Acute Ischemic Stroke (AIS): Clinical Trials

11 trials for Acute Ischemic Stroke (AIS), newest first

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4 completed, 4 not yet recruiting, 2 recruiting, 1 enrolling by invitation. 3 Phase 2, 2 Not applicable, 1 Phase 1, 1 Phase 3, 1 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 23Completed 2, Not yet recruiting 1
Not applicable2Completed 2
Phase 11Not yet recruiting 1
Phase 31Not yet recruiting 1
Phase 41Not yet recruiting 1

Follow Acute Ischemic Stroke (AIS): new trials by email Literature Review of Acute Ischemic Stroke (AIS) trials Research Report on Acute Ischemic Stroke (AIS)

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized Trial
Tirzepatide, Standard Medical Care (SMC) - Acute Ischemic Stroke (AIS)
Phase 2 / Phase 3Not yet recruitingyifang zhu7262026-09-202026-10-01
Acute Ischemic Stroke Involves Significant Inflammatory Response. This Prospective Cohort Study Evaluates the Predictive Value of Monocyte-, Neutrophil-, and Leukocyte-to-albumin Ratios for Stroke Severity and Functional Outcome Using NIHSS at Admission and Modified Rankin Scale During Follow-up.
Acute Ischemic Stroke (AIS)
Not yet recruitingSohag University602026-04-012026-03-17
Study to Collect Real-world Performance and Safety Data on Penumbra System® in Population With Acute Ischemic Stroke (AIS).
Penumbra System ® - Acute Ischemic Stroke (AIS)
RecruitingPenumbra Inc.2002025-11-012026-10-20
Exploration and Establishment of an Early Warning System for Futile Reperfusion - A I S
Acute Ischemic Stroke (AIS), Endovascular Thrombectomy
Enrolling by invitationXijing Hospital20002025-06-012025-07-01
Intravenous Thrombolytic Therapy for Acute Ischemic Stroke Patients with Low NIHSS and Non-disabling Deficits
Intravenous thrombolysis (alteplase and other guideline-recommended thrombolytic agents) - Thrombosis, Acute Ischemic Stroke (AIS)
Phase 4Not yet recruitingSecond Affiliated Hospital, Zhejiang University, School of Medicine3902025-03-012025-03-06
A Phase I Clinical Trial Evaluating the Safety, Tolerability and Pharmacokinetics of AAPB for Injection
Single dose, AAPB by injection, intravenous drip., Single dose, placebo, intravenous drip., Multiple dosing, AAPB for injection, intravenous drip - Acute Ischemic Stroke (AIS)
Phase 1Not yet recruitingJiangsu Kanion Pharmaceutical Co., Ltd562024-11-142024-11-08
Prospective Registry of Endovascular Thrombectomy for eXtra-Large Ischemic Stroke
medical management, endovascular thrombectomy - Acute Ischemic Stroke (AIS), Acute Ischemic Stroke From Large Vessel Occlusion
RecruitingZhongming Qiu10002024-01-202025-12-31
Study of the Safety and Neuroprotective Capacity of Scp776 in Acute Ischemic Stroke
Placebo, scp776 (1.9 mg/kg), scp776 (3.8 mg/kg) - Acute Ischemic Stroke (AIS)
Phase 2CompletedSilver Creek Pharmaceuticals1202022-10-192026-02-24
Oral Care Strategies for Stroke Patients with Dysphagia
oral care, Neuromuscular Electrical Stimulation (NMES) - Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP)
Not applicableCompletedTaipei Medical University Shuang Ho Hospital352021-12-092024-11-18
Deep Learning Enabled Endovascular Stroke Therapy Screening in Community Hospitals
Viz.AI software - Acute Ischemic Stroke (AIS)
Not applicableCompletedThe University of Texas Health Science Center, Houston4432021-01-012023-06-28
Safety and Pharmacokinetics of MCI-186 in Subjects With Acute Ischemic Stroke
MCI-186, Placebo - Acute Ischemic Stroke (AIS)
Phase 2CompletedShionogi362009-02-282026-07-16

Narrower conditions

Ischemic Stroke (11)  ·  Deglutition Disorders (1)  ·  Stroke (1)  ·  Thrombosis (1)

Broader conditions

Brain Diseases (11)  ·  Cardiovascular Diseases (11)  ·  Central Nervous System Diseases (11)  ·  Cerebrovascular Disorders (11)  ·  Nervous System Diseases (11)  ·  Vascular Diseases (11)  ·  Stroke (10)  ·  Digestive System Diseases (1)  ·  Embolism and Thrombosis (1)  ·  Esophageal Diseases (1)  ·  Gastrointestinal Diseases (1)  ·  Otorhinolaryngologic Diseases (1)  ·  Pharyngeal Diseases (1)

Interventions

Dental Care Team (1)  ·  Edaravone (1)  ·  Infusions, Intravenous (1)  ·  Injections (1)  ·  Practice Management, Medical (1)  ·  Tirzepatide (1)  ·  Tissue Plasminogen Activator (1)

Sponsors

Jiangsu Kanion Pharmaceutical Co., Ltd (1)  ·  Penumbra Inc. (1)  ·  Second Affiliated Hospital, Zhejiang University, School of Medicine (1)  ·  Shionogi (1)  ·  Silver Creek Pharmaceuticals (1)  ·  Sohag University (1)  ·  Taipei Medical University Shuang Ho Hospital (1)  ·  The University of Texas Health Science Center, Houston (1)  ·  Xijing Hospital (1)  ·  Zhongming Qiu (1)  ·  yifang zhu (1)

Countries

China (5)  ·  United States (2)  ·  Australia (1)  ·  Canada (1)  ·  Finland (1)  ·  France (1)  ·  Germany (1)  ·  Netherlands (1)  ·  Switzerland (1)  ·  Taiwan (1)  ·  United Kingdom (1)

Top investigators

Guangxiong Yuan (1)  ·  Guodong Xiao, MD.PhD (1)  ·  Marios Nikos Psychogios, Prof MD (1)  ·  Sunil Sheth, MD (1)

Results publications

PMID 20075087, PMID 24135530, PMID 25671797, PMID 26898852, PMID 27296974, PMID 28052979, PMID 28989804, PMID 29129157, PMID 29364767, PMID 29402504, PMID 30878104, PMID 31662037, PMID 31831388, PMID 34170647, PMID 34647404, PMID 35259929, PMID 36372278, PMID 36596867, PMID 37721738, PMID 37952131, PMID 39536238, PMID 39999799, PMID 40702450, PMID 40886075, PMID 41392086, PMID 41500725

NIH funding

UL1TR003167 (1)