6 completed, 1 terminated, 1 unknown. 4 Phase 1, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Not applicable | 2 | Completed 2 |
Follow Jules Desmeules: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetics of Dexamethasone in COVID-19 Obese Patients Capillary blood sampling - Obesity | Completed | Jules Desmeules | 30 | 2021-02-02 | 2021-08-09 | |
| Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol Dextrometorphan, Genotyping by single nulcetoide polymorphism. - Interaction, Pain | Unknown | University Hospital, Geneva | 172 | 2019-11-04 | 2022-01-19 | |
| Endobiotics for Phenotyping of Human Cytochrome P450 Enzymes Dextromethorphan 5 MG, Paroxetine 10Mg Tablet, Paroxetine 20Mg Tablet - Healthy | Not applicable | Completed | Jules Desmeules | 40 | 2019-01-01 | 2022-01-04 |
| Exploring the Role of the GABAergic Modulation in Pain Transmission in Human NDMC 20mg, NDMC60mg, Clonazepam 1.5mg - Neuropathic Pain | Phase 1 | Completed | Jules Desmeules | 56 | 2017-03-30 | 2019-04-19 |
| Impact of Genetic Polymorphism on Drug-Drug Interactions Involving CYP2D6 Dextromethorphan 5 MG, Tramadol 10 mg, Duloxetine 60mg - Healthy | Not applicable | Completed | Jules Desmeules | 34 | 2016-07-01 | 2019-04-19 |
| Impact of Antiretroviral Treatment on Pharmacokinetics and Pharmacodynamics of Thienopyridines in Healthy Volunteers and HIV Patients Clopidogrel 300Mg Tablet, Prasugrel 60Mg - Hiv | Phase 1 | Terminated | Jules Desmeules | 21 | 2015-06-01 | 2017-09-11 |
| Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail Caffeine, omeprazole, flurbiprofen, dextromethorphan, midazolam, Bupropion, Fexofenadine - Drug Interaction | Phase 1 | Completed | Jules Desmeules | 30 | 2014-11-01 | 2017-02-07 |
| Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot Cocktail probe drugs - Healthy Volunteers | Phase 1 | Completed | Jules Desmeules | 10 | 2012-11-01 | 2014-09-16 |
Acquired Immunodeficiency Syndrome (1) · Chronic Pain (1) · Neuralgia (1) · Obesity (1) · Pain (1)
Dextromethorphan (4) · Bupropion (2) · Caffeine (2) · Flurbiprofen (2) · Midazolam (2) · Omeprazole (2) · Paroxetine (2) · Tablets (2) · fexofenadine (2) · Clonazepam (1) · Clopidogrel (1) · Duloxetine Hydrochloride (1) · Prasugrel Hydrochloride (1) · Tramadol (1)
Switzerland (7)
Jules A Desmeules, Pr (2) · Caroline Samer, Doctor (1) · Youssef Daali, Pr. (1)
2016 (1), 2018 (1), 2019 (1)