8 completed, 1 recruiting, 1 withdrawn. 10 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 8, Recruiting 1, Withdrawn 1 |
| Phase 2 | 7 | Completed 5, Recruiting 1, Withdrawn 1 |
Follow Vehicle Control: new trials by email Literature Review of Vehicle Control trials Research Report on Vehicle Control
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate ENERGI-F705 Tablets in Healthy Volunteers ENERGI-F705 Tablets 60 mg, ENERGI-F705 Tablets 120 mg, Vehicle Control - Health Adult Subjects | Phase 1 | Completed | Energenesis Biomedical Co., Ltd. | 24 | 2025-02-24 | 2026-06-16 |
| CBD for Knee Osteoarthritis Cannabidiol (CBD) Extract, Placebo - Osteoarthritis, Knee | Phase 1 / Phase 2 | Recruiting | University of Florida | 30 | 2024-06-14 | 2025-09-17 |
| Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects CSB-001 Ophthalmic Solution 0.1%, Vehicle Control - Neurotrophic Keratitis | Phase 1 / Phase 2 | Completed | Claris Biotherapeutics, Inc. | 131 | 2021-08-24 | 2026-05-13 |
| A Study of ORTD-1 in Patients Hospitalized With COVID-19 Related Pneumonia ORTD-1 low dose, ORTD-1 mid dose, ORTD-1 high dose - COVID-19 | Phase 1 / Phase 2 | Withdrawn | Oryn Therapeutics, LLC | 2021-04-01 | 2021-06-14 | |
| Phase I Study of Progerinin in Healthy Volunteers Progerinin, Placebo - Hutchinson-Gilford Progeria Syndrome, Werner Syndrome | Phase 1 | Completed | PRG Science & Technology Co., Ltd. | 64 | 2020-08-24 | 2021-09-22 |
| A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 APL-9, Vehicle Control - COVID, Covid-19 | Phase 1 / Phase 2 | Completed | Apellis Pharmaceuticals, Inc. | 72 | 2020-05-28 | 2022-03-23 |
| A Study of the Safety, Engraftment, and Action of Multi-Dosed NB01 in Adults With Moderate Acne NB01, Vehicle Control - Acne Vulgaris | Phase 1 | Completed | Naked Biome, Inc. | 36 | 2018-11-01 | 2020-08-03 |
| Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease CAM-101 10%, Vehicle Control, CAM-101 30% - Dry Eye, Graft-versus-host-disease | Phase 1 / Phase 2 | Completed | Cambium Bio Limited | 64 | 2018-05-01 | 2026-06-12 |
| A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc Degeneration Intradiscal rhGDF-5, Vehicle control - Early Lumbar Disc Degeneration | Phase 1 / Phase 2 | Completed | DePuy Spine | 31 | 2010-06-01 | 2016-02-26 |
| Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels rhu-pGelsolin, Placebo - Low Gelsolin, Trauma | Phase 1 / Phase 2 | Completed | Critical Biologics Corporation | 40 | 2008-03-01 | 2010-09-29 |
COVID-19 (2) · Acne Vulgaris (1) · Acute Lung Injury (1) · Burns (1) · Coronavirus Infections (1) · Dry Eye Syndromes (1) · Graft vs Host Disease (1) · Infections (1) · Intervertebral Disc Degeneration (1) · Meretoja syndrome (1) · Motor Activity (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Pain (1) · Peritonitis (1)
Apellis Pharmaceuticals, Inc. (1) · Cambium Bio Limited (1) · Claris Biotherapeutics, Inc. (1) · Critical Biologics Corporation (1) · DePuy Spine (1) · Energenesis Biomedical Co., Ltd. (1) · Naked Biome, Inc. (1) · Oryn Therapeutics, LLC (1) · PRG Science & Technology Co., Ltd. (1) · University of Florida (1)
United States (7) · Brazil (1) · Canada (1) · Hong Kong (1) · South Korea (1) · Taiwan (1)
Alpesh Amin, MD (1) · Edmund K Waller, MD PhD (1) · Emma Taylor, MD (1) · Richard C Straube, MD (1) · Selene Tam, PhD (1) · Wai M Chan, MBBS (1)
PMID 22859988, PMID 23337890, PMID 23631911, PMID 27303708, PMID 33945627, PMID 35266655