404 completed, 94 unknown, 72 recruiting, 25 terminated. 572 Not applicable, 41 Phase 2, 24 Phase 3, 22 Phase 1, 11 Phase 4.
Follow Treatment as usual: new trials by email Literature Review of Treatment as usual trials Research Report on Treatment as usual
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Hope@School Prevention Program Hope@School, Treatment as usual - Mental Health Wellness 1 | Not applicable | Not yet recruiting | Karolinska Institutet | 3220 | 2027-01-01 | 2024-04-11 |
| Facilitating Transition to Recommended PTSD Treatment Treatment As Usual, New Health Services Intervention - PTSD | Not applicable | Not yet recruiting | VA Office of Research and Development | 40 | 2026-12-01 | 2026-08-18 |
| Open-label Placebo for Pain Management in Adolescents and Young Adults Undergoing Bernese Periacetabular Osteotomy Open-Label Placebo, Treatment as usual - Periacetabular Osteotomy, Opiates | Not applicable | Recruiting | University of California, San Francisco | 64 | 2026-12-01 | 2026-04-29 |
| Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary Fibrosis Therapeutic Plasma Exchange, Rituximab, Intravenous immunoglobulin - Idiopathic Pulmonary Fibrosis | Phase 2 | Not yet recruiting | University of Alabama at Birmingham | 52 | 2026-12-01 | 2026-10-20 |
| Effectiveness and Security Testing of a Mobile App Mobile app, Treatment as usual - Attention Deficit Disorder With Hyperactivity | Not applicable | Not yet recruiting | Consorci Sanitari del Maresme | 80 | 2026-10-01 | 2024-09-19 |
| Pain and Smoking Study 2.0: A Randomized Clinical Trial of Smoking Cessation Among Veterans With Chronic Pain PASS2, Treatment as Usual - Smoking, Pain | Not applicable | Recruiting | VA Office of Research and Development | 220 | 2026-09-21 | 2026-09-29 |
| Culturally Centered CBT Protocol for Suicidal Behaviors Among Youth in Mexico City Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as usual - Suicidal Ideation/Behavior | Not applicable | Not yet recruiting | Bradley Hospital | 60 | 2026-09-01 | 2026-07-13 |
| Written Exposure in Substance Treatment (WEST 3.0): Randomized Controlled Trial Written Exposure Therapy, Treatment as Usual - Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD) | Not applicable | Not yet recruiting | Potomac Health Foundations | 400 | 2026-09-01 | 2026-08-24 |
| Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches & Across INcarceration Settings Virtual Peer Recovery Coaching, Treatment as Usual - Substance Use | Not applicable | Recruiting | Emory University | 550 | 2026-09-01 | 2026-08-17 |
| The ConCERN Intervention for Loved Ones of Those With Opioid Use Disorder ConCERN intervention, Treatment as Usual - Opioid Use Disorder | Not applicable | Not yet recruiting | University of Michigan | 700 | 2026-09-01 | 2026-08-31 |
| BIG Chicago: A Trial of Basic Income Guarantee for Young People Living With HIV Treatment As Usual, BIG + Treatment As Usual - HIV, Financial Stress | Not applicable | Recruiting | University of Chicago | 304 | 2026-07-29 | 2026-08-06 |
| Implementing DBT in Short-Term SUD-treatment DBT-informed milieu therapy, Treatment as usual - Substance Abuse Disorder, Dialectical Behavior Therapy | Not applicable | Enrolling by invitation | Helse Møre og Romsdal HF | 82 | 2026-07-01 | 2026-09-25 |
| Internet-delivered Emotion Regulation Individual Therapy or Adolescents (IERITA) With Self-injury Within Child and Adolescent Mental Health Services Adaptable IERITA, Standard IERITA, Treatment as usual - Nonsuicidal Self-Injury, Self-Harm | Not applicable | Recruiting | Karolinska Institutet | 341 | 2026-05-22 | 2026-06-08 |
| Adapting a Brief Suicide Intervention for Pediatric Primary Care: Enhancing Uptake and Impact Pilot Intervention, Treatment as Usual - Suicide Prevention | Not applicable | Recruiting | University of Washington | 48 | 2026-05-04 | 2026-07-16 |
| Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors Tele-delivered Behavioral Activation by lay counselors after Stroke (Tele-BA-S), Treatment as Usual - Post-stroke Depression, Subthreshold Depression | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 350 | 2026-04-10 | 2026-04-28 |
| Virtual Reality Supported Rehabilitation for Children's Executive and Metaphonological Skills vrrs, Treatment as usual - Attention Deficit Hyperactivity Disorder (ADHD) | Not applicable | Not yet recruiting | IRCCS Centro Neurolesi Bonino Pulejo | 50 | 2026-03-31 | 2026-02-23 |
| A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder Approach Bias Modification, Treatment as usual - Training for Cocaine Use Disorder | Not applicable | Recruiting | ASST Fatebenefratelli Sacco | 60 | 2026-03-31 | 2025-12-24 |
| Effectiveness- Implementation Trial of the Function-Based Elopement Treatment Function-Based Elopement Treatment, Treatment as Usual - Autism Spectrum Disorder | Not applicable | Recruiting | Emory University | 50 | 2026-03-30 | 2026-06-18 |
| Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care - Chronic Pain, Back Pain | Not applicable | Recruiting | University of Colorado, Denver | 360 | 2026-03-27 | 2026-03-31 |
| VR-relaxation for ECT-related Anxiety VR-based relaxation, Breathing exercises, Treatment as usual - ECT-related Anxiety | Not applicable | Enrolling by invitation | Universitair Ziekenhuis Brussel | 20 | 2026-03-12 | 2026-04-22 |
Showing 20 of 661. Sign in to see all of them.
Depression (112) · Anxiety Disorders (67) · Substance-Related Disorders (60) · Stress Disorders, Post-Traumatic (47) · Schizophrenia (44) · Psychotic Disorders (40) · Depressive Disorder, Major (31) · Mental Disorders (29) · Psychological Well-Being (26) · Suicide (24) · Chronic Pain (22) · Autism Spectrum Disorder (21) · Attention Deficit Disorder with Hyperactivity (20) · Alcoholism (19) · Opioid-Related Disorders (19)
VA Office of Research and Development (26) · Medical University of South Carolina (15) · Karolinska Institutet (14) · University of Washington (13) · University of Pittsburgh (12) · Centre for Addiction and Mental Health (11) · Norwegian University of Science and Technology (11) · University of South Florida (8) · Brown University (7) · St. Olavs Hospital (7) · NYU Langone Health (6) · The University of Hong Kong (6) · The University of Texas Health Science Center at San Antonio (6) · University of Colorado, Denver (6) · University of North Carolina, Chapel Hill (6)
United States (292) · Norway (41) · Canada (38) · United Kingdom (33) · Sweden (28) · Denmark (22) · Germany (19) · Spain (19) · Italy (10) · Netherlands (10) · Switzerland (10) · China (9) · Finland (9) · France (8) · Hong Kong (7)
Jennifer Dahne, PhD (4) · Eric A Storch, Ph.D. (3) · Alejandro Interian, PhD (2) · Daniel Brandeis, PhD (2) · Dawn I. Velligan, PhD (2) · Gloria Wong, PhD (2) · Jennifer N Felder, PhD (2) · Johan Bjureberg, PhD (2) · John W Burns, PhD (2) · Jun Chen, M.D., Ph.D (2) · Kari Glavin, PhD (2) · Maria A Zetterqvist, PhD (2) · Mohammad Diab, MD (2) · Monali Malvankar, PhD (2) · Nasim Chaudhry (2)
PMID 32368793, PMID 27488181, PMID 34874888, PMID 38819882, PMID 33677832, PMID 32880104, PMID 33884617, PMID 34693989, PMID 40342086, PMID 42755118, PMID 10125443, PMID 11016567, PMID 16717171, PMID 17267779, PMID 19212970, PMID 19221871, PMID 19232020, PMID 19470315, PMID 19829198, PMID 20146834, PMID 20178636, PMID 20483968, PMID 20946651, PMID 21075957, PMID 21159452, PMID 21185685, PMID 21190455, PMID 21367351, PMID 21464362, PMID 21722028, PMID 21762829, PMID 21896369, PMID 21967492, PMID 21969420, PMID 21981909, PMID 22074851, PMID 22103890, PMID 22152230, PMID 22230825, PMID 22296967, PMID 22304968, PMID 22349843, PMID 22403146, PMID 22404963, PMID 2245752, PMID 22566583, PMID 22573504, PMID 22657748, PMID 22781019, PMID 22805901
2019 (5), P30AG022845 (2), P50MH115838 (2), RM1DA055437 (2), 1IK2HX003339-01A2 (1), 1IK2RX003821-01A1 (1), 2015 (1), 2016 (1), 2017 (1), 2018 (1), 2023 (1), 5RC2DA028864 (1), 5SC1MH090599 (1), 5UG1DA040316-05 (1), D43TW009114 (1)