5 completed, 4 unknown, 3 not yet recruiting, 2 enrolling by invitation. 10 Not applicable, 2 Phase 2, 2 Phase 4, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Unknown 4, Not yet recruiting 3, Enrolling by invitation 2, Recruiting 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Sham patch: new trials by email Literature Review of Sham patch trials Research Report on Sham patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty NEUROCUPLE™ Patch, Sham patch, Enhanced Recovery After Surgery (ERAS) Standard of Care - Total Knee Arthroplasty Postoperative Pain, Opioid Reduction After TKA | Not applicable | Not yet recruiting | Jacques E. Chelly | 274 | 2026-12-01 | 2026-07-06 |
| Efficacy of Traditional Chinese Medicine Patch Application at the Shenque (RN8) Acupoint in Cancer Patients Scheduled to Undergo Radiotherapy: A Study on Cancer-Related Fatigue and Heart Rate Variability Sham Patch, Traditional Chinese Medicine Patch - Cancer-related Fatigue | Not applicable | Not yet recruiting | China Medical University Hospital | 80 | 2026-08-01 | 2026-07-24 |
| NeuroCuple to Mitigate Post-Wisdom Teeth Extraction Opioid Risks NEUROCUPLE™ Patch, Sham Patch - Wisdom Teeth, Wisdom Teeth Extraction or Jaw Implant | Not applicable | Not yet recruiting | nCap Medical | 120 | 2026-06-30 | 2026-03-31 |
| A Study of the Jovi Patch, Powered by Signal Relief, for the Improvement of General Menstrual Discomfort Jovi Patch, Sham Patch - General Menstrual Discomfort | Not applicable | Recruiting | Signal Relief | 50 | 2026-05-08 | 2026-09-17 |
| Prevention and Reduction of Falls: Testing and Evaluating Cutting Edge Haptic Technology LIBERTY Patch, Sham Patch - Fall Risk, Fall Risk, Fall Prevention | Not applicable | Enrolling by invitation | SuperPatch Limited LLC | 150 | 2025-06-16 | 2026-08-24 |
| Evaluating Non-Invasive Haptics During Extreme Exercise Victory Patch with Haptic Vibrotactile Trigger Technology, Sham patch - VO2max, Lactate Threshold | Not applicable | Enrolling by invitation | SuperPatch Limited LLC | 75 | 2025-01-05 | 2026-08-20 |
| Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE) Buprenorphine Transdermal Matrix Patch, Sham patch - Opioid Use Disorder, Pregnancy Related | Phase 3 | Completed | Washington University School of Medicine | 7 | 2023-11-27 | 2026-09-10 |
| Efficacy of Transdermal Microneedle Patch for Topical Anesthesia Enhancement in Paediatric Thalassemia Patients Microneedle, 1 Finger Tip Unit (FTU) EMLA Cream (30-minute application time), 1 Finger Tip Unit (FTU) EMLA (15-minute application time) - Thalassemia in Children | Phase 2 | Completed | Universiti Kebangsaan Malaysia Medical Centre | 20 | 2021-09-15 | 2022-09-02 |
| nCap Pain Relief Patch vs. Placebo nCap pain relief patch, Sham Patch - Osteoarthritis, Knee | Not applicable | Unknown | nCap Medical | 70 | 2021-04-16 | 2021-04-20 |
| Transdermal Lidocaine for Pain Control During Diagnostic Office Hysteroscopy lidocaine patch, Sham patch - Infertility, Female | Not applicable | Unknown | Aswan University Hospital | 200 | 2020-09-01 | 2020-08-19 |
| Transdermal Lidocaine for Pain Control During Hysterosalpingography lidocaine patch, Sham patch - Infertility, Female | Not applicable | Unknown | Aswan University Hospital | 120 | 2020-09-01 | 2020-09-21 |
| Transdermal Lidocaine Administration Prior to Insertion Levonorgestrel-releasing Intrauterine System lidocaine patch, Sham patch - IUCD Complication | Not applicable | Unknown | Aswan University Hospital | 200 | 2020-09-01 | 2020-09-21 |
| Post-Op Lidocaine Patch Lidoderm 5 % Topical Patch, Sham Topical Patch - Pain, Postoperative | Phase 4 | Completed | Oregon Health and Science University | 50 | 2018-03-13 | 2020-03-11 |
| Acne Treatment With Active Patches Which Contains Azelaic Acid, Citric Acid,Salicylic Acid and 2% Ascorbic Acid OPLON active patch, Sham patch - Acne Vulgaris | Phase 1 / Phase 2 | Completed | Oplon-Pure Science Ltd. | 35 | 2010-03-01 | 2010-08-11 |
| Brain Imaging of Lidoderm for Chronic Back Pain lidocaine, placebo - Low Back Pain | Phase 4 | Completed | Northwestern University | 38 | 2004-01-01 | 2013-07-30 |
Infertility, Female (2) · Pain, Postoperative (2) · Acne Vulgaris (1) · Arthritis (1) · Low Back Pain (1) · Opioid-Related Disorders (1) · Osteoarthritis, Knee (1) · Pain (1) · Pregnancy Complications (1)
Aswan University Hospital (3) · SuperPatch Limited LLC (2) · nCap Medical (2) · China Medical University Hospital (1) · Jacques E. Chelly (1) · Northwestern University (1) · Oplon-Pure Science Ltd. (1) · Oregon Health and Science University (1) · Signal Relief (1) · Universiti Kebangsaan Malaysia Medical Centre (1) · Washington University School of Medicine (1)
United States (8) · Egypt (3) · Israel (1) · Malaysia (1) · United Kingdom (1)
Amy Monroe, MPH, MBA (1) · Apkar V. Apkarian, PhD (1) · Avner Shemer, MD (1) · Catherine Leclair, MD (1) · Daniel Hawkins, MD (1) · Jacques E. Chelly, MD, PhD, MBA (1) · Jeannie C Kelly, MD, MS (1) · Mark Sakr, DO (1)