51 completed, 44 recruiting, 38 not yet recruiting, 15 active not recruiting. 94 Not applicable, 40 Phase 2, 27 Phase 3, 13 Phase 4, 9 Phase 1.
Follow Standard of care (SOC): new trials by email Literature Review of Standard of care (SOC) trials Research Report on Standard of care (SOC)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Observe the Pattern of Use and Safety of Rivaroxaban in Children Under 2 Years Old With Venous Thromboembolism (VTE) Rivaroxaban (Xarelto, BAY59-7939), Standard of care (SOC) - Venous Thromboembolism, Children Under 2 Years | Not yet recruiting | Bayer | 850 | 2027-09-01 | 2026-10-02 | |
| Appendectomy as an Adjunct Procedure in Endometriosis Surgery Appendectomy, Standard of Care (SOC) - Endometriosis | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 240 | 2027-04-01 | 2026-09-16 |
| PRECISE LBCL: Precision Treatment Readiness Through Comprehensive Genomic Sequencing in 1st Line LBCL Standard of Care (SOC) - LBCL, Comprehensive Genomic | Not yet recruiting | M.D. Anderson Cancer Center | 60 | 2027-02-25 | 2026-09-21 | |
| Precision Modulation of Gut Microbiome Enteropathogen Colonization in Critical Illness Synbiotic, Standard of Care (SOC) - Critical Illness | Phase 1 / Phase 2 | Not yet recruiting | University of Calgary | 64 | 2027-01-01 | 2026-09-10 |
| A Randomized Controlled Trial of Doxycycline Post Exposure Prophylaxis to Prevent Incident Bacterial STIs Among Women in the United States Doxycycline, Standard of Care (SOC) - Chlamydia Females, Gonorrhea Female | Phase 4 | Not yet recruiting | Tulane University | 519 | 2027-01-01 | 2026-07-15 |
| "Anticipant"-TIPS After a First Portal-hypertension-related Complication in Cirrhosis TIPS, Standard of Care (SOC) - Cirrhosis | Not applicable | Not yet recruiting | University Hospital, Toulouse | 266 | 2027-01-01 | 2026-10-22 |
| Prospective Study of ProteiOS in Lumbar Interbody Fusion (TLIF) Allograft-derived growth factor (ProteiOS®), Standard of Care (SOC) - Degenerative Disc Disease, Spinal Stenosis Lumbar | Not applicable | Not yet recruiting | Isto Biologics | 280 | 2026-12-01 | 2026-08-20 |
| The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients Standard of Care (SOC) - Burn Degree Second, Burn Degree Third | Not yet recruiting | University Children's Hospital, Zurich | 236 | 2026-12-01 | 2026-05-26 | |
| DETECTRA: Remote Monitoring to Detect Rheumatoid Arthritis Flares and Treatment Response DETECTRA, Standard of Care (SOC) - Rheumatic Disorder, Rheumatoid Arthritis (RA) | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 320 | 2026-11-30 | 2026-10-05 |
| NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy Psilocybin (drug), Standard of Care (SOC) - Psilocybin, Neuropathy | Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 83 | 2026-11-04 | 2026-10-05 |
| SALI-10 Probiotic to Reduce Osteoradionecrosis and Dental Toxicity Following Radiation Therapy for Head and Neck Cancer Standard of Care (SOC), Experimental drug - Head and Neck Cancer | Phase 3 | Not yet recruiting | University Health Network, Toronto | 288 | 2026-11-01 | 2026-10-20 |
| Creating Opportunities For Personal Empowerment (COPE) In Women With Breast Cancer During First-Line Therapy: A Pilot Randomized Controlled Trial Standard of Care (SOC), Intervention sessions - COPE, Breast Cancer | Not applicable | Not yet recruiting | M.D. Anderson Cancer Center | 40 | 2026-10-30 | 2026-05-28 |
| Primary Radiotherapy In MEtastatic Lung Cancer Radiotherapy followed by chemotherapy, Standard of Care (SOC) - Carcinoma, Non-Small-Cell Lung (NSCLC) | Phase 3 | Recruiting | Trans Tasman Radiation Oncology Group | 420 | 2026-10-30 | 2026-10-14 |
| Ensifentrine (MK-5884) Study for the Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations in Adults With a History of Moderate or Severe Exacerbations While Receiving Standard of Care (SOC) (MK-5884-031/RPL554/ENHANCE-3) Ensifentrine, Placebo, Standard of Care (SOC) - Pulmonary Disease, Chronic Obstructive | Phase 3 | Not yet recruiting | Merck Sharp & Dohme LLC | 2136 | 2026-10-23 | 2026-10-15 |
| CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock Methylprednisone, Standard of Care (SOC) - Cardiogenic Shock, Heart Failure | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 30 | 2026-10-01 | 2026-08-13 |
| Community Support and Mobile Apps to Help Black Women Control High Blood Pressure After Pregnancy Collaborative care, Standard of Care (SOC) - Hypertensive Disorders of Pregnancy (HDP), Hypertension, Pregnancy Induced | Not applicable | Not yet recruiting | University of Nebraska | 404 | 2026-10-01 | 2026-09-22 |
| Efficacy of Oral Nutritional Supplement in Community-Dwelling Adults Following Acute Care ONS, Standard of Care (SOC) - Low Muscle Strength, Malnutrition | Not applicable | Not yet recruiting | Abbott Nutrition | 304 | 2026-10-01 | 2026-08-07 |
| Evaluation of Safety and Efficacy of Dehydrated Human Amnion-Intermediate-Chorion Membrane (dHAICM) Allograft in Treatment of Partial Thickness Thermal Burns Amnion-Intermediate-Chorion, Standard of Care (SOC) - Partial Thickness Burn | Phase 4 | Withdrawn | Cellution Biologics | 2026-10-01 | 2026-08-27 | |
| A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections Amicidin-β topical solution - 15 mL, Amicidin-β topical solution - 50 mL, Standard of Care (SOC) - Surgical Wound Infection, Traumatic Wound Infection | Phase 1 | Recruiting | Macro Biologics, Inc. | 44 | 2026-09-30 | 2026-08-17 |
| Pix-Risk: Early Detection of Rheumatoid Arthritis Via the DETECTRA Platform DETECTRA, Standard of Care (SOC) - Rheumatoid Arthritis (RA | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 142 | 2026-09-28 | 2026-09-17 |
Showing 20 of 178. Sign in to see all of them.
COVID-19 (14) · Diabetic Foot (10) · Diabetes Mellitus (5) · Acute Kidney Injury (4) · Sepsis (4) · Surgical Wound Infection (4) · Varicose Ulcer (4) · Acquired Immunodeficiency Syndrome (3) · Anxiety Disorders (3) · Depression (3) · Diabetes Mellitus, Type 2 (3) · Fibrosis (3) · Foot Ulcer (3) · HIV Infections (3) · Head and Neck Neoplasms (3)
Novartis Pharmaceuticals (7) · Assistance Publique - Hôpitaux de Paris (5) · Emory University (5) · Cellution Biologics (4) · M.D. Anderson Cancer Center (4) · PolyPid Ltd. (3) · Abbott Nutrition (2) · Bayer (2) · CardioRenal Systems, Inc. (2) · Centre Hospitalier Universitaire Vaudois (2) · EMD Serono Research & Development Institute, Inc. (2) · Ethicon, Inc. (2) · Irrimax Corporation (2) · Janssen Research & Development, LLC (2) · Johns Hopkins University (2)
United States (89) · Germany (23) · Italy (16) · Spain (16) · France (15) · Australia (12) · Poland (12) · United Kingdom (12) · Canada (11) · Israel (11) · Czechia (8) · Switzerland (8) · Denmark (7) · Netherlands (7) · Romania (7)
Shmuel Sharoni, MD (2) · Aditya H Gaur, MD (1) · Alan Barber, PhD (1) · Alex Hall, DHSc (1) · Alexandra I Halalau, MD (1) · Alexandra Papaioannou, Professor of Anaesthesiology (1) · Allison Matthews (1) · Amy Rothberg, MD (1) · Ana Rita Londral, PhD (1)
PMID 12148093, PMID 20543206, PMID 21701326, PMID 22449295, PMID 25057935, PMID 25058504, PMID 25304302, PMID 26197368, PMID 26636489, PMID 26936623, PMID 27017161, PMID 28202770, PMID 28223475, PMID 28455343, PMID 28487318, PMID 29712625, PMID 30143033, PMID 30304509, PMID 30448118, PMID 30832717, PMID 32270297, PMID 32345658, PMID 32779730, PMID 33225960, PMID 33502773, PMID 33504262, PMID 33960843, PMID 33966447, PMID 34001215, PMID 34050768, PMID 34473343, PMID 34855613, PMID 34886993, PMID 35244208, PMID 35296307, PMID 35776441, PMID 35995638, PMID 36104613, PMID 36328157, PMID 36730762, PMID 37081534, PMID 37154020, PMID 37237315, PMID 37338154, PMID 37348035, PMID 37591523, PMID 37715999, PMID 38099161, PMID 38828958, PMID 39139188
2017 (4), 2025 (4), 2018 (1), 2023 (1), 5UG1MD019436-02 (1), K23MH114632 (1), K23MH131463 (1), R01CA296402 (1), R01DA041032 (1), R01DK124862 (1), R01MD015818 (1), R21AG077092 (1), R21AG083667 (1), R21AR082111 (1), R33HD110150 (1)