17 completed, 6 recruiting, 5 not yet recruiting, 3 withdrawn. 31 Not applicable, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 31 | Completed 15, Recruiting 6, Not yet recruiting 5, Unknown 2, Withdrawn 2, Active not recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multiparameter Optimized tES for Memory in Aging Transcranial electrical stimulation - Healthy Aging | Not applicable | Withdrawn | Medical University of South Carolina | 2026-12-31 | 2026-02-25 | |
| Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking TES-TI with hdEEG - Transcranial Electric Stimulation | Not applicable | Recruiting | University of Wisconsin, Madison | 24 | 2026-10-01 | 2026-09-29 |
| Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia Primary Motor Cortex Stimulation, Occipital Lobe Stimulation - Fibromyalgia (FM) | Not applicable | Recruiting | Pulkit Grover | 50 | 2026-09-09 | 2026-10-21 |
| Closed-loop tES-non-invasive Stimulation Transcranial low intensity focused ultrasound (FUS), transcranial electrical stimulation, Magnetic Resonance Imaging - Closed-loop Brain Stimulation | Not applicable | Not yet recruiting | University of Nottingham | 30 | 2026-09-01 | 2026-08-19 |
| Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation - Anxiety, PTSD | Not applicable | Active not recruiting | Tactical Mind Research Coalition, Inc. | 240 | 2026-08-01 | 2026-09-16 |
| Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation Transcranial Electrical Stimulation, Transcranial Magnetic Stimulation, TES + TMS - Cortical Excitability, Healthy | Not applicable | Not yet recruiting | Carnegie Mellon University | 25 | 2026-07-01 | 2026-06-09 |
| Enhancing Attention in Elderly Using a Brain-Computer-Interface transcranial electrical stimulation, Mindfulness Meditation - Mild Cognitive Impairment (MCI) | Not applicable | Recruiting | University of Texas at Austin | 100 | 2026-07-01 | 2026-07-27 |
| Transcranial Electrical Stimulation for Noninvasive Study of Menopausal/Perimenopausal Symptoms Transcranial Electrical Stimulation - Menopausal Depression, Menopause Hot Flashes | Not applicable | Not yet recruiting | Carnegie Mellon University | 50 | 2026-02-01 | 2026-01-29 |
| Early Neuromodulation in Traumatic Brain Injury transcranial electrical stimulation, Sham Comparator - Traumatic Brain Injury (TBI) Patients | Not applicable | Recruiting | University of Cincinnati | 60 | 2025-06-16 | 2026-06-03 |
| tES Modalities for the Treatment of ADHD transcranial electrical stimulation - Attention Deficit Disorder With Hyperactivity, Neurodevelopmental Disorders | Not applicable | Completed | The National Brain Mapping Laboratory (NBML) | 45 | 2025-03-30 | 2026-08-04 |
| The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders Transcranial Magnetic Stimulation - Insomnia Chronic, Narcolepsy | Not applicable | Recruiting | Second Affiliated Hospital of Soochow University | 20 | 2025-02-01 | 2025-02-14 |
| Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training Alone for the Treatment of Accommodation Dysfunction Transcranial Electrical Stimulation, Visual Training - Presbyopia, Esotropia | Not applicable | Not yet recruiting | Eye & ENT Hospital of Fudan University | 100 | 2024-12-31 | 2024-12-05 |
| Clinical Multicenter Randomized Controlled Study of Non-invasive Brain Oscillation Modulation in the Treatment of AD-MCI Patients Transcranial electrical stimulation - AD-MCI | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 124 | 2024-09-01 | 2024-06-24 |
| Gamma tACS to Improve Cognitive Function in Mild Cognitive Impairment transcranial electrical stimulation - Mild Cognitive Impairment (MCI) | Not applicable | Completed | The National Brain Mapping Laboratory (NBML) | 30 | 2024-03-02 | 2026-08-07 |
| tDCS and Inhibitory Control in PTSD tDCS - Post Traumatic Stress Disorder | Not applicable | Completed | Gopalkumar Rakesh | 38 | 2023-10-27 | 2025-01-16 |
| Effect of Transcranial Direct Current Stimulation on the Voice Transcranial direct current stimulation - Voice and Resonance Disorders, Transcranial Direct Current Stimulation | Not applicable | Completed | Universidade Federal de Pernambuco | 16 | 2023-03-30 | 2024-08-15 |
| Home Sleep Therapy for Older Adults With MCI Transcranial Electrical Stimulation - Mild Cognitive Impairment, Sleep | Not applicable | Recruiting | Brain Electrophysiology Laboratory Company | 60 | 2023-02-08 | 2025-02-17 |
| Developing an EEG Probe for Studying and Modulating Cognitive Control Transcranial Electrical stimulation, Transcutaneous direct current stimulation - Post-stroke Depression | Not applicable | Completed | University of Cincinnati | 30 | 2022-09-28 | 2024-06-27 |
| Shaping Motor Neural Functioning of Developmental Stuttering to Improve Fluency transcranial Electrical Stimulation, Speech Therapy - Stuttering | Not applicable | Completed | IRCCS San Camillo, Venezia, Italy | 24 | 2022-04-02 | 2024-10-02 |
| Home-based Transcranial Stimulation in the Treatment of Patients With Refractory Chronic Pain Transcranial electrical stimulation - Chronic Pain | Not applicable | Unknown | University of Santiago de Compostela | 120 | 2022-01-01 | 2021-10-29 |
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Anxiety Disorders (4) · Cognitive Dysfunction (4) · Depression (3) · Attention Deficit Disorder with Hyperactivity (2) · Bipolar Disorder (2) · Chronic Pain (2) · Fibromyalgia (2) · Psychotic Disorders (2) · Stress Disorders, Post-Traumatic (2) · Arthritis (1) · Brain Injuries, Traumatic (1) · Cervical Dystonia, Primary (1) · Communication Disorders (1) · Depressive Disorder, Major (1) · Esotropia (1)
Beth Israel Deaconess Medical Center (2) · Brain Electrophysiology Laboratory Company (2) · Carnegie Mellon University (2) · Istanbul University (2) · The National Brain Mapping Laboratory (NBML) (2) · University of Cincinnati (2) · University of Minnesota (2) · Eye & ENT Hospital of Fudan University (1) · Gopalkumar Rakesh (1) · IRCCS San Camillo, Venezia, Italy (1) · Medical University of South Carolina (1) · Pulkit Grover (1) · Second Affiliated Hospital of Soochow University (1) · Tactical Mind Research Coalition, Inc. (1) · The University of New South Wales (1)
United States (18) · China (3) · Iran (2) · Turkey (Türkiye) (2) · Australia (1) · Brazil (1) · Canada (1) · Germany (1) · Italy (1) · Spain (1) · United Kingdom (1)
Thomas Adams, PhD (2) · Angus W MacDonald, PhD (1) · Benedict J Alter, MD, PhD (1) · Brian Berman, MD (1) · Brian Pinkston, MD, MPH (1) · Cheryl Lowry, MD, MPH (1) · Colleen Loo, MBBS (1) · Gopalkumar Rakesh, PhD (1) · Joshua E Mervis, BA (1) · Kevin Caulfield, PhD (1) · Larissa Albantakis, PhD (1) · Marcus Kaiser, PhD (1) · Marcus Meinzer, Prof., PhD (1) · Patricia B Mills, MD FRCPC (1)
PMID 34464485, PMID 35120184, PMID 37066217, PMID 40574976, PMID 40735279, PMID 41015289
K23MH111977 (2), R44AG077965 (1), RF1MH117032 (1), UL1TR002541 (1)