19 completed, 9 not yet recruiting, 8 unknown, 7 recruiting. 24 Not applicable, 11 Phase 3, 9 Phase 2, 9 Phase 4.
Follow Standard Medical Therapy: new trials by email Literature Review of Standard Medical Therapy trials Research Report on Standard Medical Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Very Low-volume Plasma Exchange in ACLF Double Plasma Molecular Adsorption System (DPMAS), Low-volume plasma exchange, Prothrombin Complex Concentrate (PCC) - Acute on Chronic Liver Failure (ACLF) | Not applicable | Not yet recruiting | Third Affiliated Hospital, Sun Yat-Sen University | 840 | 2026-10-01 | 2026-10-05 |
| Safety and Efficacy of Carotid Artery Stenting Combined With Intermittent Hypoxia Intervention in Patients With Severe Internal Carotid Artery Stenosis intermittent hypoxia intervention, Carotid Artery Stenting (CAS), Standard Medical Therapy - Internal Carotid Artery Stenosis | Not applicable | Not yet recruiting | Capital Medical University | 176 | 2026-09-20 | 2026-09-25 |
| Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease Secukinumab (75 mg), Standard Medical Therapy - Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease | Phase 4 | Not yet recruiting | Peking University Third Hospital | 100 | 2026-07-15 | 2026-07-15 |
| Outcome of Clinical Phenotypes of Pediatric Myocarditis at Assiut University Children Hospital Standard Medical Therapy - Myocarditis, Myocarditis Acute | Not yet recruiting | Assiut University | 100 | 2026-06-01 | 2025-09-16 | |
| Acupuncture for Preventing Atrial Arrhythmia Recurrence After Ablation Electroacupuncture, Standard Medical Therapy - Atrial Fibrillation (AF) | Not applicable | Not yet recruiting | Shanghai Zhongshan Hospital | 120 | 2026-04-01 | 2026-04-01 |
| Eptifibatide for Extended Window Ischemic Stroke After Thrombolysis Eptifibatide (Integrilin), Standard Medical Therapy - Acute Ischemic Stroke | Phase 3 | Not yet recruiting | Xinqiao Hospital of Chongqing | 786 | 2026-03-01 | 2026-01-16 |
| Identifying Risk Factors and Predicting Future Health Outcomes for Korean Patients With Heart and Blood Vessel Diseases: A Long-term Follow-up Study Standard Medical Therapy, Revascularization Procedures, Lifestyle Modification - Cardiovascular Diseases (CVD), Cerebro Vascular Disease | Recruiting | Samsung Medical Center | 800000 | 2026-02-02 | 2026-04-28 | |
| Intravenous Tirofiban After Bridging Therapy for Acute Stroke With Atherosclerotic Large Artery Occlusion Intravenous Tirofiban, Standard Medical Therapy - Acute Ischemic Stroke | Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 564 | 2026-01-12 | 2026-01-13 |
| KD Treatment for Super-refractory Status Epilepticus the ketogenic diet, Standard Medical Therapy - Super-refractory Status Epilepticus | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 84 | 2025-10-20 | 2026-05-15 |
| Efficacy, Safety, and ToLerability of Switching to A Two-Drug Regimen With DTG/3TC Compared to Maintaining A Three-Drug REgimen With BIC/FTC/TAF or DTG/3TC/ABC in ViroLogically SupprEssed PeopLe Living With HIV After 24 and 48 Weeks of Follow-Up Standard Medical Therapy, dual therapy - HIV Infections | Phase 4 | Recruiting | José Antonio Mata Marín | 156 | 2025-07-12 | 2025-08-22 |
| Standard-of-care Systemic Therapy With or Without Local Therapy in Patients With Oligoprogressive Non-Small Cell Lung Cancer(NSCLC) Radiotherapy or Surgery, Standard Medical Therapy - OligoProgressive Metastatic Disease, Non-Small Cell Lung Cancer | Phase 2 / Phase 3 | Active not recruiting | Shanghai Chest Hospital | 97 | 2025-06-03 | 2025-07-22 |
| Standardized Antihypertensive Treatment Protocol Usual Care, Standard Medical Therapy - Hypertension | Not applicable | Not yet recruiting | Shanghai Jiao Tong University School of Medicine | 400 | 2025-02-24 | 2025-01-24 |
| Systemic Antitumor Treatment with or Without Pressurized Intraperitoneal Aerosol Chemotherapy for Colon Peritoneal Metastases (PIPOX02) Standard Medical Therapy, PIPAC - Peritoneal Metastases from Colorectal Cancer | Phase 2 | Not yet recruiting | Institut Cancerologie de l'Ouest | 114 | 2025-02-01 | 2024-11-08 |
| Remote Cardiovascular Monitoring in Post-TAVI Patients Remote Patient Monitoring Strategy, Standard Medical Therapy - Aortic Valve Stenosis, Cardiac Conduction Disturbance | Not applicable | Recruiting | Imperial College London | 216 | 2024-11-01 | 2026-03-03 |
| Combination of TURP and Standard Systemic Therapy for MPCa TURP, Standard Medical Therapy - Metastatic Prostate Cancer | Phase 2 | Recruiting | Fudan University | 200 | 2024-09-21 | 2024-10-23 |
| RCT of Gut-directed Hypnotherapy in Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders Gut-directed hypnotherapy, Standard Medical Therapy - Ehlers-Danlos Syndrome, Irritable Bowel Syndrome | Not applicable | Unknown | University Health Network, Toronto | 74 | 2024-04-01 | 2024-03-22 |
| Extracorporal Cytokin Removal in Septic Shock: a Prospective, Randomized, Multicenter Clinical Trial Standard medical therapy, Standard medical therapy plus cytokine removal treatment using Cytosorb, with the adsorber changed in every 12 hours, Standard medical therapy plus cytokine removal treatment using Cytosorb, with the adsorber changed in every 24 hours - Septic Shock | Phase 3 | Suspended | University of Pecs | 135 | 2024-01-01 | 2023-04-20 |
| Role of Extended Low Dose Prednisolone in Achieving Clinical and Biochemical Remission in Steroid Responsive Severe Alcoholic Hepatitis Prednisolone, Standard Medical therapy, Placebo - Severe Alcoholic Hepatitis | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 150 | 2023-11-25 | 2023-12-04 |
| Effectiveness and Safety of Darunavir/Cobicistat Plus Lamivudine Versus Darunavir/Cobicistat Plus Tenofovir/Emtricitabine in Virologically Suppressed HIV-1-positive Individuals in Mexico dual therapy, Standard Medical Therapy - HIV Infection | Phase 4 | Recruiting | José Antonio Mata Marín | 138 | 2023-11-09 | 2025-04-04 |
| Prevalence of Humoral Dysfunction in Pts With Frequent Exacerbations of COPD, and the Effect of SCIgR for Prevention CUVITRU - Ig subcutaneous human 20%, Standard Medical Therapy - COPD Exacerbation Acute | Phase 2 | Unknown | Rochester General Hospital | 40 | 2023-06-01 | 2023-06-15 |
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Heart Failure (5) · Fibrosis (4) · Liver Cirrhosis (4) · Liver Failure (4) · Coronary Artery Disease (3) · Hepatitis, Alcoholic (3) · Ischemic Stroke (3) · Acute-On-Chronic Liver Failure (2) · Ascites (2) · Atrial Fibrillation (2) · Carcinoma, Non-Small-Cell Lung (2) · Cardiomyopathy, Dilated (2) · Cardiovascular Diseases (2) · Carotid Stenosis (2) · HIV Infections (2)
Post Graduate Institute of Medical Education and Research, Chandigarh (6) · Institute of Liver and Biliary Sciences, India (3) · Campus Bio-Medico University (2) · Hepa Wash GmbH (2) · José Antonio Mata Marín (2) · LoneStar Heart, Inc. (2) · Vantive Health LLC (2) · Albert Einstein Healthcare Network (1) · Assiut University (1) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Beijing Tiantan Hospital (1) · Capital Medical University (1) · Cheng-Hsin General Hospital (1) · Fudan University (1) · Hunter Holmes Mcguire Veteran Affairs Medical Center (1)
China (10) · India (9) · Italy (6) · Germany (5) · United States (5) · France (3) · United Kingdom (3) · Belgium (2) · Canada (2) · Denmark (2) · Mexico (2) · Romania (2) · Taiwan (2) · Australia (1) · Austria (1)
Wolfgang Huber, PD Dr. (2) · Anthony Tang, MD FRCPC (1) · Carlo Ferrarese, MD, PhD (1) · Cristian Oancea, University Professor, MD, PhD (1) · Daojun Hong, MD (1) · Denise Lester, MD (1) · Emilio Bria, PhD (1) · Fabio Mangiacapra, MD, PhD (1) · George Wells, PhD (1) · Louis Liu (1) · Maurizio V Infante (1) · Maurizio Volterani, MD (1) · Michele Milella, PhD (1)
PMID 28209134, PMID 37035316, PMID 16053957, PMID 16609953, PMID 16715053, PMID 17882162, PMID 17975845, PMID 18160685, PMID 22516442, PMID 23463755, PMID 24203849, PMID 24415559, PMID 24643082, PMID 26082085, PMID 26555602, PMID 26699389, PMID 26898852, PMID 27149033, PMID 27412192, PMID 27520989, PMID 27614145, PMID 28052979, PMID 28265014, PMID 28361616, PMID 28847867, PMID 29127270, PMID 29129157, PMID 29278428, PMID 29364767, PMID 29391265, PMID 29503556, PMID 29766770, PMID 30838514, PMID 30850001, PMID 31004141, PMID 31067369, PMID 31570084, PMID 31662037, PMID 31698933, PMID 31831388, PMID 31902242, PMID 3201508, PMID 32088302, PMID 32731250, PMID 33176455, PMID 33296224, PMID 33427887, PMID 33462764, PMID 33793319, PMID 34329730
2017 (1)