15 | 2026-08-18 |
| Effects of Metformin and Theory-Based Education in Women With Polycystic Ovary Syndrome MetFORMIN, Matching Placebo, Theory-Based Behavioral Educational Program - Polycystic Ovary Syndrome (PCOS) Women | Phase 4 | Completed | Jerash Private University | 900 | 2026-08-01 | 2026-09-10 |
| Study Evaluating Safety, Tolerability, and Metabolism of Niraparib Niraparib - Ovarian Cancer | Phase 4 | Recruiting | University of Miami | 70 | 2026-07-28 | 2026-08-05 |
| Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy Cyclobenzaprine - Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified | Phase 4 | Not yet recruiting | Christiana Care Health Services | 36 | 2026-07-01 | 2026-06-24 |
| A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese Tirzepatide as an adjunct to lifestyle intervention, Placebo as an adjunct to lifestyle intervention - Polycystic Ovary Syndrome (PCOS), Obesity & Overweight | Phase 4 | Recruiting | University of Bonn | 198 | 2025-12-09 | 2026-01-08 |
| Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery Indocyanine Green, Near-Infrared Fluorescence Imaging System - Gynecologic Cancers, Ovarian Cancer | Phase 4 | Not yet recruiting | Istanbul University | 50 | 2025-09-01 | 2025-03-14 |
| Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS Metformin, Matching Placebo - Polycystic Ovary Syndrome (PCOS) Women | Phase 4 | Completed | Jerash Private University | 400 | 2025-08-01 | 2026-08-31 |
| Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome Micronized progesterone 200 MG, Micronized Progesterone 100 MG - Turner Syndrome, Primary Ovarian Insufficiency (Poi) | Phase 4 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2025-07-31 | 2026-08-25 |
| Comparison of Clomiphene Alone Versus Clomiphene Plus Sildenafil for Ovulation in Women With Polycystic Ovary Syndrome Clomiphene Citrate 100 mg, Sildenafil Citrate 25Mg Tab, Placebo - Polycystic Ovarian Syndrome (PCOS), Polyendocrine Metabolic Ovarian Syndrome (PMOS) | Phase 4 | Completed | Nishtar Medical University | 98 | 2025-07-01 | 2026-08-18 |
| Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian Syndrome Myo-Inositol and D-Chiro-Inositol Combination Therapy, placebo (folic acid) - Polycystic Ovary Syndrome (PCOS), Myo-inositol | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-06-01 | 2026-07-14 |
| Liraglutide Treatment in Obese Infertile PCOS Women Liraglutide and metformin, Metformin - PCOS, Obesity | Phase 4 | Recruiting | Peking University Third Hospital | 890 | 2025-05-22 | 2025-05-29 |
| A Trial to Evaluate the Safety of Niraparib Tablets in Adult Female Participants With Advanced or Relapsed Epithelial Ovarian Cancer Niraparib - Ovarian Neoplasms | Phase 4 | Not yet recruiting | GlaxoSmithKline | 67 | 2025-04-22 | 2025-03-21 |
| OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults Olaparib, Lenvatinib, Sunitinib - Renal Cell Carcinoma, Ovarian Carcinoma | Phase 4 | Unknown | University Medical Center Groningen | 30 | 2024-05-01 | 2023-11-29 |
| Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome Canagliflozin 100mg Tab, Metformin Hydrochloride - Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease | Phase 4 | Unknown | Ping Li,MD | 50 | 2024-03-31 | 2024-02-13 |
| Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation in Women With Polycystic Ovarian Syndrome Metformin 1000 mg Oral Tablet, Dapagliflozin 10 MG Oral Tablet [Farxiga], Combined Dapagliflozin-Metformin 5/1000mg - Induction of Ovulation, PCO - Polycystic Ovaries | Phase 4 | Completed | Beni-Suef University | 500 | 2023-10-20 | 2026-10-06 |
| First Line Treatment With Olaparib in Combination With Bevacizumab in HRD Positive Patients Olaparib, Bevacizumab - Carcinoma, Ovarian Epithelial | Phase 4 | Active not recruiting | Mario Negri Institute for Pharmacological Research | 190 | 2023-09-15 | 2026-06-25 |
| Clinicalămetabolomics and the Study of Intestinal Flora of Jinfeng Pills in the Treatment of Polycystic Ovary Syndrome Jinfeng Pill - Polycystic Ovary Syndrome | Phase 4 | Unknown | Peking Union Medical College Hospital | 105 | 2023-09-01 | 2025-02-12 |
| Letrozole Versus Hormonal Preparation in Frozen Cycles of PCOS Patients. Letrozole 2.5mg - Frozen Embryo Transfer, Polycystic Ovarian Disease | Phase 4 | Withdrawn | Dubai Fertility Center | 2023-08-01 | 2024-02-20 | |
| Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan Metformin - Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance Syndrome | Phase 4 | Completed | Jerash Private University | 25 | 2023-06-01 | 2026-08-12 |
| Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS Metformin Hydrochloride - Polycystic Ovary Syndrome, Metformin | Phase 4 | Active not recruiting | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 150 | 2023-05-27 | 2026-10-07 |
Showing 20 of 198. Sign in to see all of them.
Polycystic Ovary Syndrome (120) · Infertility (37) · Ovarian Neoplasms (31) · Anovulation (18) · Ovarian Hyperstimulation Syndrome (15) · Obesity (13) · Insulin Resistance (12) · Primary Ovarian Insufficiency (10) · Breast Neoplasms (8) · Hyperandrogenism (7) · Ovarian Cysts (6) · Endometritis (5) · Pelvic Inflammatory Disease (5) · Carcinoma, Ovarian Epithelial (4) · Endometrial Neoplasms (4)
Female Urogenital Diseases (198) · Female Urogenital Diseases and Pregnancy Complications (198) · Genital Diseases (198) · Genital Diseases, Female (198) · Urogenital Diseases (198) · Endocrine System Diseases (188) · Gonadal Disorders (188) · Ovarian Diseases (188) · Neoplasms (160) · Cysts (126) · Ovarian Cysts (120) · Endocrine Gland Neoplasms (35) · Genital Neoplasms, Female (35) · Neoplasms by Site (35)
Metformin (46) · Clomiphene (20) · Letrozole (10) · Estradiol (9) · Chorionic Gonadotropin (7) · Folic Acid (7) · Menotropins (6) · Progesterone (6) · Triptorelin Pamoate (6) · Leuprolide (5) · cetrorelix (5) · Ethinyl Estradiol (4) · Gonadotropins (4) · Inositol (4) · Liraglutide (4)
University Magna Graecia (15) · Odense University Hospital (5) · University Medical Centre Ljubljana (4) · Assiut University (3) · First Affiliated Hospital, Sun Yat-Sen University (3) · Jerash Private University (3) · Mohamed Sayed Abdelhafez (3) · Shanghai 10th People's Hospital (3) · AGUNCO Obstetrics and Gynecology Centre (2) · Assaf-Harofeh Medical Center (2) · Bing He (2) · Cairo University (2) · China Academy of Chinese Medical Sciences (2) · Damascus University (2) · Eugonia (2)
United States (33) · China (24) · Italy (23) · Egypt (15) · Denmark (11) · Spain (5) · Canada (4) · France (4) · United Kingdom (4) · Austria (3) · Greece (3) · India (3) · Iran (3) · Israel (3) · Jordan (3)
Stefano Palomba, MD (14) · Francesco Orio, MD (8) · Achille Tolino, MD (7) · Fulvio Zullo, MD (3) · Mohamed S Abdelhafez, Dr (3) · Shen Qu, Dr (3) · Abdul Hakim Nattouf, MD, PhD (2) · Ahmed Gibreel, Dr (2) · Ahmed Gibreel, MD (2) · Ahmed Maged, MD (2) · Lawrence Engmann, MD (2) · Marwan Alhalabi, MD, PhD (2) · Rachel Mejia, DO (2) · Sally Kadoura, B Pharm, MD (2) · Tryfon Lainas, PhD (2)
PMID 23857221, PMID 27529295, PMID 28143456, PMID 33347618, PMID 34732660, PMID 11163814, PMID 11726570, PMID 12046553, PMID 14688154, PMID 17536071, PMID 17766923, PMID 17854523, PMID 18158291, PMID 18165618, PMID 18172212, PMID 18375410, PMID 18403419, PMID 18440534, PMID 18544618, PMID 18647805, PMID 18997670, PMID 19383827, PMID 19933994, PMID 20008886, PMID 2005218, PMID 20118030, PMID 20148739, PMID 20189560, PMID 20215625, PMID 20435692, PMID 20471009, PMID 20660041, PMID 20716255, PMID 20730705, PMID 20858697, PMID 21123449, PMID 21209881, PMID 21325466, PMID 21601197, PMID 21606131, PMID 21733508, PMID 21880799, PMID 21982727, PMID 22341881, PMID 22343553, PMID 22500852, PMID 22579050, PMID 22777527, PMID 22999793, PMID 23211475
2018 (2), K12HD001259 (1), K23HL119602 (1), K24HD001357 (1), P50HD012303 (1), R01DA013131 (1), R01HL075079 (1)