5 completed, 1 active not recruiting, 1 terminated. 7 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 5, Active not recruiting 1, Terminated 1 |
| Phase 2 | 3 | Completed 2, Active not recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration NG101 AAV gene therapy - Age-Related Macular Degeneration | Phase 1 / Phase 2 | Active not recruiting | Elisigen, Inc. | 20 | 2023-09-08 | 2026-09-10 |
| Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia Aceclidine + Brimonidine, Aceclidine - Eye Diseases, Presbyopia | Phase 1 | Completed | LENZ Therapeutics, Inc | 30 | 2023-07-06 | 2023-10-16 |
| A Study of AG-80308 in Dry Eye Patients AG-80308 - Dry Eye Disease | Phase 1 | Completed | Allgenesis Biotherapeutics Inc. | 84 | 2022-06-13 | 2022-11-29 |
| Study Evaluating Safety of Ragweed Mix Given by Intralymphatic Node Injections Dose Level 1, Dose Level 2, Placebo - Allergic Conjunctivitis, Allergic Rhinitis | Phase 1 | Terminated | Woodmont Pharmaceuticals, Inc. | 2 | 2017-03-30 | 2018-02-26 |
| Allergen Biocube Study Evaluating Efficacy and Safety of Nasapaque Nasal Solution in Adult Subjects With Allergic Rhinitis Nasapaque Nasal Solution, Placebo Saline Nasal Solution - Seasonal Allergic Rhinitis | Phase 1 / Phase 2 | Completed | 3E Therapeutics Corporation | 73 | 2015-03-01 | 2017-01-26 |
| Pharmacokinetics and Safety of Topical Administration of Brimonidine Tartrate Ophthalmic Solution 0.025%. Brimonidine tartrate - Hyperemia | Phase 1 | Completed | Bausch & Lomb Incorporated | 12 | 2014-02-01 | 2017-04-28 |
| Safety and Efficacy of PG101 for Dry Eye Syndrome PG101 - Dry Eye Syndrome | Phase 1 / Phase 2 | Completed | Rhodes Pharmaceuticals, L.P. | 72 | 2013-12-01 | 2014-03-05 |
Dry Eye Syndromes (2) · Eye Diseases (2) · Choroidal Neovascularization (1) · Conjunctivitis, Allergic (1) · Hyperemia (1) · Keratoconjunctivitis Sicca (1) · Macular Degeneration (1) · Presbyopia (1) · Refractive Errors (1) · Retinal Degeneration (1) · Retinal Diseases (1) · Rhinitis, Allergic (1) · Rhinitis, Allergic, Seasonal (1) · Wet Macular Degeneration (1)
Brimonidine Tartrate (2) · Gels (1) · aceclidine (1)
United States (6) · Canada (1)
Christopher D Riemann, MD (1) · Emily Schoemmell (1) · Gail Torkildsen, M.D. (1) · Joseph Ciolino, MD (1) · Kris Gameblin (1)