701 completed. 701 Phase 2, 123 Phase 1, 21 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 701 | Completed 701 |
| Phase 1 | 123 | Completed 123 |
| Phase 3 | 21 | Completed 21 |
Follow Radiotherapy: new trials by email Literature Review of Radiotherapy trials Research Report on Radiotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial Comparing Low-Dose RT + Targeted Therapy+ Immunotherapy vs Targeted Therapy+ Immunotherapy Alone as Neoadjuvant Therapy in Operable HNSCC Patients. Tislelizumab, Afatinib, Low dose radiotherapy - Head and Neck Squamous Cell Carcinoma, Low-dose Radiotherapy | Phase 2 | Completed | West China Hospital | 98 | 2025-06-28 | 2026-06-30 |
| Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study Interleukin-2, Radiotherapy, Tislelizumab - Rectal Cancer | Phase 2 | Completed | The First Affiliated Hospital with Nanjing Medical University | 130 | 2024-08-18 | 2026-06-24 |
| Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors Lactobacillus reuteri Tablets, Placebo-containing tablets, Radiotherapy - Head and Neck Malignant Tumors | Phase 2 | Completed | West China Hospital | 160 | 2024-03-01 | 2025-12-19 |
| Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma Induction Immunotherapy-Toripalimab, Induction Chemotherapy-Albumin-paclitaxel combined with cisplatin, Radiotherapy - Esophageal Squamous Cell Carcinoma, Efficacy | Phase 2 | Completed | Sun Yat-sen University | 170 | 2024-02-15 | 2026-08-03 |
| Lactobacillus Rhamnosus GG Alleviates Oral Mucositis in Patients Undergoing Radiotherapy Lactobacillus rhamnosus GG, Placebo-containing tablets, Radiotherapy - Oral Mucositis | Phase 2 | Completed | West China Hospital | 160 | 2023-11-10 | 2026-09-09 |
| TN-TC11G (THC+CBD) Combination With Temozolomide and Radiotherapy in Patients With Newly-diagnosed Glioblastoma TN-TC11G, Temozolomide Oral Product, Radiotherapy - Glioblastoma | Phase 1 / Phase 2 | Completed | Grupo Español de Investigación en Neurooncología | 33 | 2023-08-18 | 2026-02-12 |
| Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors Terelizumab (aka Tislelizumab), CapeOx, Trastuzumab - Immunotherapy, Gastric Cancer | Phase 2 | Completed | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 189 | 2022-09-01 | 2026-04-01 |
| Study of Tislelizumab in Participants With Resectable Esophageal Squamous Cell Carcinoma Tislelizumab, Paclitaxel, Cisplatin - Resectable Esophageal Squamous Cell Carcinoma | Phase 2 | Completed | BeiGene | 70 | 2021-08-17 | 2025-12-01 |
| A Trial Evaluating Stereotactic Radiotherapy Plus Durvalumab Continuation for Patients With NSCLC Metachronous Oligometastatic Disease Under Durvalumab Consolidation Following Chemoradiation Radiotherapy + durvalumab - NSCLC | Phase 2 | Completed | Institut Claudius Regaud | 4 | 2021-05-27 | 2024-09-19 |
| A Study of Canakinumab With Chemotherapy, Radiation Therapy, and Durvalumab in People With Lung Cancer Canakinumab, Durvalumab, Radiation therapy - Non-small Cell Lung Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 41 | 2021-05-21 | 2026-07-08 |
| Phase II Study of Concurrent Lenvatinib and Radiotherapy for Advanced HCC concurrent lenvatinib and Radiotherapy, followed lenvatinib maintenance - Hepatocellular Carcinoma, Radiotherapy | Phase 2 | Completed | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 64 | 2021-04-12 | 2025-08-14 |
| Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin Cisplatin, Hearing Handicap Inventory for Adults - Screening, Radiation Therapy - Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Completed | Hyunseok Kang, MD | 16 | 2020-10-14 | 2024-06-28 |
| Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma Contrast-enhanced Magnetic Resonance Imaging, Ipilimumab, Nivolumab - Gliosarcoma, MGMT-Unmethylated Glioblastoma | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 159 | 2020-09-01 | 2026-04-22 |
| Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Resectable Esophageal Squamous Cell Carcinoma Durvalumab, Carboplatin, Paclitaxel - Esophageal Squamous Cell Carcinoma | Phase 2 | Completed | Peking Union Medical College Hospital | 60 | 2020-06-19 | 2024-01-22 |
| A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC) Radiation Therapy - Extensive-stage Small Cell Lung Cancer | Phase 2 | Completed | Second Xiangya Hospital of Central South University | 40 | 2020-06-01 | 2022-06-14 |
| Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors Leronlimab - Solid Tumor, Adult | Phase 2 | Completed | CytoDyn, Inc. | 16 | 2020-05-01 | 2026-01-23 |
| Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas Epacadostat, Bevacizumab, Radiation therapy - Glioma, Glioblastoma | Phase 2 | Completed | Washington University School of Medicine | 51 | 2020-04-20 | 2025-11-21 |
| Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer Radiotherapy, consolidation chemotherapy, TME or APR - Rectal Cancer | Phase 2 | Completed | Alexandria University | 58 | 2020-01-01 | 2022-03-11 |
| A Phase II Study of Chemoradiotherapy With Nimotuzumab in Unresectable Esophageal Cancer Radiotherapy, Nimotuzumab, S-1 - Esophageal Cancer, Chemoradiotherapy | Phase 2 | Completed | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 55 | 2019-11-14 | 2024-05-16 |
| Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer Nivolumab, Carboplatin, Paclitaxel - Oropharynx Squamous Cell Carcinoma | Phase 2 | Completed | University of Michigan Rogel Cancer Center | 26 | 2019-09-05 | 2026-01-22 |
Showing 20 of 701. Sign in to see all of them.
Lymphoma (69) · Carcinoma, Non-Small-Cell Lung (68) · Glioblastoma (66) · Head and Neck Neoplasms (66) · Lung Neoplasms (63) · Leukemia (54) · Central Nervous System Neoplasms (48) · Gliosarcoma (42) · Squamous Cell Carcinoma of Head and Neck (42) · Pancreatic Neoplasms (41) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (40) · Esophageal Neoplasms (39) · Rectal Neoplasms (37) · Breast Neoplasms (35) · Lymphoma, Follicular (35)
Radiation Therapy Oncology Group (44) · Alliance for Clinical Trials in Oncology (34) · National Cancer Institute (NCI) (31) · Memorial Sloan Kettering Cancer Center (28) · M.D. Anderson Cancer Center (23) · Fred Hutchinson Cancer Center (18) · Children's Oncology Group (17) · Case Comprehensive Cancer Center (15) · SWOG Cancer Research Network (13) · Eastern Cooperative Oncology Group (12) · European Organisation for Research and Treatment of Cancer - EORTC (9) · St. Jude Children's Research Hospital (9) · Northwestern University (8) · Roswell Park Cancer Institute (8) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (8)
United States (481) · Canada (65) · France (34) · China (30) · Netherlands (29) · United Kingdom (28) · Germany (27) · Switzerland (27) · Australia (25) · Spain (21) · Italy (20) · Belgium (17) · Puerto Rico (12) · New Zealand (9) · India (8)
Arthur William Blackstock, MD (4) · Annick Desjardins, MD, FRCPC (3) · Barbara Jean Bambach, MD (3) · Brenda W. Cooper, MD (3) · Burton L. Eisenberg, MD (3) · Christopher H. Crane, MD (3) · Corey J. Langer, MD (3) · Craig Moskowitz, MD (3) · David H. Ilson, MD, PhD (3) · David R. Spigel, MD (3) · Dirk De Ruysscher, MD, PhD (3) · Emanuele Zucca, MD (3) · Francisco Robert, MD, FACP (3)
PMID 25057165, PMID 40135712, PMID 25366678, PMID 27243238, PMID 32499241, PMID 32827353, PMID 34780125, PMID 35135810, PMID 10210538, PMID 10501910, PMID 11835236, PMID 11904735, PMID 12167786, PMID 12610186, PMID 12631594, PMID 12721251, PMID 1403051, PMID 14508361, PMID 14597741, PMID 14727242, PMID 14758134, PMID 14769135, PMID 14981168, PMID 15117425, PMID 15145163, PMID 15361643, PMID 15533252, PMID 15565574, PMID 15667949, PMID 15667956, PMID 15735120, PMID 15821648, PMID 15860857, PMID 15863167, PMID 16029787, PMID 16053699, PMID 16062075, PMID 16116597, PMID 16135463, PMID 16170174, PMID 16198508, PMID 16200343, PMID 16289906, PMID 16391300, PMID 16443947, PMID 16446336, PMID 16532436, PMID 16622435, PMID 16730138, PMID 16750317
P30CA043703 (14), U10CA032102 (14), U10CA031946 (13), U10CA021115 (9), U01CA062475 (7), U10CA098543 (7), P30CA016672 (6), P30CA006927 (5), P30CA006973 (5), P30CA008748 (5), P30CA022453 (5), U10CA021661 (5), U10CA180821 (5), 2009 (4), 2015 (3)