13 completed, 1 recruiting, 1 terminated, 1 unknown. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 13, Recruiting 1, Terminated 1, Unknown 1 |
Follow Simethicone: new trials by email Literature Review of Simethicone trials Research Report on Simethicone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Simethicone as Part of ERAS in Bariatric Surgery Patients Simethicone 80 MG, Placebo - Simethicone, Bariatric Surgery | Phase 4 | Recruiting | Madigan Army Medical Center | 260 | 2025-04-08 | 2025-06-15 |
| Exploratory Pilot Study to Evaluate the Pharmacokinetic Profile of Magaldrate Sodium alginate + sodium bicarbonate + magaldrate + simeticone - Healthy | Phase 4 | Completed | Tecnoquimicas | 10 | 2023-10-31 | 2024-04-16 |
| Low-volume vs High-volume Polyethylene Glycol Based Bowel Preparation for Colonoscopy in People Receiving Hemodialysis 2-liters polyethylene glycol with citrate and simethicone, 4-liters polyethylene glycol with simethicone, Low-residue diet - Chronic Kidney Diseases, Colon Polyp | Phase 4 | Unknown | Alfredo Di Leo | 264 | 2021-02-01 | 2021-01-14 |
| Combination of Alverine-simeticone and i3.1 Probiotic in IBS-D and IBS-M in Mexico I31 probiotic, I31 probiotic combined to Alverine/Simethicone, Placebo - Irritable Bowel Syndrome | Phase 4 | Completed | Hospital Juarez de Mexico | 55 | 2018-09-03 | 2020-01-23 |
| Simethicone and Bowel Preparation in Colonoscopy Simethicone 180Mg Cap - Colonoscopy, Bowel Preparation | Phase 4 | Completed | University of Manitoba | 471 | 2017-07-05 | 2018-05-23 |
| Effect of Simethicone on Screening Colonoscopy Simethicone Solution, Polyethylenglycol - Adenoma Colon | Phase 4 | Completed | Texas Tech University Health Sciences Center, El Paso | 268 | 2017-03-15 | 2019-06-05 |
| Simethicone and N-acetylcysteine in Upper Endoscopy - Prospective Double-blinded Randomized Controlled Trial Simethicone, Acetylcysteine, Placebo - Gastric Mucosal Lesion | Phase 4 | Completed | Portuguese Oncology Institute, Coimbra | 300 | 2015-04-01 | 2016-01-08 |
| Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery Simethicone, Oral Suspending Vehicle - Postoperative Ileus, Ileus | Phase 4 | Completed | McMaster University | 100 | 2014-10-01 | 2015-12-04 |
| Simethicone: Does it Improve Operative Field and Postoperative Pain? Simethicone Tab 40 mg, Placebo Tablets - Simethicone | Phase 4 | Completed | Woman's Health University Hospital, Egypt | 100 | 2014-08-01 | 2016-12-07 |
| Pilot Study to Assess Dimethyl Fumarate Related GI Symptom Mitigation Simethicone, Loperamide, Peanut Butter - Relapsing Remitting Multiple Sclerosis | Phase 4 | Terminated | Rocky Mountain MS Research Group, LLC | 5 | 2014-07-01 | 2017-03-23 |
| Efficacy of Matricariae Chamomilla L., Melissa Officinalis L. and Tyndallized Lactobacillus Acidophilus (H122) for Infantile Colics Standardized extract of Chamomilla L., Melissa Officinalis L. and tyndallized L. Acidophilus (H122), Lactobacillus reuteri DSM 17938 (108 CFU), Simethicone - Infantile Colics | Phase 4 | Completed | Federico II University | 180 | 2014-04-01 | 2016-07-29 |
| Premedication With Simethicone or Simethicone Plus N-acetylcysteine in Improving Visibility During Upper Endoscopy Water (Placebo), Simethicone, N-acetylcysteine 500 mg - Stomach Neoplasms | Phase 4 | Completed | Pontificia Universidad Catolica de Chile | 230 | 2012-07-01 | 2018-04-10 |
| Effectiveness of On-demand Meteospasmyl® Use in Irritable Bowel Syndrome (IBS) anti spasmodic agents, alverine citrate, simeticone - Irritable Bowel Syndrome | Phase 4 | Completed | Laboratoires Mayoly Spindler | 436 | 2009-12-01 | 2014-11-04 |
| A Comparison of Three Medications to Treat Diarrhea in Adults. Loperamide/simeticone 2 mg/125 mg caplets, Loperamide/simeticone 2 mg/125 mg chewable tablets, Probiotic Saccharomyces boulardii 250 mg capsules - Diarrhea | Phase 4 | Completed | McNeil AB | 415 | 2008-11-01 | 2012-07-10 |
| Efficacy and Safety of Meteospasmyl® in Irritable Bowel Syndrome alverine citrate and simeticone, placebo - Irritable Bowel Syndrome | Phase 4 | Completed | Laboratoires Mayoly Spindler | 400 | 2007-07-01 | 2008-10-01 |
| The Effectiveness of Simethicone In Improving Visibility During Colonoscopy Simethicone, Placebo - Colonoscopy | Phase 4 | Completed | Ramathibodi Hospital | 194 | 2006-12-01 | 2013-02-22 |
Irritable Bowel Syndrome (3) · Abdominal Pain (1) · Colonic Neoplasms (1) · Colonic Polyps (1) · Diarrhea (1) · Flatulence (1) · Ileus (1) · Multiple Sclerosis, Relapsing-Remitting (1) · Pain (1) · Pain, Postoperative (1) · Postoperative Complications (1) · Renal Insufficiency, Chronic (1) · Stomach Neoplasms (1)
Laboratoires Mayoly Spindler (2) · Alfredo Di Leo (1) · Federico II University (1) · Hospital Juarez de Mexico (1) · Madigan Army Medical Center (1) · McMaster University (1) · McNeil AB (1) · Pontificia Universidad Catolica de Chile (1) · Portuguese Oncology Institute, Coimbra (1) · Ramathibodi Hospital (1) · Rocky Mountain MS Research Group, LLC (1) · Tecnoquimicas (1) · Texas Tech University Health Sciences Center, El Paso (1) · University of Manitoba (1) · Woman's Health University Hospital, Egypt (1)
United States (3) · Canada (2) · Mexico (2) · Brazil (1) · Chile (1) · Hungary (1) · India (1) · Poland (1) · Portugal (1) · Thailand (1)
Abhasnee Sobhonslidsuk, M.D. (1) · Adolfo Parra-Blanco, MD (1) · Alfredo Di Leo, MD PhD (1) · Annamaria Staiano, Prof. (1) · Antonio H Mendoza-Ladd, MD (1) · Cagla Eskicioglu, MD, MSc (1) · Charlenn Skead, BA (1) · Elisabeth Kruse, PhD (1) · Esteban Glasinovic, MD (1) · Hugo Monrroy, MD (1) · John F Foley, MD (1) · Melissa Towle, RN (1) · Nuria Lopez Perez, MD (1) · Philippe Ducrotte, M.D (1)
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