2 completed, 2 recruiting, 2 unknown, 1 withdrawn. 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 2, Recruiting 2, Unknown 2, Withdrawn 1 |
Follow Acute Stress Disorder: new trials by email Literature Review of Acute Stress Disorder trials Research Report on Acute Stress Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BXCL501 After Stress to Increase Recovery Success BXCL501 (dexmedetomidine HCl), Placebo - Acute Stress Reaction, Acute Stress Disorder | Phase 2 | Recruiting | University of North Carolina, Chapel Hill | 100 | 2026-02-23 | 2026-04-14 |
| Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room Intranasal Dexmedetomidine (4 mcg/kg), Intranasal Fentanyl (2 mcg/kg), Intranasal Midazolam (5 mg/kg) - Acute Stress Disorder, Anxiety | Phase 2 | Withdrawn | Nationwide Children's Hospital | 2025-09-01 | 2025-09-10 | |
| Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL) Cyclobenzaprine HCl, Placebo - Acute Stress Reaction, Acute Stress Disorder | Phase 2 | Recruiting | University of North Carolina, Chapel Hill | 180 | 2025-03-25 | 2026-10-22 |
| PTSD Prevention Using Oral Hydrocortisone Placebo, Hydrocortisone - PTSD, Acute Stress Disorder | Phase 2 | Completed | Rachel Yehuda | 201 | 2022-01-12 | 2026-03-19 |
| Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma Propranolol, Placebo - Trauma and Stressor Related Disorders, Post Traumatic Stress Disorder | Phase 2 | Unknown | Douglas Mental Health University Institute | 150 | 2021-08-01 | 2021-07-29 |
| Efficacy of Prazosin in Preventing Post-traumatic Stress Disorder Prazosin, ALPRESS® LP 2,5 et 5 mg - Acute Stress Disorder | Phase 2 | Completed | Hospices Civils de Lyon | 15 | 2017-04-21 | 2026-05-27 |
| Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators Propranolol Hydrochloride, Placebo - Trauma and Stressor Related Disorders, Post-traumatic Stress Disorders | Phase 2 | Unknown | Douglas Mental Health University Institute | 64 | 2017-03-30 | 2021-06-18 |
Stress Disorders, Traumatic, Acute (7) · Stress Disorders, Post-Traumatic (5) · Adjustment Disorders (2) · Trauma and Stressor Related Disorders (2) · Anxiety Disorders (1) · Pain (1) · Wounds and Injuries (1)
Mental Disorders (7) · Stress Disorders, Traumatic (7) · Trauma and Stressor Related Disorders (5) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Dexmedetomidine (2) · Propranolol (2) · Fentanyl (1) · Hydrocortisone (1) · Prazosin (1) · Sugars (1) · cyclobenzaprine (1)
Douglas Mental Health University Institute (2) · University of North Carolina, Chapel Hill (2) · Hospices Civils de Lyon (1) · Nationwide Children's Hospital (1) · Rachel Yehuda (1)
United States (4) · Canada (2) · France (1) · Israel (1)
Samuel McLean, MD (2) · Alain Brunet, Ph.D. (1) · Alain Brunet, PhD. (1) · Christopher Jones, MD (1) · Jonathan Chang, MD (1) · Rachel Yehuda, PhD (1) · Stacey House, MD (1)
2016 (1)