4 completed, 1 not yet recruiting, 1 unknown. 6 Phase 2, 6 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Not yet recruiting 1, Unknown 1 |
| Phase 3 | 6 | Completed 4, Not yet recruiting 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Preoperative Gas in Eyes With Macula-off Rhegmatogenous Retinal Detachment (RRD) Intravitreal 100% C3F8 Injection, Pars plana vitrectomy or pars plana vitrectomy with scleral buckle - Retinal Detachment Rhegmatogenous | Phase 2 / Phase 3 | Not yet recruiting | Wills Eye | 190 | 2026-09-21 | 2026-10-02 |
| A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA], Glycerin 0.2%/Hypromellose 0.2%/Peg 1%/Soln,Oph,Ud - Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy | Phase 2 / Phase 3 | Unknown | Wills Eye | 80 | 2023-02-06 | 2024-07-30 |
| Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular Degeneration Dorzolamide-timolol, Artificial tears - Neovascular Age-related Macular Degeneration, Wet Macular Degeneration | Phase 2 / Phase 3 | Completed | Wills Eye | 52 | 2017-02-08 | 2020-06-19 |
| Does Adding Bevacizumab Therapy in Glaucoma Surgery Improve the Success of Needle Bleb Revisions? bevacizumab, balanced salt solution - Glaucoma | Phase 2 / Phase 3 | Completed | Wills Eye | 63 | 2009-02-01 | 2018-07-09 |
| Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery? Triesence, balanced salt solution BSS - Glaucoma | Phase 2 / Phase 3 | Completed | Wills Eye | 77 | 2009-02-01 | 2018-07-10 |
| Lucentis Versus Mitomycin C During Glaucoma Surgery Ranibizumab, Mitomycin (MMC) - Glaucoma | Phase 2 / Phase 3 | Completed | Wills Eye | 24 | 2008-01-01 | 2018-03-22 |
Glaucoma (3) · Retinal Detachment (2) · Exfoliation Syndrome (1) · Glaucoma, Angle-Closure (1) · Glaucoma, Neovascular (1) · Glaucoma, Open-Angle (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Macular Degeneration (1) · Vitreoretinopathy, Proliferative (1) · Wet Macular Degeneration (1)
Hanks Balanced Salt Solution (2) · Bevacizumab (1) · Glycerol (1) · Hypromellose Derivatives (1) · Lubricant Eye Drops (1) · Mitomycin (1) · Ophthalmic Solutions (1) · Polyethylene Glycols (1) · Ranibizumab (1) · Scleral Buckling (1) · Triamcinolone (1) · dorzolamide-timolol combination (1) · netarsudil (1)
United States (6)
Jason Hsu, MD (2) · Marlene R Moster, MD (2) · Ajay Kuriyan, MD (1) · Michael J Pro, MD (1) · Sidra Zafar, MD (1)
PMID 24794283, PMID 25019269, PMID 25826644, PMID 32239190, PMID 42568743