50 completed, 2 unknown, 2 withdrawn, 1 enrolling by invitation. 57 Phase 1, 12 Phase 2.
Follow Water: new trials by email Literature Review of Water trials Research Report on Water
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Racecadotril for Organ Injury in Sepsis Patients Racecadotril, Water (Placebo) - Sepsis | Phase 1 / Phase 2 | Enrolling by invitation | Zhujiang Hospital | 44 | 2026-05-06 | 2026-05-28 |
| Next Generation T-cell Vaccine Against Coronavirus Disease (COVID-19) PepGNP-COVID19 (One vaccination), Water for injection (One vaccination), PepGNP-COVID19 (Two vaccinations) - Coronavirus, SARS-CoV-2 Infection | Phase 1 / Phase 2 | Not yet recruiting | Gylden Pharma Ltd | 110 | 2025-09-01 | 2025-02-24 |
| A Study to Evaluate Two Vonoprazan Orally Disintegrating Tablet Formulations Administered Without Water or Mixed With Water and Administered Via a Syringe Relative to the Vonoprazan Tablet in Healthy Participants Vonoprazan ODT-1 or ODT-2 without Water, Vonoprazan ODT-1 or ODT-2 with Water, Vonoprazan (Reference) - Healthy Volunteers | Phase 1 | Completed | Phathom Pharmaceuticals, Inc. | 25 | 2025-02-14 | 2025-12-19 |
| The Effect of Gum Arabic (GA) on Residual Renal Function in Adult Dialysis Patients in Abu Dhabi Gum Arabic, Water - End Stage Renal Disease (ESRD) | Phase 1 / Phase 2 | Recruiting | Abu Dhabi Health Services Company | 40 | 2025-02-03 | 2025-02-20 |
| Graded Insulin Suppression Test P&F Insulin regular, 2.0-3.2 mU/m2/min (euinsulinemia), Insulin regular, 32 mU/m2/min (hyperinsulinemia), Octreotide Acetate, 6-45 ng/kg/min - Insulin Resistance, Hyperinsulinemia | Phase 1 | Completed | Columbia University | 20 | 2024-09-16 | 2026-10-16 |
| A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants Xeruborbactam, Cefiderocol, Xeruborbactam/Cefiderocol - Bacterial Infections | Phase 1 | Completed | Qpex Biopharma, Inc. | 60 | 2024-09-04 | 2025-11-28 |
| Metabolic Changes in Healthy Subjects with Acute Binge Drink Vodka, water - Binge Drinking, Liver Injury | Phase 1 | Completed | Zhejiang Chinese Medical University | 40 | 2024-04-27 | 2025-01-22 |
| Colostrum From MERS-CoV Seropositive Camels for SARS-CoV-2 Infection - a Placebo-controlled Randomized Trial. Colostrum Nasal Spray, Water for injection - COVID 19 | Phase 1 / Phase 2 | Completed | Hadassah Medical Organization | 43 | 2023-05-01 | 2025-03-04 |
| Biofeedback and Hydrogen Water as Treatments for Chronic Fatigue Syndrome Heart Rhythm Biofeedback, Hydrogen Water, Combined treatment: Heart rhythm biofeedback plus hydrogen water - Chronic Fatigue Syndrome | Phase 1 | Unknown | Stony Brook University | 39 | 2022-05-23 | 2022-05-31 |
| Tolerability and Efficacy of RJX in Patients With COVID-19 Rejuveinix (RJX) Active Comparator, Placebo Comparator - COVID-19, Acute Respiratory Distress Syndrome | Phase 1 / Phase 2 | Unknown | Reven Pharmaceuticals, Inc. | 237 | 2021-03-25 | 2022-03-15 |
| Study to Evaluate the Pharmacokinetic Characteristics and Safety of IN-C004 in Healthy Volunteers IN-C004 with water, IN-C004 without water, K-CAB tab. with water - Healthy | Phase 1 | Completed | HK inno.N Corporation | 48 | 2021-01-18 | 2021-03-29 |
| Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole GSK3915393 Capsules, GSK3915393 Solution for Infusion, Placebo capsules - Celiac Disease, Coeliac Disease | Phase 1 | Completed | GlaxoSmithKline | 65 | 2020-11-04 | 2023-05-09 |
| Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans Ketamine, Normal Saline - Post-Traumatic Stress Disorders, Major Depressive Disorder | Phase 1 | Completed | University of Minnesota | 67 | 2019-09-30 | 2025-06-27 |
| A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis AMY-101, Water for injection - Gingivitis | Phase 1 / Phase 2 | Completed | Amyndas Pharmaceuticals S.A. | 39 | 2019-07-22 | 2021-02-21 |
| Bioequivalence Study of Brexpiprazole Orally Disintegrating Tablets (ODT) 2mg Brexpiprazole ODT 2mg with water, Brexpiprazole ODT 2mg without water, Brexpiprazole conventional tablet 2mg - Healthy Adult Male | Phase 1 | Completed | Otsuka Pharmaceutical Co., Ltd. | 21 | 2019-03-27 | 2021-07-20 |
| Evaluating Predictive Methods & Product Performance in Healthy Adults for Pediatric Patients, A Case Study: Furosemide Water, Parmalat™ Whole Milk, Similac Pro-Advance™ - Medication Absorption | Phase 1 | Withdrawn | Yale University | 2018-12-31 | 2019-01-18 | |
| Influence of Cola on the Absorption of the HCV Agent Velpatasvir in Combination With PPI Omeprazole. velpatasvir - Hepatitis C, Swallowing Disorder | Phase 1 | Completed | Radboud University Medical Center | 11 | 2018-08-01 | 2020-10-19 |
| Evaluation of Bioavailability and Metabolism of Diet Phenolic Compounds Administration of olive oil, Administration of red wine, Combination of red wine and olive oil - Healthy | Phase 1 | Completed | Parc de Salut Mar | 20 | 2018-07-09 | 2020-03-05 |
| Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of Celecoxib Celecoxib, Moxifloxacin, Water - Qt Interval, Variation in | Phase 1 | Completed | Samsung Medical Center | 28 | 2017-06-30 | 2019-01-30 |
| A Study to Compare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are Administered Ticagrelor granule, Ticagrelor pediatric tablets, Ticagrelor pediatric tablets suspended in water - Sickle Cell Disease | Phase 1 | Completed | AstraZeneca | 44 | 2017-05-12 | 2017-08-02 |
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COVID-19 (3) · Diabetes Mellitus (3) · Obesity (3) · Anemia, Sickle Cell (2) · Anxiety Disorders (2) · Insulin Resistance (2) · Acute Coronary Syndrome (1) · Bacterial Infections (1) · Behavioral Symptoms (1) · Binge Drinking (1) · Bone Diseases, Metabolic (1) · Brain Injuries, Traumatic (1) · Celiac Disease (1) · Coronavirus Infections (1) · Deglutition Disorders (1)
AstraZeneca (4) · Parc de Salut Mar (3) · LEO Pharma (2) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (2) · University Hospital, Basel, Switzerland (2) · University of Toronto (2) · Vivozon, Inc. (2) · Abu Dhabi Health Services Company (1) · Actavis Inc. (1) · Amyndas Pharmaceuticals S.A. (1) · Aquestive Therapeutics (1) · Cerecin (1) · Columbia University (1) · GlaxoSmithKline (1) · Gylden Pharma Ltd (1)
United States (18) · Canada (4) · Germany (3) · South Korea (3) · Spain (3) · China (2) · Denmark (2) · Japan (2) · United Kingdom (2) · Australia (1) · Austria (1) · Brazil (1) · Israel (1) · Kenya (1) · Netherlands (1)
Rainard Fuhr, Dr. med. (3) · Christoph Beglinger, MD (2) · G. Harvey Anderson, Ph.D. (2) · Jae Yong Chung, MD, PhD (2) · Alan S. Marion, MD, PhD (1) · Alberto R Edison, MD (1) · Annelize Koch, Dr. (1) · Christine A Becker, PhD (1) · Colleen Hunsaker, D.O. (1) · Cristina S Albott, MD, MA (1) · David G Bailey, BScPhm, PhD (1) · David G. Soergel, MD (1)
PMID 15269196, PMID 17999333, PMID 18201934, PMID 19479191, PMID 20878941, PMID 22297835, PMID 23241359, PMID 23813302, PMID 24022265, PMID 24122908, PMID 24372304, PMID 24703280, PMID 24733463, PMID 25168404, PMID 25515208, PMID 25724154, PMID 25801942, PMID 26336641, PMID 28589039, PMID 28880867, PMID 28961714, PMID 31140114, PMID 31313296, PMID 31564512, PMID 32328307, PMID 33435475, PMID 33896052, PMID 34483038, PMID 34618684, PMID 35208961, PMID 35603590, PMID 36092515, PMID 36671523, PMID 3692386, PMID 41118352, PMID 6683227
R01MH073856 (1)