284 completed, 109 unknown, 60 recruiting, 52 terminated. 591 Phase 3, 54 Phase 2.
Follow Radiotherapy: new trials by email Literature Review of Radiotherapy trials Research Report on Radiotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis Biopsy Procedure, Biospecimen Collection, Breast Conservation Treatment - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 562 | 2027-03-09 | 2026-10-13 |
| Assessment of Biosignature Classification of DCIS for RadioTherapy Benefit Post Lumpectomy (ABCD RT) Radiation Therapy, Standard of Care Radiation Therapy, No Intervention - Breast Cancer | Phase 3 | Not yet recruiting | NRG Oncology | 5270 | 2027-01-30 | 2026-09-30 |
| PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma Chemical Exchange Saturation Transfer Magnetic Resonance Imaging, Contrast-enhanced Magnetic Resonance Imaging, Magnetic Resonance Imaging - Glioblastoma | Phase 3 | Not yet recruiting | Jonsson Comprehensive Cancer Center | 60 | 2026-12-01 | 2026-07-07 |
| Sequential Chemotherapy Followed by Ultrahypofractionated Radiotherapy for Muscle-Invasive Bladder Cancer Transurethral Resection of Bladder Tumor, Sequential Systemic Chemotherapy, radiotherapy - Bladder Cancer, TURBT | Phase 3 | Not yet recruiting | Assiut University | 71 | 2026-12-01 | 2026-11-03 |
| Sintilimab Combined With LCCRT Followed by Capeox Chemotherapy in pMMR/MSS/MSI-L Locally Advanced Rectal Cancer Oxaliplatin, Placebo, radiotherapy - Locally Advanced Rectal Cancer | Phase 3 | Not yet recruiting | Innovent Biologics (Suzhou) Co. Ltd. | 500 | 2026-11-25 | 2026-11-04 |
| DEPART Study at Yale Radiation Therapy - Dupuytren's Contracture | Phase 3 | Not yet recruiting | Yale University | 158 | 2026-11-01 | 2026-10-13 |
| Best Salvage Treatment for High-risk Relapsing Prostate Cancer (PEACE-9 - ESCALATE-RT) Radiotherapy for MDT ± WPRT, Androgen Deprivation Therapy (ADT), Enzalutamide - Prostatic Neoplasms, Biochemical Recurrence | Phase 3 | Not yet recruiting | Ente Ospedaliero Cantonale, Bellinzona | 140 | 2026-11-01 | 2026-08-24 |
| Tris-CAR-T Cell Therapy Targeting CD44 and CD133 in Newly Diagnosed Glioblastoma Tris-CAR-T cell injection, Ommaya reservoir implantation, Temozolomide (TMZ) - Newly Diagnosed Glioblastoma, IDH-wildtype | Phase 2 / Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 60 | 2026-10-15 | 2026-10-14 |
| FAPI-Guided Radiotherapy With Cadonilimab and Standard Chemotherapy for Colorectal Peritoneal Metastasis: A Phase III Randomized Controlled Trial (TORHC-PM02) Second-Line Chemotherapy, Radiation Therapy, Cadonilimab (AK104) - Colon Rectal Cancer Adenocarcinoma, Peritoneal (Metastatic) Cancer | Phase 3 | Recruiting | Fudan University | 198 | 2026-10-01 | 2026-10-13 |
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | Children's Oncology Group | 1708 | 2026-08-28 | 2026-07-30 |
| Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old FOLFOX4s, Short Course Radiotherapy - Locally Advanced Rectal Adenocarcinoma | Phase 3 | Not yet recruiting | UNICANCER | 160 | 2026-07-24 | 2026-07-24 |
| Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging - Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma | Phase 3 | Recruiting | NRG Oncology | 398 | 2026-07-16 | 2026-09-10 |
| A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS) Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Rhabdomyosarcoma | Phase 3 | Recruiting | Children's Oncology Group | 342 | 2026-07-14 | 2026-08-25 |
| A Phase III, Randomized, Double-blind, Multi-center Trial Comparing Efficacy and Safety of Trilaciclib Versus Placebo in Participants With Limited-stage Small Cell Lung Cancer Trilaciclib, Trilaciclib Placebo, Etoposide Injection - Myelosuppression | Phase 3 | Active not recruiting | Jiangsu Simcere Pharmaceutical Co., Ltd. | 106 | 2026-06-17 | 2026-10-19 |
| Radiotherapy With GX Regimen as Adjuvant Therapy for High-risk Patients Following Pancreatic Cancer Surgery Radiotherapy + GX, GX group - Pancreatic Cancer | Phase 3 | Recruiting | Tianjin Medical University Cancer Institute and Hospital | 288 | 2026-05-22 | 2026-06-08 |
| Disitamab Vedotin Plus Radiotherapy for Adjuvant Treatment of HER2-Expressing Cisplatin-Ineligible Upper Tract Urothelial Carcinoma Disitamab Vedotin (RC48), radiotherapy, Gemcitabine (1000 mg/m2) - Upper Tract Urothelial Carcinoma | Phase 3 | Recruiting | Peking University First Hospital | 192 | 2026-05-01 | 2026-09-28 |
| Radiotherapy After Prostatectomy for Node Positive Prostate Cancer Androgen Deprivation Therapy (ADT), radiotherapy - Prostate Cancer (Post Prostatectomy), Radiotherapy; Image-Guided | Phase 3 | Recruiting | Sun Yat-sen University | 372 | 2026-03-20 | 2026-06-16 |
| Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma Bemcentinib, Nimotuzumab, radiotherapy - Head & Neck Squamous Cell Carcinoma, Head & Neck Cancer | Phase 3 | Recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 370 | 2026-03-04 | 2026-04-17 |
| Topical Periplaneta Americana-Derived Meilian Fuxin Liquid for Radiation Dermatitis Topical application of Periplaneta americana-derived Meilian Fuxin Solution, Topical application of placebo, Radiotherapy - Radiation-induced Dermatitis | Phase 2 / Phase 3 | Recruiting | West China Hospital | 60 | 2026-03-01 | 2026-03-25 |
| De-Escalation Surgery After Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma De-escalation surgery, Standard Surgery, radiotherapy - Squamous Cell Carcinoma of the Head and Neck | Phase 3 | Not yet recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 356 | 2026-01-01 | 2026-01-06 |
Showing 20 of 591. Sign in to see all of them.
Breast Neoplasms (60) · Prostatic Neoplasms (55) · Squamous Cell Carcinoma of Head and Neck (45) · Carcinoma, Non-Small-Cell Lung (42) · Head and Neck Neoplasms (40) · Lung Neoplasms (37) · Lymphoma (37) · Leukemia (27) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (24) · Esophageal Squamous Cell Carcinoma (22) · Brain Neoplasms (21) · Central Nervous System Neoplasms (20) · Glioblastoma (20) · Rectal Neoplasms (20) · Esophageal Neoplasms (19)
European Organisation for Research and Treatment of Cancer - EORTC (47) · Children's Oncology Group (33) · National Cancer Institute (NCI) (31) · Radiation Therapy Oncology Group (31) · Medical Research Council (17) · UNICANCER (16) · Alliance for Clinical Trials in Oncology (12) · Fudan University (12) · SWOG Cancer Research Network (12) · Sun Yat-sen University (12) · NRG Oncology (10) · Trans Tasman Radiation Oncology Group (8) · Eastern Cooperative Oncology Group (7) · Gynecologic Oncology Group (7) · International Atomic Energy Agency (7)
United States (213) · Canada (126) · United Kingdom (106) · France (98) · China (82) · Belgium (73) · Switzerland (70) · Australia (68) · Netherlands (67) · Germany (63) · Italy (61) · Spain (46) · New Zealand (38) · Puerto Rico (32) · Austria (29)
Edward G. Shaw, MD (4) · Al B. Benson, MD, FACP (3) · Dan Wang, Master (3) · Guoqiang Kong, Master (3) · Jean-Pierre Gerard, MD (3) · Jiachun Sun, Doctor (3) · Jing Ren, Master (3) · John R. Yarnold, MD, FRCR (3) · Michael G. Haddock, MD (3) · Michel Bolla, MD (3) · Roger Stupp, MD (3) · Ruina Yang, Master (3) · Ruinuo Jia, Master (3)
PMID 38603649, PMID 32691060, PMID 33242441, PMID 37505794, PMID 38320143, PMID 15172146, PMID 16467544, PMID 17236771, PMID 20138809, PMID 24121121, PMID 25023199, PMID 25592642, PMID 29926156, PMID 30523055, PMID 33539743, PMID 35731991, PMID 36346112, PMID 36596347, PMID 36603187, PMID 37890117, PMID 38421243, PMID 39121442, PMID 42085640, PMID 10549493, PMID 10663329, PMID 10869758, PMID 10924966, PMID 10974628, PMID 11181777, PMID 11448365, PMID 11586105, PMID 11917283, PMID 12007937, PMID 12111109, PMID 12117328, PMID 12126818, PMID 12153596, PMID 12160582, PMID 12204666, PMID 12239143, PMID 12377323, PMID 12499279, PMID 12694250, PMID 12697884, PMID 12743142, PMID 12756499, PMID 12780755, PMID 12838028, PMID 12927569, PMID 13129630
U10CA180886 (22), U10CA098543 (20), U10CA180868 (14), U10CA032102 (11), U10CA180820 (6), 2023 (5), U10CA021115 (5), U10CA031946 (5), U10CA180888 (5), 2005 (3), 2015 (3), 2019 (3), U10CA021661 (3), 2004 (2), 2008 (2)