10 terminated. 10 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Terminated 10 |
| Phase 2 | 1 | Terminated 1 |
Follow Tranexamic Acid: new trials by email Literature Review of Tranexamic Acid trials Research Report on Tranexamic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure Tranexamic Acid, 0.9% sodium chloride - Cancer of the Bone, Limb Salvage | Phase 3 | Terminated | St. Jude Children's Research Hospital | 15 | 2021-01-29 | 2024-12-20 |
| DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery Tranexamic Acid - Bleeding, Surgical Blood Loss | Phase 3 | Terminated | Population Health Research Institute | 3242 | 2019-09-17 | 2026-10-26 |
| Minimize Menorrhagia in Women With Von Willebrand Disease recombinant von Willebrand factor, tranexamic acid - Von Willebrand Diseases | Phase 3 | Terminated | Margaret Ragni | 39 | 2019-02-07 | 2024-07-01 |
| Efficacy and Safety of Tranexamic Acid in Spinal Fusion Surgery Sodium Chloride 0.9% Inj, Tranexamic Acid - Spinal Fusion | Phase 3 | Terminated | Exela Pharma Sciences, LLC. | 5 | 2018-10-17 | 2021-06-21 |
| Tocilizumab (RoActemra) and Tranexamic Acid (Cyklokapron) Used as Adjuncts to Chronic Subdural Hematoma Surgery Tranexamic acid and Tocilizumab - Chronic Subdural Hematoma | Phase 2 / Phase 3 | Terminated | Oslo University Hospital | 382 | 2017-11-28 | 2021-10-13 |
| Preoperative Hexakapron Reduces Bleeding in Bariatric Surgery tranexamic acid, Placebo - Intra-Operative Injury - Other, Post Operative Hemorrhage | Phase 3 | Terminated | Sheba Medical Center | 152 | 2017-09-01 | 2023-04-19 |
| HiFIT Study : Hip Fracture: Iron and Tranexamic Acid Iron Isomaltoside 1000, Tranexamic Acid, Placebos iron isomaltoside 1000 - Hip Fractures Pathologic, Anemia | Phase 3 | Terminated | University Hospital, Angers | 419 | 2017-03-31 | 2022-08-02 |
| Topical Application of Tranexamic Acid and Postoperative Blood Loss in Femoral Neck Fractures Tranexamic Acid, placebo - Femoral Neck Fracture | Phase 3 | Terminated | Dr. Jeff Yach | 15 | 2013-04-01 | 2018-11-30 |
| Postoperative Bleeding Prevention in Massive Bone Tumour Resection Tranexamic Acid, Fibrin glue, Electrocauterization - Blood Loss, Bone Tumour | Phase 3 | Terminated | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 56 | 2013-03-01 | 2016-09-20 |
| Tranexamic Acid Versus Placebo to Reduce Perioperative Bleeding After Major Hepatectomy acid tranexamic, Nacl 0.9% - Blood Loss, Surgical | Phase 3 | Terminated | University Hospital, Strasbourg, France | 130 | 2008-08-20 | 2021-03-01 |
Blood Loss, Surgical (2) · Bone Neoplasms (2) · Hemorrhage (2) · Anemia (1) · Femoral Neck Fractures (1) · Fractures, Bone (1) · Hematoma, Subdural, Chronic (1) · Menorrhagia (1) · Obesity, Morbid (1) · Postoperative Hemorrhage (1) · Seizures (1) · von Willebrand Diseases (1)
Dr. Jeff Yach (1) · Exela Pharma Sciences, LLC. (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Margaret Ragni (1) · Oslo University Hospital (1) · Population Health Research Institute (1) · Sheba Medical Center (1) · St. Jude Children's Research Hospital (1) · University Hospital, Angers (1) · University Hospital, Strasbourg, France (1)
United States (3) · Canada (2) · France (2) · China (1) · Czechia (1) · Israel (1) · Malaysia (1) · New Zealand (1) · Norway (1) · Russia (1) · Spain (1)
Andre Lamy, MD (1) · Jeff Yach, MD (1) · Margaret V Ragni, MD, MPH (1) · Michael D. Neel, MD (1) · Milo Stanisic (1) · Neel Anand, MD (1) · Patrick Pessaux (1) · Sigismond SL Lasocki, PU-PH (1)
PMID 18480196, PMID 22054656, PMID 27774838, PMID 30146969, PMID 30908754, PMID 33455926, PMID 33781988, PMID 37385272, PMID 37524101, PMID 38587333, PMID 38689774, PMID 42423601
2017 (1), U01HL133815 (1)