9 completed, 6 terminated, 2 active not recruiting, 1 not yet recruiting. 15 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 7, Terminated 5, Active not recruiting 2, Not yet recruiting 1 |
| Phase 4 | 1 | Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TearCare in Young Adults TearCare® - Meibomian Gland Dysfunction (Disorder) | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 45 | 2026-08-01 | 2026-05-11 |
| TearCare MGX™ System With and Without Warming Hold localized heat therapy - Meibomian Gland Dysfunction (Disorder) | Not applicable | Completed | Sight Sciences, Inc. | 21 | 2026-03-17 | 2026-06-05 |
| OMNI 3.1 Surgical System in Subjects With Primary Open-Angle Glaucoma OMNI 3.0 Surgical System - Primary Open Angle Glaucoma | Not applicable | Active not recruiting | Sight Sciences, Inc. | 25 | 2025-10-08 | 2026-10-19 |
| A Study of the Helix Surgical System in Primary Open-Angle Glaucoma (POAG) and Cataract (HELIX) Helix Surgical System - Primary Open Angle Glaucoma, Cataract | Not applicable | Active not recruiting | Sight Sciences, Inc. | 25 | 2025-05-21 | 2026-07-07 |
| A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Patients With Primary Open Angle Glaucoma OMNI Surgical System, Latanoprost plus adjunctive glaucoma medication - Primary Open Angle Glaucoma | Phase 4 | Terminated | Sight Sciences, Inc. | 2 | 2024-08-21 | 2025-01-29 |
| Study of OMNI Surgical System and iStent for Eyes With OAG (Trident) Canaloplasty and trabeculotomy with the OMNI system., iStent inject, Canaloplasty - Glaucoma, Open-Angle | Not applicable | Terminated | Sight Sciences, Inc. | 10 | 2022-01-11 | 2025-10-27 |
| A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System OMNI® Surgical System - Glaucoma, Open-Angle | Completed | Sight Sciences, Inc. | 70 | 2021-09-01 | 2025-01-22 | |
| An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0) OMNI® Surgical System - Glaucoma, Open-Angle | Completed | Sight Sciences, Inc. | 28 | 2021-07-01 | 2025-05-22 | |
| Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA) TearCare System, Cyclosporine Ophthalmic 0.05% Ophthalmic Emulsion - Dry Eye, Meibomian Gland Dysfunction | Not applicable | Completed | Sight Sciences, Inc. | 345 | 2021-04-28 | 2025-11-24 |
| A Post-market Study Of Use Of The OMNI® Surgical System In Open Angle Glaucoma OMNI® Surgical System, iStent inject - Glaucoma, Open-Angle | Not applicable | Terminated | Sight Sciences, Inc. | 1 | 2020-11-13 | 2022-12-01 |
| A Prospective, Multicenter Study of the OMNI® Surgical System in Pseudophakic Eyes With Open Angle Glaucoma OMNI® Surgical System - Glaucoma, Open-Angle | Not applicable | Terminated | Sight Sciences, Inc. | 78 | 2020-06-19 | 2022-06-28 |
| Study of OMNI System in OAG (GEMINI) Transluminal viscoelastic delivery and trabeculotomy - Open Angle Glaucoma | Not applicable | Completed | Sight Sciences, Inc. | 209 | 2019-03-11 | 2024-08-14 |
| TearCare System to Treat Dry Eye Disease TearCare, LipiFlow - Dry Eye, Meibomian Gland Dysfunction | Not applicable | Completed | Sight Sciences, Inc. | 235 | 2019-03-03 | 2025-10-01 |
| Pilot Study of TearCare System - Long-Term Extension TearCare - Dry Eye Syndromes | Not applicable | Completed | Sight Sciences, Inc. | 12 | 2018-12-17 | 2025-10-28 |
| Study of the TearCare System in Dry Eye Disease TearCare - Dry Eye | Not applicable | Completed | Sight Sciences, Inc. | 29 | 2018-07-12 | 2025-09-11 |
| Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye Disease TearCare, Warm Compress and Lid Massage - Dry Eye Syndromes | Not applicable | Terminated | Sight Sciences, Inc. | 14 | 2018-04-20 | 2025-09-29 |
| Safety and Effectiveness of the Sight Sciences VISCO™360 Versus SLT in Primary Open Angle Glaucoma VISCO360 ab interno canaloplasty surgery, Selective Laser Trabeculoplasty (SLT) - Open-Angle Glaucoma | Not applicable | Terminated | Sight Sciences, Inc. | 29 | 2017-01-23 | 2025-11-14 |
| A Pilot Study of the TearCare System in Adults With Dry Eye Disease TearCare, Warm Compress - Dry Eye | Not applicable | Completed | Sight Sciences, Inc. | 24 | 2017-01-01 | 2025-10-15 |
Glaucoma, Open-Angle (10) · Dry Eye Syndromes (7) · Meibomian Gland Dysfunction (4) · Cataract (1)
Trabeculectomy (2) · Cyclosporins (1) · Latanoprost (1)
United States (15) · Panama (2) · Germany (1) · Spain (1) · United Kingdom (1)
Jaime Dickerson, PhD (7) · David Badawi, MD (2) · Anne-Marie Ripley (1) · Jaime C Dickerson, PhD (1) · Jillian F Ziemanski, OD, PhD, FAAO (1) · Kavita Dhamdhere, MD, PhD (1) · Thomas Chester, OD (1)