347 completed, 93 terminated, 55 active not recruiting, 46 recruiting. 639 Phase 1, 245 Phase 2.
Follow Radiotherapy: new trials by email Literature Review of Radiotherapy trials Research Report on Radiotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NG101m Adjuvant Therapy in Glioblastoma Patients Intensity-modulated radiation therapy, Temozolomide, NG101m - Glioblastoma Multiforme | Phase 1 / Phase 2 | Not yet recruiting | NeuGATE Theranostics | 52 | 2027-01-01 | 2025-10-21 |
| Testing Safe Doses of Anti-Cancer Medicines, 5-Flurouracil (5-FU) and Tretinoin (ATRA), Added to the Usual Cancer Treatment of Ependymoma Biospecimen Collection, Echocardiography Test, Fluorouracil - Childhood Posterior Fossa Ependymoma | Phase 1 / Phase 2 | Not yet recruiting | Children's Oncology Group | 70 | 2026-12-11 | 2026-09-30 |
| Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer Neoadjuvant Chemotherapy, Radiation Therapy, MRI - Breast Cancer, HER2-positive Breast Cancer | Phase 1 / Phase 2 | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 84 | 2026-09-15 | 2026-06-24 |
| Thermotherapy for Head and Neck Cancer Patients Thermotherapy, Radiotherapy, Concurrent chemoradiation - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Recruiting | Erasmus Medical Center | 30 | 2026-09-01 | 2026-09-02 |
| A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab Computed Tomography, Copper Cu 64-DOTA-pembrolizumab, Low Dose Radiation Therapy - Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain | Phase 1 | Recruiting | City of Hope Medical Center | 6 | 2026-09-01 | 2026-10-19 |
| Radiation to Treat Joint Damage Caused by Cancer Immunotherapy Low dose radiation therapy - Arthritis, Arthropathy | Phase 1 | Not yet recruiting | University of Chicago | 20 | 2026-08-26 | 2026-03-23 |
| Low-Dose Radiotherapy for Alzheimer's Disease Low Dose Radiation Therapy - Alzheimer Dementia, Dementia | Phase 1 / Phase 2 | Recruiting | Evan Thomas | 50 | 2026-07-15 | 2026-07-09 |
| Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac MR-Linac System, Radiation Therapy, Temozolomide - High-grade Glioma | Phase 1 | Not yet recruiting | NYU Langone Health | 20 | 2026-06-01 | 2026-03-09 |
| Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas Vancomycin 125mg, Radiation Therapy, CAR-T - Large B Cell Lymphoma, Non Hodgkin Lymphoma (NHL) | Phase 1 | Recruiting | Abramson Cancer Center at Penn Medicine | 14 | 2026-05-29 | 2026-07-01 |
| Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue Sarcoma Biopsy, Biospecimen Collection, Computed Tomography - Soft Tissue Sarcoma | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2026-05-15 | 2025-08-26 | |
| A Study of Ta-NPs Plus Radiotherapy for Locally Recurrent Retroperitoneal Sarcoma Ta-NPs (2% Tumor Volume), Ta-NPs (5% Tumor Volume), Ta-NPs (10% Tumor Volume) - Locally Recurrent Retroperitoneal Soft Tissue Sarcoma | Phase 1 | Not yet recruiting | West China Hospital | 9 | 2026-05-01 | 2026-05-11 |
| Re-radiotherapy Combined With Chidamide for the Treatment of Recurrent Head and Neck Squamous Cell Carcinoma After Radiotherapy Chidamide, radiotherapy - Head and Neck Squamous Cell Carcinoma HNSCC | Phase 1 | Recruiting | West China Hospital | 6 | 2026-04-23 | 2026-04-28 |
| Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas Fludarabine, Cyclophosphamide, B7-H3-CAR T Cells - Sarcoma, Childhood Osteosarcoma | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 42 | 2026-01-21 | 2026-02-09 |
| Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers Capecitabine, Docetaxel, Fluorouracil - Clinical Stage I Gastric Cancer AJCC v8, Clinical Stage II Gastric Cancer AJCC v8 | Phase 1 | Withdrawn | Ohio State University Comprehensive Cancer Center | 2025-12-31 | 2025-02-07 | |
| A Phase I Study of WTX212A Monotherapy or in Combination With Radiotherapy in Patients With Advanced Solid Tumors WTX212A injection, radiotherapy - Solid Tumor Cancer, Cancer | Phase 1 | Recruiting | Sun Yat-sen University | 12 | 2025-11-25 | 2025-12-08 |
| A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases SHR-A1811, radiotherapy - Breast Cancer, Brain Metastases | Phase 1 / Phase 2 | Not yet recruiting | Peking University Cancer Hospital & Institute | 51 | 2025-09-30 | 2025-09-17 |
| LDRT Combined With Pucotenlimab and Standard Therapy for Advanced Pancreatic Cancer: A Single-Arm Study Low-dose Radiotherapy, Pucotenlimab, AG regimen - Pancreatic Cancer, PD-L1 | Phase 1 / Phase 2 | Recruiting | Zhejiang Provincial People's Hospital | 10 | 2025-09-30 | 2026-01-26 |
| TAS-102 Plus Radiotherapy in Elderly ESCC TAS-102, Radiotherapy - ESCC, TAS 102 | Phase 1 / Phase 2 | Not yet recruiting | Qianfoshan Hospital | 45 | 2025-09-25 | 2025-09-29 |
| Low Dose Radiotherapy for Heart Failure Radiation Therapy - Heart Failure - NYHA II - IV | Phase 1 / Phase 2 | Not yet recruiting | Hospital do Coracao | 10 | 2025-07-14 | 2025-06-25 |
| An Exploratory Clinical Study of Nimotuzumab in Bladder - Sparing Chemoradiotherapy for Muscle - Invasive Bladder Cancer Nimotuzumab and Radiotherapy - Bladder (Urothelial, Transitional Cell) Cancer | Phase 1 | Not yet recruiting | Peking University First Hospital | 30 | 2025-06-30 | 2025-07-08 |
Showing 20 of 639. Sign in to see all of them.
Glioblastoma (90) · Carcinoma, Non-Small-Cell Lung (78) · Lung Neoplasms (62) · Head and Neck Neoplasms (49) · Squamous Cell Carcinoma of Head and Neck (42) · Gliosarcoma (41) · Central Nervous System Neoplasms (37) · Pancreatic Neoplasms (33) · Brain Neoplasms (31) · Rectal Neoplasms (31) · Sarcoma (28) · Breast Neoplasms (26) · Esophageal Neoplasms (26) · Glioma (25) · Lymphoma (24)
M.D. Anderson Cancer Center (53) · National Cancer Institute (NCI) (47) · Memorial Sloan Kettering Cancer Center (15) · Radiation Therapy Oncology Group (15) · Abramson Cancer Center at Penn Medicine (11) · Fred Hutchinson Cancer Center (11) · H. Lee Moffitt Cancer Center and Research Institute (11) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (11) · Dana-Farber Cancer Institute (10) · Northwestern University (10) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (9) · Alliance for Clinical Trials in Oncology (8) · Massachusetts General Hospital (8) · Sichuan University (8) · Children's Oncology Group (7)
United States (465) · China (38) · Canada (28) · France (21) · United Kingdom (19) · Germany (17) · Netherlands (17) · Switzerland (16) · Spain (15) · Australia (13) · Belgium (6) · Italy (6) · Norway (6) · Sweden (5) · Finland (4)
You Lu, MD (5) · Peter W. Pisters, MD (4) · Amol J. Ghia, MD (3) · Arthur William Blackstock, MD (3) · Corey J. Langer, MD (3) · Deborah E Citrin, M.D. (3) · Francisco Robert, MD, FACP (3) · James L. Pearlman, MD (3) · Anders Johnsson, MD, PhD (2) · Anne S Tsao (2) · Aude Chapuis (2) · Bert H. O'Neil, MD (2) · Brian Czito, MD (2)
PMID 34780125, PMID 32827353, PMID 31500595, PMID 39863139, PMID 10501910, PMID 10797354, PMID 12171484, PMID 12631594, PMID 12885811, PMID 15117425, PMID 15246197, PMID 15328179, PMID 15667949, PMID 15863167, PMID 15890573, PMID 16116597, PMID 16170174, PMID 16198508, PMID 16391300, PMID 16421427, PMID 16520474, PMID 16730134, PMID 16855840, PMID 16889823, PMID 17084549, PMID 17278121, PMID 17308042, PMID 17336213, PMID 17410043, PMID 17482376, PMID 17560737, PMID 17869017, PMID 17896890, PMID 18299147, PMID 18394819, PMID 18418404, PMID 18565686, PMID 18723297, PMID 18845990, PMID 19010522, PMID 19060587, PMID 19096311, PMID 19100600, PMID 19179301, PMID 19509178, PMID 19525947, PMID 19533025, PMID 19536893, PMID 19540060, PMID 19596976
P30CA016672 (9), P30CA006973 (7), P30CA033572 (7), 2018 (5), U01CA062475 (5), U10CA180868 (5), P30CA006927 (4), P30CA043703 (4), P30CA060553 (4), P30CA068485 (4), 2016 (3), 2017 (3), 2023 (3), P30CA006516 (3), P30CA015704 (3)