Makerere University: Clinical Trials

26 trials sponsored by Makerere University, newest first

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19 completed, 7 unknown. 26 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 426Completed 19, Unknown 7

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Trials (filtered) newest first · largest first

All 26 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
SEARCH CAB LA Dynamic Choice HIV Prevention Study Extension
Cabotegravir Injectable Suspension, Dynamic Choice Delivery Model, Standard of Care - HIV
Phase 4CompletedUniversity of California, San Francisco9842023-01-022026-09-24
Ivermectin-artemisinin Combination Therapy for Eradication of Malaria
Artemether/lumefantrine, Ivermectin - Malaria
Phase 4UnknownMakerere University1382022-08-042022-11-04
Optimizing Malaria Treatment for HIV-Malaria Co-infected Individuals
Artemether-lumefantrine - HIV Coinfection, Malaria
Phase 4UnknownMakerere University8882021-01-182023-01-06
Dihydroartemisinin-Piperaquine in the Context of Antiretroviral Therapy
Dihydroartemisinin-piperaquine - Drug-Drug Interaction, HIV Infection
Phase 4CompletedUniversity of California, San Francisco1942020-11-232025-03-14
Effectiveness of Tranexamic Acid in Reducing Blood Loss During Femoral Nail Surgery
Tranexamic Acid - Femoral Fractures, Hemorrhage, Surgical
Phase 4CompletedMasaka Regional Referral Hospital432018-10-012025-12-03
The Kampala Women's Bone Study
FTC/TDF and DMPA, FTC/TDF, DMPA - Bone Demineralization, Hypoestrogenism
Phase 4CompletedUniversity of Washington5002018-05-152024-06-17
Alignment of PrEP Use With HIV Risk in Young Women and Men
Daily oral PrEP - Pre-Exposure Prophylaxis, Sexually Transmitted Diseases, Bacterial
Phase 4CompletedUniversity of Washington2122018-05-012025-06-17
Efficacy of Umbilical Cord Cleansing With a Single Application of 4% Chlorhexidine for the Prevention of Newborn Infections in Uganda: a Randomized Controlled Trial
Intervention arm: 4% chlorhexidine - Omphalitis, Septicaemia
Phase 4CompletedMakerere University47602016-07-012025-04-06
Strategies for the Prevention of Hepatitis B Among HIV Infected Patients in Uganda
Hepatitis B vaccine - HIV/AIDS and Infections
Phase 4CompletedFred Hutchinson Cancer Center1322015-11-012019-01-25
Single Dose Ceftriaxone and Metronidazole Versus Multiple Doses for Antibiotic Prophylaxis at Elective Cesarean Section.
Single dose antibiotic, Multiple dose antibiotic - Post Operative Infections
Phase 4CompletedMakerere University1742015-09-012016-04-13
CAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENT
caudal bupivacaine, intravenous morphine - Post Operative Pain
Phase 4CompletedMakerere University702015-07-012016-04-11
Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers
Low dose ketamine, Morphine - Sickle Cell Crisis, Acute Pain
Phase 4CompletedMakerere University2402015-06-012016-08-03
A Pharmacokinetic Evaluation of Etonogestrel (ENG) Implant and Antiretroviral Therapy
Etonogestrel - HIV, Contraception
Phase 4CompletedUniversity of Pittsburgh602014-10-012017-09-14
Artemether/ Lumefantrine: A Study of the Effect of Local Food on Pharmacokinetics and Population Pharmacokinetics
Food - Malaria, Falciparum
Phase 4UnknownMakerere University702013-09-012014-05-28
Task Sharing to Improve Post Abortion Care at District Health Care Level- Trial in Uganda
misoprostol by midwife - Pregnancy
Phase 4CompletedKarolinska Institutet10102013-04-012014-08-29
Evaluation of the Pharmacokinetics of Antituberculosis Drugs and Tuberculosis Treatment Outcomes
Rifampicin, Isoniazid, Ethambutol, Pyrazinamide - AIDS With Tuberculosis
Phase 4UnknownMakerere University4002013-02-012015-04-13
Operational Research for Cryptococcal Antigen Screening
Fluconazole - Cryptococcal Meningitis, Cryptococcus Neoformans
Phase 4CompletedUniversity of Minnesota30492012-07-012020-06-04
The Effect of Ketamine on Production of Inflammatory Markers in Post Operative Patients in Mulago Hospital
Ketamine - Post Operative Inflammatory Marker Levels
Phase 4UnknownMakerere University302011-04-012011-04-20
Cryptococcal Optimal ART Timing Trial
efavirenz, nucleoside - Cryptococcal Meningitis, HIV Infections
Phase 4CompletedUniversity of Minnesota1772010-11-012020-06-09
Interactions Between Antiretrovirals (ARVs) and Combined Oral Contraceptives (COCs)
ETHINYL ESTRADIOL AND LEVOGESTREL - HIV/AIDS, HIV Infections
Phase 4CompletedFHI 3603702009-03-012011-10-31

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Conditions studied

HIV Infections (9)  ·  Acquired Immunodeficiency Syndrome (5)  ·  Malaria (3)  ·  Tuberculosis (3)  ·  Cryptococcosis (2)  ·  Meningitis, Cryptococcal (2)  ·  Acute Pain (1)  ·  Blood Loss, Surgical (1)  ·  Bone Demineralization, Pathologic (1)  ·  Femoral Fractures (1)  ·  Infections (1)  ·  Malaria, Falciparum (1)  ·  Pain, Postoperative (1)  ·  Sexually Transmitted Diseases, Bacterial (1)  ·  Toxemia (1)

Interventions

Artemether, Lumefantrine Drug Combination (6)  ·  Nevirapine (3)  ·  efavirenz (3)  ·  stavudine, lamivudine, nevirapine drug combination (3)  ·  Ketamine (2)  ·  Lamivudine (2)  ·  Rifampin (2)  ·  Stavudine (2)  ·  Anti-Bacterial Agents (1)  ·  Chlorhexidine (1)  ·  Ethambutol (1)  ·  Ethinyl Estradiol (1)  ·  Euvax-B (1)  ·  Fluconazole (1)  ·  Food (1)

Countries

Uganda (26)  ·  South Africa (2)  ·  Kenya (1)

Top investigators

Concepta Merry, PhD (2)  ·  Renee Heffron, PhD, MPH (2)  ·  Adeodata Kekitiinwa (1)  ·  Ambrose O Talisuna, PhD (1)  ·  Barbara Castelnuovo, MD, PhD (1)  ·  Catherine A Chappell, MD (1)  ·  Celestino Obua, PhD (1)  ·  Concepta A Merry, PhD (1)  ·  Concepta A. Merry, PhD (1)  ·  Corey Casper, MD (1)  ·  David B Meya, MMed (1)  ·  David R Bangsberg, MD,MPH (1)  ·  David R Boulware, MD, MPH (1)  ·  Deogratias Munube, MMed (1)  ·  Diane Havlir, MD (1)

Results publications

PMID 25297720, PMID 39630076, PMID 19096711, PMID 19622553, PMID 21047828, PMID 22316571, PMID 23728678, PMID 24088680, PMID 24963568, PMID 25817472, PMID 26872219, PMID 28692531, PMID 28701228, PMID 28928173, PMID 29062346, PMID 29162063, PMID 29514175, PMID 29794277, PMID 30325463, PMID 30399034, PMID 30910890, PMID 31299074, PMID 31319498, PMID 31504335, PMID 32843994, PMID 33661539, PMID 34061352, PMID 36892945, PMID 39395424, PMID 39972326, PMID 41762058, PMID 41981532

NIH funding

R01HD068174 (1), R01HD089843 (1), R21HD098923 (1), U01AI089244 (1), U01AI150510 (1), U01GH000517 (1)