13 completed, 1 active not recruiting. 6 Phase 3, 4 Phase 2, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 5, Active not recruiting 1 |
| Phase 2 | 4 | Completed 4 |
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Tiagabine: new trials by email Literature Review of Tiagabine trials Research Report on Tiagabine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Population Pharmacokinetics of Antiepileptic in Pediatrics Valproic acid, carbamazepine, phenobarbital - Epilepsy | Completed | Assistance Publique - Hôpitaux de Paris | 753 | 2017-06-19 | 2025-11-20 | |
| Tiagabine to Enhance Slow Wave Sleep in Patients With Sleep Apnea Tiagabine, Placebo - Sleep Apnea, Obstructive | Phase 2 | Completed | Brigham and Women's Hospital | 18 | 2015-03-01 | 2017-08-15 |
| Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alcohol Dependence [11C]flumazenil, Tiagabine - Alcoholism | Phase 1 | Completed | Rajesh Narendran | 11 | 2011-04-19 | 2017-08-29 |
| A Prospective, Observational Study On The Effectiveness Of New Antiepileptic Drugs As First Bitherapy In The Daily Clinical Practice Gabapentin, Lamotrigine, Levetiracetam, Pregabalin, Oxcarbacepine, Tiagabine, Topiramate, Zonisamide - Focal Epilepsy | Phase 4 | Completed | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 111 | 2007-05-01 | 2021-01-25 |
| Study to Evaluate the Safety and Efficacy of GABITRIL Treatment in Adults With Generalized Anxiety Disorder. Gabitril - Anxiety Disorders | Phase 3 | Completed | Cephalon | 2005-01-01 | 2014-05-09 | |
| Effectiveness of Tiagabine for Cocaine Dependence in Methadone-Maintained Individuals - 1 Tiagabine - Cocaine-Related Disorders, Opiate Dependence | Phase 2 | Completed | National Institute on Drug Abuse (NIDA) | 80 | 2004-12-01 | 2017-01-12 |
| A 10-Week Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder Gabitril - Anxiety Disorder | Phase 3 | Completed | Cephalon | 880 | 2004-11-01 | 2014-05-09 |
| A 10-Week Study for Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder Gabitril - Generalized Anxiety Disorder | Phase 3 | Completed | Cephalon | 440 | 2004-10-01 | 2014-05-09 |
| A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder Gabitril - Generalized Anxiety Disorder | Phase 3 | Completed | Cephalon | 440 | 2004-10-01 | 2014-05-09 |
| Treating Schizophrenia by Correcting Abnormal Brain Development Tiagabine, Placebo - Schizophrenia | Phase 3 | Active not recruiting | Beth Israel Deaconess Medical Center | 36 | 2003-11-01 | 2025-01-27 |
| Evaluate the Safety of GABITRIL in Adults With Generalized Anxiety Disorder GABITRIL (tiagabine hydrochloride; CEP-6671) - General Anxiety Disorder | Phase 3 | Completed | Cephalon | 2003-08-01 | 2023-04-12 | |
| Tiagabine for the Treatment of Cocaine Dependence - 1 Tiagabine - Cocaine-Related Disorders | Phase 2 | Completed | National Institute on Drug Abuse (NIDA) | 140 | 2002-10-01 | 2017-01-12 |
| Study To Evaluate The Effects Of Gabitril™ In Patients With Social Anxiety Disorder Gabitril - Social Anxiety Disorder | Phase 4 | Completed | Emory University | 50 | 2002-06-01 | 2013-11-11 |
| Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine GABA Agonists - Cocaine-Related Disorders | Phase 2 | Completed | National Institute on Drug Abuse (NIDA) | 78 | 2001-08-01 | 2017-01-11 |
Cocaine-Related Disorders (3) · Generalized Anxiety Disorder (3) · Anxiety Disorders (2) · Alcoholism (1) · Epilepsies, Partial (1) · Epilepsy (1) · Opioid-Related Disorders (1) · Phobia, Social (1) · Psychological Well-Being (1) · Schizophrenia (1) · Sleep Apnea, Obstructive (1)
Cephalon (5) · National Institute on Drug Abuse (NIDA) (3) · Assistance Publique - Hôpitaux de Paris (1) · Beth Israel Deaconess Medical Center (1) · Brigham and Women's Hospital (1) · Emory University (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1) · Rajesh Narendran (1)
United States (11) · Canada (2) · France (1)
Charles Brown, MD (1) · Craig Rush (1) · Eugene Somoza, M.D., Ph.D. (1) · Gerardo Gonzalez, M.D. (1) · Philip T Ninan, MD (1) · Rajesh Narendran, MD (1)