11 completed, 11 unknown, 3 recruiting, 1 active not recruiting. 27 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 27 | Completed 11, Unknown 11, Recruiting 3, Active not recruiting 1, Terminated 1 |
Follow Acute Lymphoblastic Leukemia: new trials by email Literature Review of Acute Lymphoblastic Leukemia trials Research Report on Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Levofloxacin Prophylaxis to Prevent First Febrile Neutropenia in Pediatric ALL During Induction Phase Levofloxacin, Placebo - Neutropenic Fever, Acute Lymphoblastic Leukemia | Phase 4 | Terminated | Gadjah Mada University | 49 | 2026-01-01 | 2026-10-01 |
| Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Malignancies Ceftazidime, Ciprofloxacin - Neutropenic Fever, Acute Lymphoblastic Leukemia | Phase 4 | Recruiting | Gadjah Mada University | 120 | 2025-06-01 | 2025-08-22 |
| Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma Dexamethasone, Vincristine, Daunorubicin - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 4 | Recruiting | St. Jude Children's Research Hospital | 850 | 2024-12-26 | 2026-07-14 |
| Hepatoprotective Measures for Children at High Risk of NAFLD Ursodeoxycholic Acid 250 Mg Oral Capsule, Omega -3 fatty acids, Physical exercise - Non Alcoholic Fatty Liver Diseases (NAFLD), Obesity and Overweight | Phase 4 | Active not recruiting | Ain Shams University | 200 | 2023-11-19 | 2025-04-09 |
| Hepatoprotective for Children and Adolescent With Acute Lymphoblastic Leukemia Dietary modification, Supplementation of omega 3 fatty acids - Leukaemia (Acute), Acute Lymphoblastic Leukemia | Phase 4 | Recruiting | Ain Shams University | 42 | 2023-11-17 | 2025-04-09 |
| A Study of Inotuzumab Ozogamicin in Chinese Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia inotuzumab ozogamicin - Acute Lymphoblastic Leukemia | Phase 4 | Completed | Pfizer | 44 | 2023-02-24 | 2025-12-03 |
| Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia Simvastatin - Strains, Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Hospital General de Mexico | 108 | 2021-11-19 | 2022-01-04 |
| A Study Of Two Inotuzumab Ozogamicin Doses in Relapsed/ Refractory Acute Lymphoblastic Leukemia Transplant Eligible Patients inotuzumab ozogamicin-dose level 2, Inotuzumab ozogamicin-dose level 1 - Leukemia, Precursor b-Cell Lymphoblastic Leukemia-Lymphoma | Phase 4 | Completed | Pfizer | 102 | 2019-07-01 | 2023-11-22 |
| Vaccinating Children After Chemotherapy Prevnar®13, Pneumovax® 23, Pediacel® - Acute Lymphoblastic Leukemia | Phase 4 | Completed | Canadian Immunization Research Network | 156 | 2015-11-16 | 2022-06-24 |
| Determinants of Mercaptopurine Toxicity in Paediatric Acute Lymphoblastic Leukemia Maintenance Therapy Mercaptopurine - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Shandong University | 500 | 2015-01-01 | 2019-04-23 |
| Study on Two Different Formulations of 6-mercaptopurine. Tablet Versus Oral Liquid Xaluprine, Puri-Nethol - Acute Lymphoblastic Leukemia, 6-mercaptopurine Therapy | Phase 4 | Unknown | Kjeld Schmiegelow | 16 | 2013-06-01 | 2018-04-20 |
| HD-Idarubicin/Etoposide Intensified Conditioning Regimen Allo-HSCT for Adult ALL IDA, TBI, CTX - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Nanfang Hospital, Southern Medical University | 100 | 2013-05-01 | 2015-10-09 |
| ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) Pharmacogenomics, Busulfan plasma level measurements - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Swiss Pediatric Oncology Group | 1000 | 2013-04-01 | 2019-04-16 |
| Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia Cyclophosphamide, Doxorubicin, Vincristine - Acute Lymphoblastic Leukemia | Phase 4 | Completed | Ruijin Hospital | 100 | 2010-12-01 | 2014-05-20 |
| PETHEMA LAL-07FRAIL: All Treatment In Fragile Patients Ph' Negative Over 55 Years vINCRISTINE, Dexamethasone, Methotrexate - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | PETHEMA Foundation | 100 | 2010-05-01 | 2022-01-19 |
| The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia 6-mercaptopurine, Methotrexate, 6-mercaptopurine, Methotrexate, Vincristine, Dexamethasone - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Sun Yat-sen University | 600 | 2008-07-01 | 2010-03-08 |
| Protocol For the Treatment Acute Lymphoblastic Leukemia With Ph 'Negative in Elderly Patients (> 55 Years) Dexamethasona, Idarubicine, ARA-C, Methotrexate - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | PETHEMA Foundation | 100 | 2007-06-30 | 2022-01-19 |
| Intensification Therapy of Mature B-ALL, Burkitt and Burkitt Like and Other High Grade Non-Hodgkin's Lymphoma in Adults Rituximab - Acute Lymphoblastic Leukemia, Non-Hodgkin's Lymphoma | Phase 4 | Unknown | University of Bologna | 25 | 2006-12-01 | 2009-09-15 |
| LAL-AR-N-2005:Study Treatment for Children High Risk Acute Lymphoblastic Leukemia Prednisolone, Daunorubicin, Vincristine - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 40 | 2005-06-01 | 2014-10-28 |
| Poly(Ethylene Glycol)(PEG)-Asparaginase During Two Treatment Courses PEG-asparaginase - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Nordic Society for Pediatric Hematology and Oncology | 85 | 2005-06-01 | 2009-09-30 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (27) · Febrile Neutropenia (3) · Leukemia (3) · Lymphoma, Non-Hodgkin (2) · Brain Neoplasms (1) · Immune System Diseases (1) · Immunoproliferative Disorders (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Lymphoid (1) · Leukemia, Myeloid, Acute (1) · Neoplasm, Residual (1) · Non-alcoholic Fatty Liver Disease (1) · Obesity (1) · Overweight (1) · Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (1)
Hematologic Diseases (27) · Hemic and Lymphatic Diseases (27) · Lymphatic Diseases (27) · Lymphoproliferative Disorders (27) · Neoplasms (27) · Neoplasms by Histologic Type (27) · Immune System Diseases (26) · Immunoproliferative Disorders (26) · Leukemia, Lymphoid (26) · Leukemia (24) · Agranulocytosis (3) · Cytopenia (3) · Leukocyte Disorders (3) · Leukopenia (3) · Neutropenia (3)
Vincristine (11) · Cytarabine (10) · Methotrexate (9) · Dexamethasone (8) · Mercaptopurine (8) · Cyclophosphamide (7) · Daunorubicin (6) · Prednisone (6) · Asparaginase (5) · Hydrocortisone (3) · Doxorubicin (2) · Etoposide (2) · Idarubicin (2) · Inotuzumab Ozogamicin (2) · Mitoxantrone (2)
PETHEMA Foundation (7) · Ain Shams University (2) · Gadjah Mada University (2) · Pfizer (2) · St. Jude Children's Research Hospital (2) · Canadian Immunization Research Network (1) · Hospital General de Mexico (1) · International BFM Study Group (1) · Kjeld Schmiegelow (1) · Nanfang Hospital, Southern Medical University (1) · Nordic Society for Pediatric Hematology and Oncology (1) · Ruijin Hospital (1) · Shandong University (1) · Sun Yat-sen University (1) · Swiss Pediatric Oncology Group (1)
Spain (8) · China (4) · United States (3) · Denmark (2) · Egypt (2) · Hungary (2) · Indonesia (2) · Italy (2) · Argentina (1) · Austria (1) · Belgium (1) · Canada (1) · Chile (1) · Czechia (1) · Germany (1)
Bastida Pilar, Dr (2) · Adolfo Martinez Tovar, PhD (1) · Ajay Vora (1) · Changgang Li, M.D. (1) · Christina Peters, Prof. MD PhD (1) · Dongbo Lai, M.D. (1) · Edina Magyarosy, MD (1) · Eduardo Dibar, MD (1) · Fatma SE Ebeid, Professor of pediatrics (1) · Franco Locatelli, Prof. MD PhD (1) · Giovanni Martinelli, MD (1) · Giuseppe Masera, MD (1) · Heather M Conklin (1)
PMID 15770833, PMID 17223475, PMID 19564304, PMID 19951974, PMID 22966847, PMID 23317527, PMID 24752047, PMID 30208456, PMID 30872105, PMID 31554370, PMID 32067048, PMID 32519032, PMID 33041718, PMID 35622074, PMID 35714315, PMID 39882642
2005 (1), 2018 (1), P30CA021765 (1), R01CA078957 (1), U01CA081445 (1)